Search Results - "BROKA, Chris A"

A new synthesis of 3-arylthioindoles as selective COX-2 inhibitors using PIFA by Campbell, Jeffrey A, Broka, Chris A, Gong, Leyi, Walker, Keith A.M, Wang, Jin-Hai

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Rational design of 6-methylsulfonylindoles as selective cyclooxygenase-2 inhibitors by Campbell, Jeffrey A., Bordunov, Viola, Broka, Chris A., Browner, Michelle F., Kress, James M., Mirzadegan, Tara, Ramesha, Chakk, Sanpablo, Bong F., Stabler, Russell, Takahara, Patricia, Villasenor, Armando, Walker, Keith A.M., Wang, Jin-Hai, Welch, Mary, Weller, Paul

“…The introduction of 3-arylmethyl, 3-aryloxy and 3-arylthio moieties into a 6-methylsulfonylindole framework using rational drug design led to potent, selective…”
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Preparation of 3-arylmethylindoles as selective COX-2 inhibitors by Campbell, Jeffrey A, Bordunov, Viola, Broka, Chris A, Dankwardt, John, Hendricks, Robert T, Kress, James M, Walker, Keith A.M, Wang, Jin-Hai

“…Graphic The 3-arylmethylation of indoles using TMSOTf/Et 3SiH with a wide variety of substituted benzaldehydes has been accomplished. Under these mild Lewis…”
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Reductive lithiation mediated anionic cyclizations and [2,3]-sigmatropic rearrangements by Broka, Chris A, Shen, Tong

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Synthetic studies on wortmannin and 11-desacetoxywortmannin by Broka, Chris A, Ruhland, Beatrice

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Anionic cyclizations of .alpha.-alkoxy lithiums. New, stereoselective routes to substituted tetrahydrofurans by Broka, Chris A, Lee, Wen Jee, Shen, Tong

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Total synthesis of debromoaplysiatoxin and aplysiatoxin by Park, Pyeong Uk, Broka, Chris A, Johnson, Bruce F, Kishi, Yoshito

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A short total synthesis of (.+-.)-gephyrotoxin-223AB by Broka, Chris A, Eng, Kan K

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Amino acid derived sulfonamide hydroxamates as inhibitors of procollagen C-proteinase. Part 2: Solid-phase optimization of side chains by DANKWARDT, Sharon M, ABBOT, Sarah C, BROKA, Chris A, MARTIN, Robert L, CHAN, Christine S, SPRINGMAN, Eric B, VAN WART, Harold E, WALKER, Keith A. M

“…Optimization of the amino acid side chain and the N-alkyl group of the sulfonamide of amino acid derived sulfonamide hydroxamates is discussed. The solid-phase…”
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Total synthesis of (-)-pseudopterosin A by Broka, Chris A, Chan, Samantha, Peterson, Barry

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Synthetic studies on thyrsiferol. Elaboration of the bromotetrahydropyran ring by Broka, Chris A, Lin, Yi Tsong

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Photorearrangements of carbomethoxy-substituted cyclohexadienones in neutral media by Broka, Chris A

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Aziridinium cation mediated cyclizations. New routes to the morphinan ring system by Broka, Chris A, Gerlits, John F

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Corrigendum to “Preparation of 3-arylmethylindoles as selective COX-2 inhibitors”: [Tetrahedron Lett. 45 (2004) 3793] by Campbell, Jeffrey A, Bordunov, Viola, Broka, Chris A, Dankwardt, John, Hendricks, Robert T, Kress, James M, Walker, Keith A.M, Wang, Jin-Hai

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2-aryl-indolyl maleimides - novel and potent inhibitors of protein kinase C by Hendricks, Robert T., Sherman, Dan, Strulovici, Berta, Broka, Chris A.

“…A new class of protein kinase C (PKC) inhibitors is described. These inhibitors were derived from the familiar bis-indolyl maleimide series of inhibitors…”
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