Search Results - "BRONNER, Iraad F"

Quantitative insertion-site sequencing (QIseq) for high throughput phenotyping of transposon mutants by Bronner, Iraad F, Otto, Thomas D, Zhang, Min, Udenze, Kenneth, Wang, Chengqi, Quail, Michael A, Jiang, Rays H Y, Adams, John H, Rayner, Julian C

“…Genetic screening using random transposon insertions has been a powerful tool for uncovering biology in prokaryotes, where whole-genome saturating screens have…”
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Assembly of transgenic human P301S Tau is necessary for neurodegeneration in murine spinal cord by Macdonald, Jennifer A, Bronner, Iraad F, Drynan, Lesley, Fan, Juan, Curry, Annabelle, Fraser, Graham, Lavenir, Isabelle, Goedert, Michel

“…A pathological pathway leading from soluble monomeric to insoluble filamentous Tau is characteristic of many human neurodegenerative diseases, which also…”
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Comprehensive mRNA expression profiling distinguishes tauopathies and identifies shared molecular pathways by Bronner, Iraad F, Bochdanovits, Zoltán, Rizzu, Patrizia, Kamphorst, Wouter, Ravid, Rivka, van Swieten, John C, Heutink, Peter

“…Understanding the aetiologies of neurodegenerative diseases such as Alzheimer's disease (AD), Pick's disease (PiD), Progressive Supranuclear Palsy (PSP) and…”
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Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis by Zhang, Min, Wang, Chengqi, Otto, Thomas D, Oberstaller, Jenna, Liao, Xiangyun, Adapa, Swamy R, Udenze, Kenneth, Bronner, Iraad F, Casandra, Deborah, Mayho, Matthew, Brown, Jacqueline, Li, Suzanne, Swanson, Justin, Rayner, Julian C, Jiang, Rays H Y, Adams, John H

“…Severe malaria is caused by the apicomplexan parasite Despite decades of research, the distinct biology of these parasites has made it challenging to establish…”
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Genome-wide transposon screening and quantitative insertion site sequencing for cancer gene discovery in mice by Friedrich, Mathias J, Rad, Lena, Bronner, Iraad F, Strong, Alexander, Wang, Wei, Weber, Julia, Mayho, Matthew, Ponstingl, Hannes, Engleitner, Thomas, Grove, Carolyn, Pfaus, Anja, Saur, Dieter, Cadiñanos, Juan, Quail, Michael A, Vassiliou, George S, Liu, Pentao, Bradley, Allan, Rad, Roland

“…Friedrich et al. describe their toolkit for transposon-based insertional mutagenesis in mice for discovering cancer genes. Genome-wide transposon insertion…”
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A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer by Rad, Roland, Rad, Lena, Wang, Wei, Strong, Alexander, Ponstingl, Hannes, Bronner, Iraad F, Mayho, Matthew, Steiger, Katja, Weber, Julia, Hieber, Maren, Veltkamp, Christian, Eser, Stefan, Geumann, Ulf, Öllinger, Rupert, Zukowska, Magdalena, Barenboim, Maxim, Maresch, Roman, Cadiñanos, Juan, Friedrich, Mathias, Varela, Ignacio, Constantino-Casas, Fernando, Sarver, Aaron, ten Hoeve, Jelle, Prosser, Haydn, Seidler, Barbara, Bauer, Judith, Heikenwälder, Mathias, Metzakopian, Emmanouil, Krug, Anne, Ehmer, Ursula, Schneider, Günter, Knösel, Thomas, Rümmele, Petra, Aust, Daniela, Grützmann, Robert, Pilarsky, Christian, Ning, Zemin, Wessels, Lodewyk, Schmid, Roland M, Quail, Michael A, Vassiliou, George, Esposito, Irene, Liu, Pentao, Saur, Dieter, Bradley, Allan

“…Roland Rad and colleagues report development of a new conditional piggyBac transposition system for performing insertional mutagenesis screens in mice. They…”
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Improved Protocols for Illumina Sequencing by Bronner, Iraad F, Quail, Michael A, Turner, Daniel J, Swerdlow, Harold

“…In this unit, we describe a set of improvements that have been made to the standard Illumina protocols to make the sequencing process more reliable in a…”
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Best Practices for Illumina Library Preparation by Bronner, Iraad F, Quail, Michael A

“…In this unit, we describe a set of protocols and recommendations for Illumina library preparation. We review best practices in template quantitation methods;…”
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The ΔK280 Mutation in MAP tau Favors Exon 10 Skipping In Vivo by van Swieten, John C, Bronner, Iraad F, Azmani, Asma, Severijnen, Lies-Anne, Kamphorst, Wouter, Ravid, Rivka, Rizzu, Patrizia, Willemsen, Rob, Heutink, Peter

“…Tau mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) are associated with changes in alternative splicing of exon 10. The…”
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Progranulin mutations in Dutch familial frontotemporal lobar degeneration by BRONNER, Iraad F, RIZZU, Patrizia, SEELAAR, Harro, VAN MIL, Saskia E, ANARL, Burcu, AZMANI, Asma, DONKER KAAT, Laura, ROSSO, Sonia, HEUTINK, Peter, VAN SWIETEN, John C

“…Mutations in the progranulin (PGRN) gene have recently been identified in frontotemporal lobar degeneration with ubiquitin inclusions linked to chromosome…”
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The DJ-1L166P mutant protein associated with early onset Parkinson's disease is unstable and forms higher-order protein complexes by Macedo, Maria G., Anar, Burcu, Bronner, Iraad F., Cannella, Milena, Squitieri, Ferdinando, Bonifati, Vincenzo, Hoogeveen, André, Heutink, Peter, Rizzu, Patrizia

“…Parkinson's disease (PD) is a common neurodegenerative disorder that involves the selective degeneration of midbrain dopaminergic neurons. Recently DJ-1…”
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SARS-CoV-2 Testing in the Community: Testing Positive Samples with the TaqMan SARS-CoV-2 Mutation Panel To Find Variants in Real Time by Ashford, Fiona, Best, Angus, Dunn, Steven J, Ahmed, Zahra, Siddiqui, Henna, Melville, Jordan, Wilkinson, Samuel, Mirza, Jeremy, Cumley, Nicola, Stockton, Joanne, Ferguson, Jack, Wheatley, Lucy, Ratcliffe, Elizabeth, Casey, Anna, Plant, Tim, Quick, Joshua, Richter, Alex, Loman, Nicholas, McNally, Alan

“…Genome sequencing is a powerful tool for identifying SARS-CoV-2 variant lineages; however, there can be limitations due to sequence dropout when used to…”
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Uncovering the essential genome of the human malaria parasite Plasmodium falciparum by saturation mutagenesis by Zhang, Min, Wang, Chengqi, Otto, Thomas D., Oberstaller, Jenna, Liao, Xiangyun, Adapa, Swamy R., Udenze, Kenneth, Bronner, Iraad F., Cassandra, Deborah, Mayho, Matthew, Brown, Jacqueline, Li, Suzanne, Swanson, Justin, Rayner, Julian C., Jiang, Rays H. Y., Adams, John H.

“…Severe malaria is caused by the apicomplexan parasite Plasmodium falciparum. Despite decades of research the unique biology of these parasites has made it…”
Get full text

Quantitative insertion-site sequencing (QIseq) for high throughput phenotyping of transposon mutants by Bronner, Iraad F, Otto, Thomas D, Zhang, Min, Udenze, Kenneth, Wang, Chengqi, Quail, Michael A, Jiang, Rays HY, Adams, John H, Rayner, Julian C

“…Genetic screening using random transposon insertions has been a powerful tool for uncovering biology in prokaryotes, where whole-genome saturating screens have…”
Get full text

The DeltaK280 mutation in MAP tau favors exon 10 skipping in vivo by van Swieten, John C, Bronner, Iraad F, Azmani, Asma, Severijnen, Lies-Anne, Kamphorst, Wouter, Ravid, Rivka, Rizzu, Patrizia, Willemsen, Rob, Heutink, Peter

“…Tau mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) are associated with changes in alternative splicing of exon 10. The…”
Get full text

Progranulin mutations in Dutch familial frontotemporal lobar degeneration by Bronner, Iraad F, Rizzu, Patrizia, Seelaar, Harro, Van Mil, Saskia E, Anar, Burcu, Azmani, Asma, Kaat, Laura Donker, Rosso, Sonia, Heutink, Peter, Van Swieten, John C

“…Mutations in the progranulin (PGRN) gene have recently been identified in frontotemporal lobar degeneration with ubiquitin inclusions linked to chromosome…”
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The [Delta]K280 Mutation in MAP tau Favors Exon 10 Skipping In Vivo by van Swieten, John C, Bronner, Iraad F, Azmani, Asma, Lies-Anne Severijnen

“…Tau mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) are associated with changes in alternative splicing of exon 10. The…”
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P1-127: Distinguishing neurodegenerative disorders with tau pathology using MRNA expression microarrays by Bronner, Iraad F., Bochdanovits, Zoltan, Rizzu, Patrizia, Kamphorst, Wouter, Ravid, Rivka, van Swieten, John C., Heutink, Peter

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P3-333 Pathological characterization of two FTDP-17 patients carrying a G272V tau mutation by Bronner, Iraad F., ter Meulen, Bastiaan C., Kamphorst, Wouter, Ravid, Rivka, Heutink, Peter, van Swieten, John C.

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