Search Results - "BROWN, Russell"

Fetuin B Is a Secreted Hepatocyte Factor Linking Steatosis to Impaired Glucose Metabolism by Meex, Ruth C., Hoy, Andrew J., Morris, Alexander, Brown, Russell D., Lo, Jennifer C.Y., Burke, Melissa, Goode, Robert J.A., Kingwell, Bronwyn A., Kraakman, Michael J., Febbraio, Mark A., Greve, Jan Willem, Rensen, Sander S., Molloy, Mark P., Lancaster, Graeme I., Bruce, Clinton R., Watt, Matthew J.

“…Liver steatosis is associated with the development of insulin resistance and the pathogenesis of type 2 diabetes. We tested the hypothesis that protein signals…”
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Leptin Mediates the Increase in Blood Pressure Associated with Obesity by Simonds, Stephanie E., Pryor, Jack T., Ravussin, Eric, Greenway, Frank L., Dileone, Ralph, Allen, Andrew M., Bassi, Jaspreet, Elmquist, Joel K., Keogh, Julia M., Henning, Elana, Myers, Martin G., Licinio, Julio, Brown, Russell D., Enriori, Pablo J., O’Rahilly, Stephen, Sternson, Scott M., Grove, Kevin L., Spanswick, David C., Farooqi, I. Sadaf, Cowley, Michael A.

“…Obesity is associated with increased blood pressure (BP), which in turn increases the risk of cardiovascular diseases. We found that the increase in leptin…”
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Using sexual orientation and gender identity data in electronic health records to assess for disparities in preventive health screening services by Grasso, Chris, Goldhammer, Hilary, Brown, Russell J., Furness, B.W.

“…•Sexual orientation and gender identity data are critical for healthcare•Organizations can stratify this data to detect disparities for LGBTQ people•This is th…”
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Ceramides Contained in LDL Are Elevated in Type 2 Diabetes and Promote Inflammation and Skeletal Muscle Insulin Resistance by BOON, James, HOY, Andrew J, BRUCE, Clinton R, WATT, Matthew J, STARK, Romana, BROWN, Russell D, MEEX, Ruth C, HENSTRIDGE, Darren C, SCHENK, Simon, MEIKLE, Peter J, HOROWITZ, Jeffrey F, KINGWELL, Bronwyn A

“…Dysregulated lipid metabolism and inflammation are linked to the development of insulin resistance in obesity, and the intracellular accumulation of the…”
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An adenine/thymidine-rich region is integral to RepL-mediated DNA replication by Huan, Yang Wei, Brown, Russell, Wang, Baojun

“…The lytic replication of bacteriophage P1 requires RepL expression and the lytic stage origin, oriL, which is postulated to be located within gene sequence…”
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The “His and Hers” of the Renin-Angiotensin System by Hilliard, Lucinda M., Sampson, Amanda K., Brown, Russell D., Denton, Kate M.

“…Sex differences exist in the regulation of arterial pressure and renal function by the renin-angiotensin system (RAS). This may in part stem from a…”
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Bidirectional control of infant rat social behavior via dopaminergic innervation of the basolateral amygdala by Opendak, Maya, Raineki, Charlis, Perry, Rosemarie E., Rincón-Cortés, Millie, Song, Soomin C., Zanca, Roseanna M., Wood, Emma, Packard, Katherine, Hu, Shannon, Woo, Joyce, Martinez, Krissian, Vinod, K. Yaragudri, Brown, Russell W., Deehan, Gerald A., Froemke, Robert C., Serrano, Peter A., Wilson, Donald A., Sullivan, Regina M.

“…Social interaction deficits seen in psychiatric disorders emerge in early-life and are most closely linked to aberrant neural circuit function. Due to…”
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Reinstatement of nicotine conditioned place preference in a transgenerational model of drug abuse vulnerability in psychosis: Impact of BDNF on the saliency of drug associations by Peeters, Loren D., Wills, Liza J., Cuozzo, Anthony M., Ivanich, Kira L., Brown, Russell W.

“…Rationale Psychotic disorders such as schizophrenia are often accompanied by high rates of cigarette smoking, reduced quit success, and high relapse rates,…”
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The adenosine A(2A) receptor agonist CGS 21680 alleviates auditory sensorimotor gating deficits and increases in accumbal CREB in rats neonatally treated with quinpirole by Brown, Russell W., Bhide, Pradeep G., Gill, W. Drew, Peeters, Loren D.

“…Rationale and objective The adenosine A(2A) receptor forms a mutually inhibitory heteromer with the dopamine D 2 receptor, and A(2A) agonists decrease D 2…”
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Transgenerational evidence of increases in dopamine D2 receptor sensitivity in rodents: Impact on sensorimotor gating, the behavioral response to nicotine and BDNF by Gill, Wesley Drew, Burgess, Katherine C, Vied, Cynthia, Brown, Russell W

“…Background/Aims: Neonatal quinpirole (NQ) treatment to rats increases dopamine D2 (DAD2) receptor sensitivity in adult animals. We investigated if increased…”
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The effects of a novel inhibitor of tumor necrosis factor (TNF) alpha on prepulse inhibition and microglial activation in two distinct rodent models of schizophrenia by Shelton, Heath W., Gabbita, S. Prasad, Gill, W. Drew, Burgess, Katherine C., Whicker, Wyatt S., Brown, Russell W.

“…•Two rodent models of schizophrenia were tested on behavior and neuroinflammation.•One model focused on the dopamine system, the other on immune system…”
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Modulation of mGlu5 reduces rewarding associative properties of nicotine via changes in mesolimbic plasticity: Relevance to comorbid cigarette smoking in psychosis by Peeters, Loren D., Wills, Liza J., Cuozzo, Anthony M., Ivanich, Kira L., Turney, Seth E., Bullock, Luke P., Price, Robert M., Gass, Justin T., Brown, Russell W.

“…Antipsychotic medications that are used to treat psychosis are often limited in their efficacy by high rates of severe side effects. Treatment success in…”
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Modulation of mGlu5 improves sensorimotor gating deficits in rats neonatally treated with quinpirole through changes in dopamine D2 signaling by Brown, Russell W., Varnum, Christopher G., Wills, Liza J., Peeters, Loren D., Gass, Justin T.

“…This study analyzed whether the positive allosteric modulator of metabotropic glutamate receptor type 5 (mGlu5) 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)…”
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Ciliary neurotrophic factor is a key sex-specific regulator of depressive-like behavior in mice by Jia, Cuihong, Brown, Russell W., Malone, Hannah M., Burgess, Katherine C., Gill, W. Drew, Keasey, Matthew P., Hagg, Theo

“…•CNTF plays a sex-specific role in depressive-like behavior.•CNTF is pro-depressive in female mice but anti-depressive in male mice.•The anti-depressant effect…”
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Sex Differences in the Pressor and Tubuloglomerular Feedback Response to Angiotensin II by Brown, Russell D, Hilliard, Lucinda M, Head, Geoffrey A, Jones, Emma S, Widdop, Robert E, Denton, Kate M

“…Awareness of sex differences in the pathology of cardiovascular disease is increasing. Previously, we have shown a role for the angiotensin type 2 receptor…”
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Effects of positive mGlu5 modulation on D2 signaling and nicotine-conditioned place preference: Mechanisms of epigenetic inheritance in a transgenerational model of drug abuse vulnerability in psychosis by Peeters, Loren D, Wills, Liza J, Cuozzo, Anthony M, Ahmed, Cristal D, Massey, Samuel R, Chen, Wanqiu, Chen, Zhong, Wang, Charles, Gass, Justin T, Brown, Russell W

“…The metabotropic glutamate type 5 (mGlu5) receptor has emerged as a potential target for the treatment of psychosis that is suggested to have greater efficacy…”
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Hypothalamic kiss1 mRNA and kisspeptin immunoreactivity are reduced in a rat model of polycystic ovary syndrome (PCOS) by Brown, Russell E, Wilkinson, Diane A, Imran, Syed A, Caraty, Alain, Wilkinson, Michael

“…Abstract An intact hypothalamic kiss1 /kisspeptin/kiss1r complex is a prerequisite for reproductive competence, and kisspeptin treatment could be a practical…”
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Sex- and age-related differences in the chronic pressure-natriuresis relationship: role of the angiotensin type 2 receptor by Mirabito, Katrina M, Hilliard, Lucinda M, Kett, Michelle M, Brown, Russell D, Booth, Sean C, Widdop, Robert E, Moritz, Karen M, Evans, Roger G, Denton, Kate M

“…Sex hormones regulate the renin-angiotensin system. For example, estrogen enhances expression of the angiotensin type 2 receptor. We hypothesized that…”
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Effects of an adenosine A2A agonist on the rewarding associative properties of nicotine and neural plasticity in a rodent model of schizophrenia by Gill, Wesley Drew, Shelton, Heath W, Burgess, Katherine C, Brown, Russell W

“…Background: Adenosine A2a receptors form a mutually inhibitory heteromeric complex with dopamine D2 receptors such that each receptor exhibits lower…”
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Astrocyte focal adhesion kinase reduces passive stress coping by inhibiting ciliary neurotrophic factor only in female mice by Jia, Cuihong, Gill, W. Drew, Lovins, Chiharu, Brown, Russell W., Hagg, Theo

“…Astrocytes have been implicated in stress responses and produce ciliary neurotrophic factor (CNTF), which we have shown in the mouse medial amygdala (MeA) to…”
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