Search Results - "BRUELL, Christian"

Genetic analysis of interactions with eukaryotic rRNA identify the mitoribosome as target in aminoglycoside ototoxicity by Hobbie, Sven N, Akshay, Subramanian, Kalapala, Sarath K, Bruell, Christian M, Shcherbakov, Dmitry, Böttger, Erik C

“…Aminoglycoside ototoxicity has been related to a surprisingly large number of cellular structures and metabolic pathways. The finding that patients with…”
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Mitochondrial deafness alleles confer misreading of the genetic code by Hobbie, Sven N, Bruell, Christian M, Akshay, Subramanian, Kalapala, Sarath K, Shcherbakov, Dmitry, Böttger, Erik C

“…Despite the fact that important genetic diseases are caused by mutant mitochondrial ribosomes, the molecular mechanisms by which such ribosomes result in a…”
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Essential Mechanisms in the Catalysis of Peptide Bond Formation on the Ribosome by Beringer, Malte, Bruell, Christian, Xiong, Liqun, Pfister, Peter, Bieling, Peter, Katunin, Vladimir I., Mankin, Alexander S., Böttger, Erik C., Rodnina, Marina V.

“…Peptide bond formation is the main catalytic function of the ribo-some. The mechanism of catalysis is presumed to be highly conserved in all organisms. We…”
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23S rRNA Base Pair 2057-2611 Determines Ketolide Susceptibility and Fitness Cost of the Macrolide Resistance Mutation 2058A→G by Pfister, Peter, Corti, Natascia, Hobbie, Sven, Bruell, Christian, Zarivach, Raz, Yonath, Ada, Böttger, Erik C.

“…The 23S rRNA A2058G alteration mediates macrolide, lincosamide, and streptogramin B resistance in the bacterial domain and determines the selectivity of…”
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Binding of Neomycin-Class Aminoglycoside Antibiotics to Mutant Ribosomes with Alterations in the A Site of 16S rRNA by HOBBIE, Sven N, PFISTER, Peter, BRUELL, Christian, SANDER, Peter, FRANCOIS, Boris, WESTHOF, Eric, BÖTTGER, Erik C

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Conservation of Bacterial Protein Synthesis Machinery: Initiation and Elongation in Mycobacterium smegmatis by Bruell, Christian M, Eichholz, Carolin, Kubarenko, Andriy, Post, Virginia, Katunin, Vladimir I, Hobbie, Sven N, Rodnina, Marina V, Böttger, Erik C

“…Most of our understanding of ribosome function is based on experiments utilizing translational components from Escherichia coli. It is not clear to which…”
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Engineering the rRNA decoding site of eukaryotic cytosolic ribosomes in bacteria by Hobbie, Sven N, Kalapala, Sarath K, Akshay, Subramanian, Bruell, Christian, Schmidt, Sebastian, Dabow, Sabine, Vasella, Andrea, Sander, Peter, Böttger, Erik C

“…Structural and genetic studies on prokaryotic ribosomes have provided important insights into fundamental aspects of protein synthesis and translational…”
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Analysis of the Contribution of Individual Substituents in 4,6-Aminoglycoside-Ribosome Interaction by HOBBLE, Sven N, PFISTER, Peter, BRÜLL, Christian, WESTHOF, Eric, BÖTTGER, Erik C

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A gives G by Pfister, Peter, Corti, Natascia, Hobbie, Sven, Bruell, Christian

“…The 23S rRNA A2058G alteration mediates macrolide, lincosamide, and streptogramin B resistance in the bacterial domain and determines the selectivity of…”
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23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A arrow right G by Pfister, Peter, Corti, Natascia, Hobbie, Sven, Bruell, Christian, Zarivach, Raz, Yonath, Ada, Boettger, Erik C

“…The 23S rRNA A2058G alteration mediates macrolide, lincosamide, and streptogramin B resistance in the bacterial domain and determines the selectivity of…”
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