Search Results - "BRODSKYN, C"

Role of Sand Fly Saliva in Human and Experimental Leishmaniasis: Current Insights by Andrade, B.B, de Oliveira, C.I, Brodskyn, C.I, Barral, A, Barral-Netto, M

“…Leishmaniases are wide spread diseases transmitted to their vertebrate host by infected sand fly. The saliva from these arthropods contains a vast repertoire…”
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Testing of Four Leishmania Vaccine Candidates in a Mouse Model of Infection with Leishmania (Viannia) braziliensis, the Main Causative Agent of Cutaneous Leishmaniasis in the New World by Salay, G, Dorta, M L, Santos, N M, Mortara, R A, Brodskyn, C, Oliveira, C I, Barbiéri, C L, Rodrigues, M M

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Glycoinositolphospholipids from Trypanosoma cruzi Interfere with Macrophages and Dendritic Cell Responses by Brodskyn, Claudia, Patricio, Julie, Oliveira, Rubem, Lobo, Lucas, Arnholdt, Andrea, Mendonça-Previato, Lucia, Barral, Aldina, Barral-Netto, Manoel

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Differences in Gamma Interferon Production In Vitro Predict the Pace of the In Vivo Response to Leishmania amazonensis in Healthy Volunteers by POMPEU, M. M. L, BRODSKYN, C, TEIXEIRA, M. J, CLARENCIO, J, VAN WEYENBERG, J, COELHO, I. C. B, CARDOSO, S. A, BARRAL, A, BARRAL-NETTO, M

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Influence of Costimulatory Molecules on Immune Response to Leishmania major by Human Cells In Vitro by BRODSKYN, Claudia I, DEKREY, Gregory K, TITUS, Richard G

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A dhfr-ts-Leishmania major Knockout Mutant Cross-protects against Leishmania amazonensis by Veras, P, Brodskyn, C, Balestieri, F, Freitas, L d, Ramos, A, Queiroz, A, Barral, A, Beverley, S, Barral-Netto, M

“…E10-5A3 is a dhfr-ts- Leishmania major double knockout auxotrophic shown previously to induce substantial protection against virulent L. major infection in…”
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Lutzomyia longipalpis Salivary Gland Homogenate Impairs Cytokine Production and Costimulatory Molecule Expression on Human Monocytes and Dendritic Cells by COSTA, Dirceu J, FAVALI, Cecilia, BRODSKYN, Claudia Ida, CLARENCIO, Jorge, AFONSO, Lilian, CONCEICAO, Viviane, MIRANDA, José Carlos, TITUS, Richard G, VALENZUELA, Jesus, BARRAL-NETTO, Manoel, BARRAL, Aldina

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Virulent or avirulent (dhfr‐ts−) Leishmania major elicit predominantly a type‐1 cytokine response by human cells in vitro by BRODSKYN, C, BEVERLEY, S. M, TITUS, R. G

“…In this study we have compared the immune response of normal human cells cultured in vitro to two virulent strains of Leishmania major (CC1 and LV39), and to…”
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Parasite-driven in vitro human lymphocyte cytotoxicity against autologous infected macrophages from mucosal leishmaniasis by Brodskyn, CI, Barral, A, Boaventura, V, Carvalho, E, Barral-Netto, M

“…Parasite-specific cytotoxicity in human leishmaniasis was evaluated in an autologous system. PBL from cutaneous leishmaniasis (CL) or mucosal leishmaniasis…”
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Human_Leishmaniasis@cytokines.bahia.br by Barral-Netto, M., Brodskyn, C., Carvalho, E.M., Barral, A.

“…The cell-mediated immune response is critical in the resistance to and recovery from leishmaniasis. Cytokines are central elements in mounting an immune…”
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Cytotoxicity in patients with different clinical forms of Chagas' disease by BRODSKYN, C. I., BARRAL, A., BULHÕES, M. A., SOUTO, T., MACHADO, W. C., BARRAL‐NETTO, M.

“…There are few studies on cell‐mediated cytotoxicity in human Chagas' disease. In the present study, we evaluated peripheral blood mononuclear cell (PBMC)…”
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A new liquid medium without blood and serum for culture of hemoflagellates by Sadigursky, M, Brodskyn, C I

“…A liquid medium without blood or serum was developed for cultivation of hemoflagellates. To a basic LIT medium containing liver infusion broth and tryptose, a…”
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IgG subclasses responsible for immune clearance in mice infected with Trypanosoma cruzi by Brodskyn, C I, Silva, A M, Takehara, H A, Mota, I

“…To examine the role of different immunoglobulin subclasses in the immune clearance of Trypanosoma cruzi, mice containing bloodstream trypomastigotes were…”
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Interactions with apoptotic but not with necrotic neutrophils increase parasite burden in human macrophages infected with Leishmania amazonensis by Afonso, Lilian, Borges, Valéria M, Cruz, Heloísa, Ribeiro-Gomes, Flávia L, DosReis, George A, Dutra, Alberto Noronha, Clarêncio, Jorge, de Oliveira, Camila I, Barral, Aldina, Barral-Netto, Manoel, Brodskyn, Cláudia I

“…Neutrophils are involved in the initial steps of most responses to pathogens. In the present study, we evaluated the effects of the interaction of apoptotic…”
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Balance of IL-10 and interferon-gamma plasma levels in human visceral leishmaniasis: implications in the pathogenesis by Caldas, Arlene, Favali, Cecília, Aquino, Dorlene, Vinhas, Vera, van Weyenbergh, Johan, Brodskyn, Cláudia, Costa, Jackson, Barral-Netto, Manoel, Barral, Aldina

“…Leishmaniasis remains a serious public health problem in several parts of the developing world. Effective prophylactic measurements are hampered by imprecise…”
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Towards development of novel immunization strategies against leishmaniasis using PLGA nanoparticles loaded with kinetoplastid membrane protein-11 by Santos, Diego M, Carneiro, Marcia W, de Moura, Tatiana R, Fukutani, Kiyoshi, Clarencio, Jorge, Soto, Manuel, Espuelas, Socorro, Brodskyn, Claudia, Barral, Aldina, Barral-Netto, Manoel, de Oliveira, Camila I

“…Vaccine development has been a priority in the fight against leishmaniases, which are vector-borne diseases caused by Leishmania protozoa. Among the different…”
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Leishmania amazonensis infection impairs differentiation and function of human dendritic cells by Favali, Cecilia, Tavares, Natália, Clarêncio, Jorge, Barral, Aldina, Barral‐Netto, Manoel, Brodskyn, Claudia

“…Dendritic cells (DCs) are of utmost importance in initiating an immune response and may also function as targets for pathogens. The presence of pathogens…”
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Antigenic cross-reactivity of venoms obtained from snakes of genus Bothrops by da Silva, A M, Lima, M R, Nishikawa, A K, Brodskyn, C I, dos Santos, M C, Furtado, M F, da Silva, W D, Mota, I

“…Antigenic cross-reactivity was studied among the components of venoms from nine species of the genus Bothrops using species-specific antivenoms. Sera titration…”
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Toward a Novel Experimental Model of Infection To Study American Cutaneous Leishmaniasis Caused by Leishmania braziliensis by de Moura, Tatiana R, Novais, Fernanda O, Oliveira, Fabiano, Clarêncio, Jorge, Noronha, Almério, Barral, Aldina, Brodskyn, Claudia, de Oliveira, Camila I

“…Leishmania spp. cause a broad spectrum of diseases collectively known as leishmaniasis. Leishmania braziliensis is the main etiological agent of American…”
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Saliva from Lutzomyia longipalpis Induces CC Chemokine Ligand 2/Monocyte Chemoattractant Protein-1 Expression and Macrophage Recruitment by Teixeira, Clarissa R, Teixeira, Maria Jania, Gomes, Regis B. B, Santos, Claire S, Andrade, Bruno B, Raffaele-Netto, Imbroinise, Silva, Joao S, Guglielmotti, Angelo, Miranda, Jose C, Barral, Aldina, Brodskyn, Claudia, Barral-Netto, Manoel

“…Saliva of bloodfeeding arthropods has been incriminated in facilitating the establishment of parasite in their host. We report on the leukocyte chemoattractive…”
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