Search Results - "BROMET, Norbert"

Development of an in Vitro Screening Model for the Biosynthesis of Acyl Glucuronide Metabolites and the Assessment of Their Reactivity toward Human Serum Albumin by BOLZE, Sebastien, BROMET, Norbert, GAY-FEUTRY, Croisine, MASSIERE, Frederic, BOULIEU, Roselyne, HULOT, Thierry

“…An in vitro screening model was developed to determine the reactivity of acyl glucuronide metabolites from carboxylic drugs. This assay is composed of two…”
Get full text

Biodistribution of polycyanoacrylate nanoparticles encapsulating doxorubicin by Matrix-Assisted Laser Desorption Ionization (MALDI) Mass Spectrometry Imaging (MSI) by Zandanel, Christelle, Legouffe, Raphael, Trochon-Joseph, Veronique, Tomezyk, Aurore, Gaudin, Mathieu, Bonnel, David, Stauber, Jonathan, Vasseur, Bérangère, Bromet, Norbert

“…Nanoparticles are widely used as carrier for the delivery of Active Principle Ingredients (API). From safety point of view, the fate of nanoparticles and API…”
Get full text

Characterization of human cytochrome P450 enzymes involved in the metabolism of cyamemazine by Arbus, Christophe, Benyamina, Amine, Llorca, Pierre-Michel, Baylé, Franck, Bromet, Norbert, Massiere, Frédéric, Garay, Ricardo P., Hameg, Ahcène

“…Recombinant human liver microsomal enzymes of the cytochrome P450 family (CYP1A2, CYP2A6, CYP3A4, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1) were used to…”
Get full text

A distribution study with (14)C-otilonium bromide in the rat: evidence for selective tropism for large intestine after oral administration by Evangelista, S, Cochet, P, Bromet, N, Criscuoli, M, Maggi, C A

“…The aim of this study was to determine the plasma levels and the tissue distribution of otilonium bromide, measured as total radioactivity, after oral…”
Get full text

Determination of melatonin in biological fluids in the presence of the melatonin agonist S 20098: comparison of immunological techniques and GC-MS methods by Simonin, Gilles, Bru, Laurence, Lelièvre, E, Jeanniot, Jean-Philippe, Bromet, Norbert, Walther, Bernard, Boursier-Neyret, Claire

“…Immunoassays were investigated for the determination of melatonin in biological samples in the presence of a naphthalenic structural analogue S 20098, which is…”
Get full text

A Distribution Study with 14C-Otilonium Bromide in The Rat: Evidence for Selective Tropism for Large Intestine after Oral Administration by Stefano Evangelista, Pascal Cochet, Norbert Bromet, Marco Criscuoli, Carlo Alberto Maggi

“…The aim of this study was to determine the plasma levels and the tissue distribution of otilonium bromide, measured as total radioactivity, after oral…”
Get full text

A General NMR Approach for the Structural Determination of Alkaloids:  Application to 3-β-Hydroxylupanine by Touché, André, Courtois, Didier, Frèche, Jean-Paul, Bromet, Norbert, Djedaïni-Pilard, Florence, Perly, Bruno, Guillaumet, Gérald, Rollin, Patrick

“…The structure of 3-β-hydroxylupanine, a major alkaloid isolated from the seeds of Lupinus mutabilis S., was unequivocally established through dedicated 1H and…”
Get full text

Pharmacokinetics of rilmenidine by Genissel, P, Bromet, N

“…Rilmenidine is a novel antihypertensive agent related to alpha 2-adrenoceptor agonist, used in the treatment of mild or moderate hypertension at the oral dose…”
Get more information

Pharmacokinetics of rilmenidine in healthy subjects by Genissel, Patrick, Bromet, Norbert, Fourtillan, Jean Bernard, Mignot, Alain, Albin, Henri

“…Rilmenidine is a novel α 2-adrenoceptor agonist, used in the treatment of mild or moderate hypertension at the oral dose of 1 mg once or twice daily. The…”
Get full text

A Dose Dumping Study with a Sustained-Release Formulation of Bunazosin (E1015) in Healthy Volunteers by Morishita, Nobumichi, Tomono, Yoshiro, Mainguy, Yves, Branagan, Paul, Bromet-Petit, Maguy, Bromet, Norbert

Get full text

Quantitative determination of almitrine in plasma by high-performance liquid chromatography by Parkhurst, G W, Bromet, N, MacLeod, C, Bachand, Jr, R T, Carson, P E

Get more information

Gas chromatographic-mass spectrometric assessment of the pharmacokinetics of amineptine and its main metabolite in volunteers with liver impairment by Tsaconas, C, Padieu, P, d'Athis, P, Mocaer, E, Bromet, N

“…A pharmacokinetic study of amineptine (Survector) and its C5 metabolite, resulting from a beta-oxidation of the heptanoic acid side-chain, was undertaken with…”
Get more information