Search Results - "BRUCE, N"

Prolonging healthy aging: Longevity vitamins and proteins by Ames, Bruce N.

“…It is proposed that proteins/enzymes be classified into two classes according to their essentiality for immediate survival/reproduction and their function in…”
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The RDoC framework: facilitating transition from ICD/DSM to dimensional approaches that integrate neuroscience and psychopathology by Cuthbert, Bruce N.

“…In 2008, the National Institute of Mental Health (NIMH) included in its new Strategic Plan the following aim: “Develop, for research purposes, new ways of…”
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Methotrexate and its mechanisms of action in inflammatory arthritis by Cronstein, Bruce N., Aune, Thomas M.

“…Despite the introduction of numerous biologic agents for the treatment of rheumatoid arthritis (RA) and other forms of inflammatory arthritis, low-dose…”
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Research Domain Criteria (RDoC): Progress and Potential by Cuthbert, Bruce N.

“…The National Institute of Mental Health (NIMH) addressed in its 2008 Strategic Plan an emerging concern that the current diagnostic system was hampering…”
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Key challenges to expanding renewable energy by Stram, Bruce N.

“…The key advantage of renewables is that they are free of direct pollution and carbon emissions. Given concern over global warming caused by carbon emissions,…”
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The NIMH Research Domain Criteria Initiative: Background, Issues, and Pragmatics by Kozak, Michael J., Cuthbert, Bruce N.

“…This article describes the National Institute of Mental Health's Research Domain Criteria (RDoC) initiative. The description includes background, rationale,…”
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Brain disorders? Precisely by Insel, Thomas R, Cuthbert, Bruce N

“…Precision medicine comes to psychiatry Mental disorders represent a public health challenge of staggering proportions. In the most recent Global Burden of…”
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Research Domain Criteria: toward future psychiatric nosologies by Cuthbert, Bruce N.

“…The Research Domain Criteria (RDoC) project was initiated by the National Institute of Mental Health (NIMH) in early 2009 as the implementation of Goal 1.4 of…”
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Adenosine and adenosine receptors in the pathogenesis and treatment of rheumatic diseases by Cronstein, Bruce N., Sitkovsky, Michail

“…Key Points Adenosine, generated from the extracellular hydrolysis of ATP, is a potent endogenous regulator of inflammation and immune reactions via interaction…”
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Vitamin D and the omega‐3 fatty acids control serotonin synthesis and action, part 2: relevance for ADHD, bipolar disorder, schizophrenia, and impulsive behavior by Patrick, Rhonda P., Ames, Bruce N.

“…ABSTRACT Serotonin regulates a wide variety of brain functions and behaviors. Here, we synthesize previous findings that serotonin regulates executive…”
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The role of RDoC in future classification of mental disorders by Cuthbert, Bruce N.

“…The Research Domain Criteria (RDoC) project constitutes a translational framework for psychopathology research, initiated by the National Institute of Mental…”
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Vitamin D hormone regulates serotonin synthesis. Part 1: relevance for autism by Patrick, Rhonda P., Ames, Bruce N.

“…ABSTRACT Serotonin and vitamin D have been proposed to play a role in autism; however, no causal mechanism has been established. Here, we present evidence that…”
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Toward the future of psychiatric diagnosis: the seven pillars of RDoC by Cuthbert, Bruce N, Insel, Thomas R

“…Current diagnostic systems for mental disorders rely upon presenting signs and symptoms, with the result that current definitions do not adequately reflect…”
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Translating intermediate phenotypes to psychopathology: The NIMH Research Domain Criteria by Cuthbert, Bruce N.

“…The Research Domain Criteria project (RDoC) was initiated by the National Institute of Mental Health in early 2009 to “develop, for research purposes, new ways…”
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Trial of Anifrolumab in Active Systemic Lupus Erythematosus by Morand, Eric F, Furie, Richard, Tanaka, Yoshiya, Bruce, Ian N, Askanase, Anca D, Richez, Christophe, Bae, Sang-Cheol, Brohawn, Philip Z, Pineda, Lilia, Berglind, Anna, Tummala, Raj

“…A phase 3 trial of anifrolumab, a monoclonal antibody to type I interferon receptor subunit 1, showed benefit in a composite primary end point of lupus scores…”
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Low Micronutrient Intake May Accelerate the Degenerative Diseases of Aging through Allocation of Scarce Micronutrients by Triage by Ames, Bruce N.

“…Inadequate dietary intakes of vitamins and minerals are widespread, most likely due to excessive consumption of energy-rich, micronutrient-poor, refined food…”
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Musings in the twilight of my career by Ames, Bruce N.

“…I present a summary of my research during the last few decades of research which focused on understanding the biochemical basis for maintaining an optimum…”
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Does the High Prevalence of Vitamin D Deficiency in African Americans Contribute to Health Disparities? by Ames, Bruce N, Grant, William B, Willett, Walter C

“…African Americans have higher incidence of, and mortality from, many health-related problems than European Americans. They also have a 15 to 20-fold higher…”
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International Union of Basic and Clinical Pharmacology. CXII: Adenosine Receptors: A Further Update by IJzerman, Adriaan P, Jacobson, Kenneth A, Müller, Christa E, Cronstein, Bruce N, Cunha, Rodrigo A

“…Our previous International Union of Basic and Clinical Pharmacology report on the nomenclature and classification of adenosine receptors (2011) contained a…”
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The ecology of human–carnivore coexistence by Lamb, Clayton T., Ford, Adam T., McLellan, Bruce N., Proctor, Michael F., Mowat, Garth, Ciarniello, Lana, Nielsen, Scott E., Boutin, Stan

“…With a shrinking supply of wilderness and growing recognition that top predators can have a profound influence on ecosystems, the persistence of large…”
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