Search Results - "BROWN, G. B"
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1
Meiotic prophase length modulates Tel1-dependent DNA double-strand break interference
Published in PLoS genetics (01-03-2024)“…During meiosis, genetic recombination is initiated by the formation of many DNA double-strand breaks (DSBs) catalysed by the evolutionarily conserved…”
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2
Evidence for a new pathophysiological mechanism for coronary artery disease regression : Hepatic lipase-mediated changes in LDL density
Published in Circulation (New York, N.Y.) (20-04-1999)“…Small, dense LDL particles are associated with coronary artery disease (CAD) and predict angiographic changes in response to lipid-lowering therapy. Intensive…”
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3
Assessment of dioxin and dioxin-like compounds in mainstream smoke from selected US cigarette brands and reference cigarettes
Published in Food and chemical toxicology (01-05-2008)“…Mainstream cigarette smoke (MSS) from 12 US cigarette brands and two reference cigarettes was evaluated to determine concentrations of dioxins (i.e.,…”
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4
Pathogenesis of Porcine Reproductive and Respiratory Syndrome Virus-induced Increase in Susceptibility to Streptococcus suis Infection
Published in Veterinary pathology (01-03-2000)“…Eighty 3-week-old crossbred pigs were randomly assigned to six groups (13–14 pigs/group). Group 1 pigs served as uninoculated controls, group 2 pigs were…”
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5
Lipid lowering and plaque regression : new insights into prevention of plaque disruption and clinical events in coronary disease
Published in Circulation (New York, N.Y.) (01-06-1993)“…The consensus of evidence from angiographic trials demonstrates both coronary artery and clinical benefits from lowering of lipids by a variety of regimens…”
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6
Genetics of apolipoprotein B and apolipoprotein AI and premature coronary artery disease
Published in Journal of internal medicine (01-05-2006)“… Increased low‐density lipoprotein (LDL) and decreased high‐density lipoprotein cholesterol (HDL‐C) predict premature coronary artery disease, as do elevated…”
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7
Genetically determined apo B levels and peak LDL density predict angiographic response to intensive lipid‐lowering therapy
Published in Journal of internal medicine (01-04-2006)“… Objective: Lipid‐lowering therapy (LL‐Rx) reduces coronary artery disease (CAD) but the response varies amongst individuals. We investigated the…”
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Common Variants in the Promoter of the Hepatic Lipase Gene Are Associated With Lower Levels of Hepatic Lipase Activity, Buoyant LDL, and Higher HDL2 Cholesterol
Published in Arteriosclerosis, thrombosis, and vascular biology (01-11-1998)“…Increased hepatic lipase (HL) activity is associated with small, dense, low density lipoprotein (LDL) and low high density lipoprotein2 (HDL (2)) cholesterol…”
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9
Diet selectivity in a terrestrial forest invertebrate, the Auckland tree wētā, across three habitat zones
Published in Ecology and evolution (01-03-2018)“…Insects are important but overlooked components of forest ecosystems in New Zealand. For many insect species, information on foraging patterns and trophic…”
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10
Lumen diameter of normal human coronary arteries : influence of age, sex, anatomic variation, and left ventricular hypertrophy or dilation
Published in Circulation (New York, N.Y.) (01-07-1992)“…Precise knowledge of the expected "normal" lumen diameter at a given coronary anatomic location is a first step toward developing a quantitative estimate of…”
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11
Altered particle size distribution of apolipoprotein A-I-containing lipoproteins in subjects with coronary artery disease
Published in Journal of lipid research (01-03-1991)“…Plasma high density lipoproteins (HDL) can be separated into two subpopulations of apolipoprotein A-I-containing particles: those that also contain apoA-II…”
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12
Intimal fibromuscular hyperplasia at the venous anastomosis of PTFE grafts in hemodialysis patients: clinical, immunocytochemical. light and electron microscopic assessment
Published in Circulation (New York, N.Y.) (01-12-1989)“…Failure of arteriovenous communications used for chronic hemodialysis was studied during sequential 5-year periods after placement of either endogenous…”
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13
Effect of hepatic lipase on LDL in normal men and those with coronary artery disease
Published in Arteriosclerosis and thrombosis (01-02-1993)“…Hepatic triglyceride lipase (HL) is thought to play a role in the formation of low density lipoproteins (LDLs) from small very low density lipoproteins (VLDLs)…”
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14
Pathogenic Potential of Filoviruses: Role of Geographic Origin of Primate Host and Virus Strain
Published in The Journal of infectious diseases (01-10-1992)“…African filoviruses have caused outbreaks of fulminating hemorrhagic feveramong humans. In 1989, related filoviruses were isolated from cynomolgus monkeys…”
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Assignment of the human heart tetrodotoxin-resistant voltage-gated Na+ channel alpha-subunit gene (SCN5A) to band 3p21
Published in Cytogenetics and cell genetics (01-01-1995)“…The chromosomal location of SCN5A, the gene encoding the principal voltage-gated Na+ channel expressed in human heart, has been determined by three independent…”
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16
Comparison of immediate invasive, delayed invasive, and conservative strategies after tissue-type plasminogen activator : results of the thrombolysis in myocardial infarction (TIMI) phase II-A trial
Published in Circulation (New York, N.Y.) (01-05-1990)“…To assess the value and timing of percutaneous transluminal coronary angioplasty (PTCA) after thrombolytic therapy for acute myocardial infarction (AMI), 586…”
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17
Signaling antibodies complexed with adenovirus circumvent CAR and integrin interactions and improve gene delivery
Published in Gene therapy (01-09-2000)“…Current adenoviral (Ad) vectors cannot be targeted to specific cell types due to the widespread distribution of the Ad receptor (CAR). Moreover, CAR and/or…”
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Intrathoracic spatial location of specified coronary segments on the normal human heart: applications in quantitative arteriography, assessment of regional risk and contraction, and anatomic display
Published in Circulation (New York, N.Y.) (01-11-1988)“…The clinically important coronary segmental anatomy has been described in a format useful for quantitative analysis and standardized display. We have…”
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Simvastatin and Niacin, Antioxidant Vitamins, or the Combination for the Prevention of Coronary Disease
Published in The New England journal of medicine (29-11-2001)“…Patients with coronary disease and low high-density lipoprotein (HDL) cholesterol levels are at risk for coronary events. This study found that a combination…”
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20
Comparative Molecular Field Analysis of Hydantoin Binding to the Neuronal Voltage-Dependent Sodium Channel
Published in Journal of medicinal chemistry (06-05-1999)“…Comparative molecular field analysis (CoMFA), a 3-D QSAR technique, is widely used to correlate biological activity with observed differences in steric and…”
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