Search Results - "BROOME, M. R"

Understanding auditory verbal hallucinations: a systematic review of current evidence by Upthegrove, R., Broome, M. R., Caldwell, K., Ives, J., Oyebode, F., Wood, S. J.

“…Objective Auditory verbal hallucinations (AVHs) are core features of psychotic illness and remain significant in predicting poor outcome and risk. There has…”
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Delusion formation and reasoning biases in those at clinical high risk for psychosis by Broome, M. R., Johns, L. C., Valli, I., Woolley, J. B., Tabraham, P., Brett, C., Valmaggia, L., Peters, E., Garety, P. A., McGuire, P. K.

“…Cognitive models propose that faulty appraisal of anomalous experiences is critical in developing psychosis, particularly delusions. A data gathering bias may…”
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Economic impact of early intervention in people at high risk of psychosis by Valmaggia, L R, McCrone, P, Knapp, M, Woolley, J B, Broome, M R, Tabraham, P, Johns, L C, Prescott, C, Bramon, E, Lappin, J, Power, P, McGuire, P K

“…Despite the increasing development of early intervention services for psychosis, little is known about their cost-effectiveness. We assessed the…”
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Altered brain function directly related to structural abnormalities in people at ultra high risk of psychosis: Longitudinal VBM-fMRI study by Fusar-Poli, P, Broome, M.R, Woolley, J.B, Johns, L.C, Tabraham, P, Bramon, E, Valmaggia, L, Williams, S.C, McGuire, P

“…Abstract Background Several studies have indicated that people with prodromal signs of psychosis show alterations in the structure and function of the brain…”
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Spatial working memory in individuals at high risk for psychosis: Longitudinal fMRI study by Fusar-Poli, P, Broome, M.R, Matthiasson, P, Woolley, J.B, Johns, L.C, Tabraham, P, Bramon, E, Valmaggia, L, Williams, S.C, McGuire, P

“…Abstract Background Neurocognitive impairments in executive and mnemonic domains are already evident in the pre-psychotic phases. The longitudinal dynamic…”
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Prefrontal Function at Presentation Directly Related to Clinical Outcome in People at Ultrahigh Risk of Psychosis by FUSAR-POLI, P, BROOME, M. R, MCGUIRE, P, MATTHIASSON, P, WOOLLEY, J. B, MECHELLI, A, JOHNS, L. C, TABRAHAM, P, BRAMON, E, VALMAGGIA, L, WILLIAMS, S. C

“…The prodromal phase of psychosis is characterized by impaired executive function and altered prefrontal activation. The extent to which the severity of these…”
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Neural correlates of visuospatial working memory in the 'at-risk mental state' by Broome, M R, Fusar-Poli, P, Matthiasson, P, Woolley, J B, Valmaggia, L, Johns, L C, Tabraham, P, Bramon, E, Williams, S C R, Brammer, M J, Chitnis, X, Zelaya, F, McGuire, P K

“…Impaired spatial working memory (SWM) is a robust feature of schizophrenia and has been linked to the risk of developing psychosis in people with an at-risk…”
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Mood instability: Significance, definition and measurement by Broome, M. R., Saunders, K. E. A., Harrison, P. J., Marwaha, S.

“…Mood instability is common, and an important feature of several psychiatric disorders. We discuss the definition and measurement of mood instability, and…”
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Phenomenology as a resource for translational research in mental health: methodological trends, challenges and new directions by Ritunnano, R., Papola, D., Broome, M.R., Nelson, B.

“…This editorial reflects on current methodological trends in translational research in mental health. It aims to build a bridge between two fields that are…”
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Concepts of Mental Disorders in Trainee Clinical Psychologists by Read, R., Moberly, N. J., Salter, D., Broome, M. R.

“…Background The models of mental disorders held by all mental health professionals are implicit in their attitudes and inform all aspects of theory and…”
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Faulty Suppression of Irrelevant Material in Patients with Thought Disorder Linked to Attenuated Frontotemporal Activation by Brammer, M., Morris, R. G., McGuire, P. K., Arcuri, S. M., Andrew, C. M., Williams, S. C. R., Kircher, T. T. J., Broome, M. R., Giampietro, V., Amaro, E.

“…Formal thought disorder is a feature schizophrenia that manifests as disorganized, incoherent speech, and is associated with a poor clinical outcome. The…”
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Mood instability: Significance, definition andmeasurement by Broome, M R, Saunders K E A, Harrison, P J, Marwaha, S

“…Mood instability is common, and an important feature of several psychiatricdisorders. We discuss the definition and measurement of mood instability,and review…”
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Clinical Features and Treatment Outcomes of 41 Dogs with Sublingual Ectopic Thyroid Neoplasia by Broome, M.R, Peterson, M.E, Walker, J.R

“…BACKGROUND: Thyroid neoplasia is common in dogs, but there are few reports of dogs with ectopic, sublingual thyroid tumors. OBJECTIVES: To describe clinical…”
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Thyroid Cysts in Cats: A Retrospective Study of 40 Cases by Miller, M.L., Peterson, M.E., Randolph, J.F., Broome, M.R., Norsworthy, G.D., Rishniw, M.

“…Background Thyroid cysts are rare in cats and poorly documented. Objectives To report distinguishing clinical features and treatment responses of cats with…”
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Thalamic Glutamate Levels as a Predictor of Cortical Response During Executive Functioning in Subjects at High Risk for Psychosis by Fusar-Poli, P, Stone, J. M, Broome, M. R, Valli, I, Mechelli, A, McLean, M. A, Lythgoe, D. J, O'Gorman, R. L, Barker, G. J, McGuire, P. K

“…CONTEXT Alterations in glutamatergic neurotransmission and cerebral cortical dysfunction are thought to be central to the pathophysiology of psychosis, but the…”
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Misattributing speech and jumping to conclusions: A longitudinal study in people at high risk of psychosis by Winton-Brown, T.T, Broome, M.R, Allen, P, Valli, I, Howes, O, Garety, P.A, Johns, L.C, McGuire, P

“…Abstract Biases in cognition such as Jumping to Conclusions (JTC) and Verbal Self-Monitoring (VSM) are thought to underlie the formation of psychotic symptoms…”
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Delusional ideation, manic symptomatology and working memory in a cohort at clinical high-risk for psychosis: A longitudinal study by Broome, M.R, Day, F, Valli, I, Valmaggia, L, Johns, L.C, Howes, O, Garety, P, McGuire, P.K

“…Abstract We followed up a cohort ( n = 35) of clients with an “At Risk Mental State” (ARMS) for almost 2 years (mean 21.3 months). At baseline, these clients…”
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Neural correlates of movement generation in the 'at-risk mental state' by Broome, M. R., Matthiasson, P., Fusar-Poli, P., Woolley, J. B., Johns, L. C., Tabraham, P., Bramon, E., Valmaggia, L., Williams, S. C. R., Brammer, M. J., Chitnis, X., McGuire, P. K.

“…Broome MR, Matthiasson P, Fusar‐Poli P, Woolley JB, Johns LC, Tabraham P, Bramon E, Valmaggia L, Williams SCR, Brammer MJ, Chitnis X, McGuire PK. Neural…”
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Activation of the NO-cGMP signalling pathway depresses hippocampal synaptic transmission through an adenosine receptor-dependent mechanism by Broome, M R, Collingridge, G L, Irving, A J

“…Activation of the NO-cGMP pathway or adenosine receptors depresses reversibly synaptic transmission in the hippocampus. Here we demonstrate, using the…”
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Effects of acute antipsychotic treatment on brain activation in first episode psychosis: An fMRI study by Fusar-Poli, P, Broome, M.R, Matthiasson, P, Williams, S.C.R, Brammer, M, McGuire, P.K

“…Abstract This study aimed to assess the neurophysiological effects of acute atypical antipsychotic treatment on cognitive functioning in subjects presenting…”
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