Search Results - "BROWN, H. R"

Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice by Clement, A. M., Nguyen, M. D., Roberts, E. A., Garcia, M. L., Boillée, S., Rule, M., McMahon, A. P., Doucette, W., Siwek, D., Ferrante, R. J., Brown, R. H., J. -P. Julien, Goldstein, L. S. B., Cleveland, D. W.

“…The most common form of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease affecting adult motor neurons, is caused by dominant mutations in the…”
Get full text

A locus on chromosome 9p confers susceptibility to ALS and frontotemporal dementia by MORITA, M, AL-CHALABI, A, JONGJAROENPRASERT, W, HORVITZ, H. R, GUNNARSSON, L.-G, BROWN, R. H, ANDERSEN, P. M, HOSLER, B, SAPP, P, ENGLUND, E, MITCHELL, J. E, HABGOOD, J. J, DE BELLEROCHE, J, XI, J

“…To perform genetic linkage analysis in a family affected with ALS and frontotemporal dementia (FTD). The authors performed a genome-wide linkage analysis of a…”
Get full text

Analysis of FUS gene mutation in familial amyotrophic lateral sclerosis within an Italian cohort by TICOZZI, N, SILANI, V, BROWN, R. H, LANDERS, J. E, LECLERC, A. L, KEAGLE, P, GELLERA, C, RATTI, A, TARONI, F, KWIATKOWSKI, T. J, MCKENNA-YASEK, D. M, SAPP, P. C

“…Mutations in the FUS gene on chromosome 16 have been recently discovered as a cause of familial amyotrophic lateral sclerosis (FALS). This study determined the…”
Get full text

The identification of liquid ethane in Titan's Ontario Lacus by Brown, R. H, Soderblom, L. A, Soderblom, J. M, Clark, R. N, Jaumann, R, Barnes, J. W, Sotin, C, Buratti, B, Baines, K. H, Nicholson, P. D

“…Titan was once thought to have global oceans of light hydrocarbons on its surface, but after 40 close flybys of Titan by the Cassini spacecraft, it has become…”
Get full text

Quantification of reverse transcriptase in ALS and elimination of a novel retroviral candidate by MCCORMICK, A. L, BROWN, R. H, CUDKOWICZ, M. E, AL-CHALABI, A, GARSON, J. A

“…Retroviral involvement in amyotrophic lateral sclerosis (ALS) has been suspected for several years since the recognition that both murine and human…”
Get full text

Mutational analysis reveals the FUS homolog TAF15 as a candidate gene for familial amyotrophic lateral sclerosis by Ticozzi, N., Vance, C., LeClerc, A.L., Keagle, P., Glass, J.D., McKenna-Yasek, D., Sapp, P.C., Silani, V., Bosco, D.A., Shaw, C.E., Brown Jr, R.H., Landers, J.E.

“…FUS, EWS, and TAF15 belong to the TET family of structurally similar DNA/RNA‐binding proteins. Mutations in the FUS gene have recently been discovered as a…”
Get full text

Identification of potential CSF biomarkers in ALS by PASINETTI, G. M, UNGAR, L. H, MARCUS, S, HO, L, LANGEE, D. J, YEMUL, S, DENG, H, YUAN, X, BROWN, R. H, CUDKOWICZ, M. E, NEWHALL, K, PESKIND, E

“…The clinical diagnosis of ALS is based entirely on clinical features. Identification of biomarkers for ALS would be important for diagnosis and might also…”
Get full text

Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis by Kwiatkowski, T.J. Jr, Bosco, D.A, LeClerc, A.L, Tamrazian, E, Vanderburg, C.R, Russ, C, Davis, A, Gilchrist, J, Kasarskis, E.J, Munsat, T, Valdmanis, P, Rouleau, G.A, Hosler, B.A, Cortelli, P, de Jong, P.J, Yoshinaga, Y, Haines, J.L, Pericak-Vance, M.A, Yan, J, Ticozzi, N, Siddique, T, McKenna-Yasek, D, Sapp, P.C, Horvitz, H.R, Landers, J.E, Brown, R.H. Jr

“…Amyotrophic lateral sclerosis (ALS) is a fatal degenerative motor neuron disorder. Ten percent of cases are inherited; most involve unidentified genes. We…”
Get full text

Cloud features and zonal wind measurements of Saturn's atmosphere as observed by Cassini/VIMS by Choi, D. S., Showman, A. P., Brown, R. H.

“…We present an analysis of data about Saturn's atmosphere from Cassini's Visual and Infrared Mapping Spectrometer (VIMS), focusing on the meteorology of the…”
Get full text

Spectral Observations of the Enceladus Plume with Cassini-Vims by Hedman, M. M, Nicholson, P. D, Showalter, M. R, Brown, R. H, Buratti, B. J, Clark, R. N

“…On 2005 November 27 (day 331), the Visual and Infrared Mapping Spectrometer instrument onboard the Cassini spacecraft obtained high signal-to-noise, spatially…”
Get full text

Hapke modeling of Rhea surface properties through Cassini-VIMS spectra by Ciarniello, M., Capaccioni, F., Filacchione, G., Clark, R.N., Cruikshank, D.P., Cerroni, P., Coradini, A., Brown, R.H., Buratti, B.J., Tosi, F., Stephan, K.

“…► Rhea’s spectrum and phase function modeling. ► Spectra from VIMS on board Cassini spacecraft. ► Intraparticle mixture of water ice and Triton tholin…”
Get full text

Inflammation in dysferlin myopathy: Immunohistochemical characterization of 13 patients by GALLARDO, E, ROJAS-GARCIA, R, DE LUNA, N, POU, A, BROWN, R. H, ILLA, I

“…Inflammation was detected in 9 of 13 patients with different phenotypes of dysferlin myopathy. Endomysial or perivascular infiltrates consisted of 11.1% +/-…”
Get full text

Observations of Titan’s Northern lakes at 5μm: Implications for the organic cycle and geology by Sotin, C., Lawrence, K.J., Reinhardt, B., Barnes, J.W., Brown, R.H., Hayes, A.G., Le Mouélic, S., Rodriguez, S., Soderblom, J.M., Soderblom, L.A., Baines, K.H., Buratti, B.J., Clark, R.N., Jaumann, R., Nicholson, P.D., Stephan, K.

“…► First infrared observation of Ligeia Mare and several small lakes in Titan’s Northern polar area. ► This paper demonstrates that the lakes have not evolved…”
Get full text

Dynamic auroral storms on Saturn as observed by the Hubble Space Telescope by Nichols, J. D., V.Badman, S., Baines, K. H., Brown, R. H., Bunce, E. J., Clarke, J. T., Cowley, S. W. H., Crary, F. J., Dougherty, M. K., Gérard, J.-C., Grocott, A., Grodent, D., Kurth, W. S., Melin, H., Mitchell, D. G., Pryor, W. R., Stallard, T. S.

“…We present observations of significant dynamics within two UV auroral storms observed on Saturn using the Hubble Space Telescope in April/May 2013…”
Get full text

Effect of bronchial thermoplasty on airway distensibility by Brown, R. H, Wizeman, W, Danek, C, Mitzner, W

“…Recent studies have reported that the application of thermal energy delivered through a bronchoscope (bronchial thermoplasty) impairs the ability of airways to…”
Get full text

Titan’s cloud seasonal activity from winter to spring with Cassini/VIMS by Rodriguez, S., Le Mouélic, S., Rannou, P., Sotin, C., Brown, R.H., Barnes, J.W., Griffith, C.A., Burgalat, J., Baines, K.H., Buratti, B.J., Clark, R.N., Nicholson, P.D.

“…► An extensive and stable cloud caps the winter pole. ► Transient, convective clouds form in the summer hemisphere at preferential latitudes. ► At summer pole…”
Get full text

Cassini observations of ion and electron beams at Saturn and their relationship to infrared auroral arcs by Badman, S. V., Achilleos, N., Arridge, C. S., Baines, K. H., Brown, R. H., Bunce, E. J., Coates, A. J., Cowley, S. W. H., Dougherty, M. K., Fujimoto, M., Hospodarsky, G., Kasahara, S., Kimura, T., Melin, H., Mitchell, D. G., Stallard, T., Tao, C.

“…We present Cassini Visual and Infrared Mapping Spectrometer observations of infrared auroral emissions from the noon sector of Saturn's ionosphere revealing…”
Get full text

The use of Singapore flaps for vaginal reconstruction in women with vaginal stenosis with obstetric fistula: a surgical technique by Pope, RJ, Brown, RH, Chipungu, E, Hollier, LH, Wilkinson, JP

“…Gynecologic and plastic surgeons collaborate to improve vaginal reconstruction for women with vaginal stenosis and obstetric fistula. As these cases occur…”
Get full text

Detection of serum reverse transcriptase activity in patients with ALS and unaffected blood relatives by STEELE, A. J, AL-CHALABI, A, FERRANTE, K, CUDKOWICZ, M. E, BROWN, R. H, GARSON, J. A

“…Retroviral involvement in the etiology of sporadic ALS has been suspected for several years since the recognition that both murine and human retroviruses can…”
Get full text

Rats Expressing Human Cytosolic Copper-Zinc Superoxide Dismutase Transgenes with Amyotrophic Lateral Sclerosis: Associated Mutations Develop Motor Neuron Disease by Nagai, Makiko, Aoki, Masashi, Miyoshi, Ichiro, Kato, Masaaki, Pasinelli, Piera, Kasai, Noriyuki, Brown, Robert H., Jr, Itoyama, Yasuto

“…Some cases of familial amyotrophic lateral sclerosis (ALS) are caused by mutations in the gene encoding cytosolic, copper-zinc superoxide dismutase (SOD1). We…”
Get full text