Search Results - "BROADLEY, Simon A"

Vitamin D for the treatment of multiple sclerosis: a meta-analysis by McLaughlin, Laurie, Clarke, Laura, Khalilidehkordi, Elham, Butzkueven, Helmut, Taylor, Bruce, Broadley, Simon A.

“…Objective There is an association between latitude, relative vitamin D deficiency and risk of multiple sclerosis (MS), and an association between vitamin D and…”
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Epidemiology of Neuromyelitis Optica Spectrum Disorder and Its Prevalence and Incidence Worldwide by Hor, Jyh Yung, Asgari, Nasrin, Nakashima, Ichiro, Broadley, Simon A., Leite, M. Isabel, Kissani, Najib, Jacob, Anu, Marignier, Romain, Weinshenker, Brian G., Paul, Friedemann, Pittock, Sean J., Palace, Jacqueline, Wingerchuk, Dean M., Behne, Jacinta M., Yeaman, Michael R., Fujihara, Kazuo

“…Neuromyelitis optica spectrum disorder (NMOSD) is an uncommon inflammatory disease of the central nervous system, manifesting clinically as optic neuritis,…”
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The role of alemtuzumab in the development of secondary autoimmunity in multiple sclerosis: a systematic review by Jimenez-Sanchez, Sofia, Maksoud, Rebekah, Eaton-Fitch, Natalie, Marshall-Gradisnik, Sonya, Broadley, Simon A

“…Background Secondary autoimmune disease (SAID) in the context of alemtuzumab treatment is one of the main safety concerns that may arise following…”
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Efficacy of Face-to-Face Delivered Cognitive Behavioral Therapy in Improving Health Status of Patients With Insomnia: A Meta-Analysis by Xu, Dawei, Cardell, Elizabeth, Broadley, Simon A, Sun, Jing

“…Face-to-face cognitive behavioral therapy (CBT) is one of the most widely used non-pharmacological treatment approaches for insomnia. The aim of this study is…”
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The association between disability progression, relapses, and treatment in early relapse onset MS: an observational, multi-centre, longitudinal cohort study by Fuh-Ngwa, Valery, Charlesworth, Jac C., Zhou, Yuan, van der Mei, Ingrid, Melton, Phillip E., Broadley, Simon A., Ponsonby, Anne-Louise, Simpson-Yap, Steve, Lechner-Scott, Jeannette, Taylor, Bruce V.

“…The indirect contribution of multiple sclerosis (MS) relapses to disability worsening outcomes, and vice-versa, remains unclear. Disease modifying therapies…”
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AQP4 Antibody Assay Sensitivity Comparison in the Era of the 2015 Diagnostic Criteria for NMOSD by Prain, Kerri, Woodhall, Mark, Vincent, Angela, Ramanathan, Sudarshini, Barnett, Michael H., Bundell, Christine S., Parratt, John D. E., Silvestrini, Roger A., Bukhari, Wajih, Brilot, Fabienne, Waters, Patrick, Broadley, Simon A.

“…We have compared five different assays for antibodies to aquaporin-4 in 181 cases of suspected Neuromyelitis optica spectrum disorders (NMOSD) and 253 controls…”
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Ensemble machine learning identifies genetic loci associated with future worsening of disability in people with multiple sclerosis by Fuh-Ngwa, Valery, Zhou, Yuan, Melton, Phillip E., van der Mei, Ingrid, Charlesworth, Jac C., Lin, Xin, Zarghami, Amin, Broadley, Simon A., Ponsonby, Anne-Louise, Simpson-Yap, Steve, Lechner-Scott, Jeannette, Taylor, Bruce V.

“…Limited studies have been conducted to identify and validate multiple sclerosis (MS) genetic loci associated with disability progression. We aimed to identify…”
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Molecular pathogenesis of neuromyelitis optica by Bukhari, Wajih, Barnett, Michael H, Prain, Kerri, Broadley, Simon A

“…Neuromyelitis optica (NMO) is a rare autoimmune disorder, distinct from multiple sclerosis, causing inflammatory lesions in the optic nerves and spinal cord…”
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SUNCT and SUNA: Clinical features and medical treatment by Williams, Max H, Broadley, Simon A

“…Abstract Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) and short-lasting unilateral neuralgiform headache…”
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What do effective treatments for multiple sclerosis tell us about the molecular mechanisms involved in pathogenesis? by Buzzard, Katherine A, Broadley, Simon A, Butzkueven, Helmut

“…Multiple sclerosis is a potentially debilitating disease of the central nervous system. A concerted program of research by many centers around the world has…”
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A transcription factor map as revealed by a genome-wide gene expression analysis of whole-blood mRNA transcriptome in multiple sclerosis by Riveros, Carlos, Mellor, Drew, Gandhi, Kaushal S, McKay, Fiona C, Cox, Mathew B, Berretta, Regina, Vaezpour, S Yahya, Inostroza-Ponta, Mario, Broadley, Simon A, Heard, Robert N, Vucic, Stephen, Stewart, Graeme J, Williams, David W, Scott, Rodney J, Lechner-Scott, Jeanette, Booth, David R, Moscato, Pablo

“…Several lines of evidence suggest that transcription factors are involved in the pathogenesis of Multiple Sclerosis (MS) but complete mapping of the whole…”
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Multiple sclerosis: from molecules to treatment by Broadley, Simon A

“…The treatment of multiple sclerosis has been radically transformed over the past 20 years and this special issue of IJMS, focusing on the molecular aspects of…”
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Magnetic resonance imaging in neuromyelitis optica spectrum disorder by Clarke, Laura, Arnett, Simon, Lilley, Kate, Liao, Jacky, Bhuta, Sandeep, Broadley, Simon A

“…Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory disease of the central nervous system (CNS) associated with antibodies to aquaporin‐4 (AQP4),…”
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Worldwide Incidence and Prevalence of Neuromyelitis Optica: A Systematic Review by Papp, Viktoria, Magyari, Melinda, Aktas, Orhan, Berger, Thomas, Broadley, Simon A., Cabre, Philippe, Jacob, Anu, Kira, Jun-ichi, Leite, Maria Isabel, Marignier, Romain, Miyamoto, Katsuichi, Palace, Jacqueline, Saiz, Albert, Sepulveda, Maria, Sveinsson, Olafur, Illes, Zsolt

“…Since the last epidemiologic review of neuromyelitis optica/neuromyelitis optica spectrum disorder (NMO/NMOSD), 22 additional studies have been conducted. We…”
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Long-term outcomes of ADEM-like and tumefactive presentations of CNS demyelination: a case-comparison analysis by Arnett, Simon V., Prain, Kerri, Ramanathan, Sudarshini, Bhuta, Sandeep, Brilot, Fabienne, Broadley, Simon A.

“…A minority of initial multiple sclerosis (MS) presentations clinically or radiologically resemble other central nervous system (CNS) pathologies, acute…”
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Modelling genetic susceptibility to multiple sclerosis with family data by O'Gorman, Cullen, Lin, Rui, Stankovich, James, Broadley, Simon A

“…A genetic contribution to susceptibility is well established in multiple sclerosis (MS) and 57 associated genetic loci have been identified. We have undertaken…”
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Incidence and prevalence of NMOSD in Australia and New Zealand by Bukhari, Wajih, Prain, Kerri M, Waters, Patrick, Woodhall, Mark, O‘Gorman, Cullen M, Clarke, Laura, Silvestrini, Roger A, Bundell, Christine S, Abernethy, David, Bhuta, Sandeep, Blum, Stefan, Boggild, Mike, Boundy, Karyn, Brew, Bruce J, Brown, Matthew, Brownlee, Wallace J, Butzkueven, Helmut, Carroll, William M, Chen, Celia, Coulthard, Alan, Dale, Russell C, Das, Chandi, Dear, Keith, Fabis-Pedrini, Marzena J, Fulcher, David, Gillis, David, Hawke, Simon, Heard, Robert, Henderson, Andrew P D, Heshmat, Saman, Hodgkinson, Suzanne, Jimenez-Sanchez, Sofia, Killpatrick, Trevor, King, John, Kneebone, Christopher, Kornberg, Andrew J, Lechner-Scott, Jeannette, Lin, Ming-Wei, Lynch, Christpher, Macdonell, Richard, Mason, Deborah F, McCombe, Pamela A, Pender, Michael P, Pereira, Jennifer A, Pollard, John D, Reddel, Stephen W, Shaw, Cameron, Spies, Judith, Stankovich, James, Sutton, Ian, Vucic, Steve, Walsh, Michael, Wong, Richard C, Yiu, Eppie M, Barnett, Michael H, Kermode, Allan G, Marriott, Mark P, Parratt, John D E, Slee, Mark, Taylor, Bruce V, Willoughby, Ernest, Wilson, Robert J, Vincent, Angela, Broadley, Simon A

“…ObjectivesWe have undertaken a clinic-based survey of neuromyelitis optica spectrum disorders (NMOSDs) in Australia and New Zealand to establish incidence and…”
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Long-term disability trajectories in multiple sclerosis: a group-based trajectory analysis of the AusLong cohort by Zarghami, Amin, Hussain, Mohammad Akhtar, van der Mei, Ingrid, Simpson-Yap, Steve, Ponsonby, Anne-Louise, Lechner-Scott, Jeanette, Broadley, Simon A, Lucas, Robyn M, Zhou, Yuan, Lin, Xin, Investigator Group, AusLong, Taylor, Bruce V

“…BackgroundPrevious natural history studies highlighted a consistent heterogeneity of disability trajectories among individuals with primary or secondary…”
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Homozygous frameshift mutation of SPG11 as a cause of progressive flaccid paralysis, ataxia and dysphagia by Lilley, Kate, Bhuta, Sandeep, Sabet, Arman, Broadley, Simon A

“…•Autosomal recessive HSP (ARHSP) diagnosed at age 44, predominant lower motor neuron findings, lack of clinical spasticity.•Novel SPG11 mutation.•Atypical for…”
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Effects of Cannabis in Parkinson's Disease: A Systematic Review and Meta-Analysis by Urbi, Berzenn, Corbett, Joel, Hughes, Ian, Owusu, Maame Amma, Thorning, Sarah, Broadley, Simon A, Sabet, Arman, Heshmat, Saman

“…The legalization of cannabis in many countries has allowed many Parkinson's disease (PD) patients to turn to cannabis as a treatment. As such there is a…”
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