Search Results - "BRIX, Thomas"

Twin studies as a model for exploring the aetiology of autoimmune thyroid disease by Brix, Thomas Heiberg, Hegedüs, Laszlo

“…Summary Twins are an important resource for evaluating the relative contribution of genetic and environmental factors in determining a phenotype. During the…”
Get full text

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and thyroid disease. An update by Brix, Thomas H., Hegedüs, Laszlo

“…Purpose of review Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is associated with excess morbidity and mortality in patients with…”
Get full text

Risk and course of SARS-CoV-2 infection in patients treated for hypothyroidism and hyperthyroidism by Brix, Thomas H, Hegedüs, Laszlo, Hallas, Jesper, Lund, Lars C

Get full text

A critical review and meta-analysis of the association between overt hyperthyroidism and mortality by Brandt, Frans, Green, Anders, Hegedüs, Laszlo, Brix, Thomas H

“…BackgroundOvert hyperthyroidism has been associated with cardiac arrhythmias, hypercoagulopathy, stroke, and pulmonary embolism, all of which may increase…”
Get full text

Increased risk of dementia in hypothyroidism: A Danish nationwide register‐based study by Thvilum, Marianne, Brandt, Frans, Lillevang‐Johansen, Mads, Folkestad, Lars, Brix, Thomas H., Hegedüs, Laszlo

“…Objective Globally, the prevalence of individuals with dementia is increasing, and identification of risk factors is of paramount interest. Using…”
Get full text

Death by unnatural causes, mainly suicide, is increased in patients with Hashimoto’s thyroiditis. A nationwide Danish register study by Heiberg Brix, Thomas, Ferløv-Schwensen, Charlotte, Thvilum, Marianne, Hegedüs, Laszlo

“…Purpose Hashimoto’s thyroiditis (HT) is associated with excess psychiatric in addition to reduced quality of life. However, little is known about risk of…”
Get full text

Excess Mortality in Patients Diagnosed With Hypothyroidism: A Nationwide Cohort Study of Singletons and Twins by Thvilum, Marianne, Brandt, Frans, Almind, Dorthe, Christensen, Kaare, Hegedüs, Laszlo, Brix, Thomas Heiberg

“…Background: Although hypothyroidism is associated with increased morbidity, an association with increased mortality is still debated. Our objective was to…”
Get full text

Low Serum Thyrotropin Level and Duration of Suppression as a Predictor of Major Osteoporotic Fractures—The OPENTHYRO Register Cohort by Abrahamsen, Bo, Jørgensen, Henrik L, Laulund, Anne Sofie, Nybo, Mads, Brix, Thomas H, Hegedüs, Laszlo

“…ABSTRACT The relationship between thyrotoxicosis and osteoporotic fractures remains controversial, particularly in men. Register‐based cohort study including…”
Get full text

2021 European Thyroid Association Guidelines for the Management of Iodine-Based Contrast Media-Induced Thyroid Dysfunction by Bednarczuk, Tomasz, Brix, Thomas H., Schima, Wolfgang, Zettinig, Georg, Kahaly, George J.

“…Given the fact that a large number of radiological examinations using iodine-based contrast media (ICM) are performed in everyday practice, clinicians should…”
Get full text

European Thyroid Association (ETA) and Thyroid Federation International (TFI) Joint Position Statement on the Interchangeability of Levothyroxine Products in EU Countries by Fliers, Eric, Demeneix, Barbara, Bhaseen, Ashok, Brix, Thomas H.

“…Several European countries have seen major health issues after a switch from one levothyroxine brand to another, as well as following the introduction of…”
Get full text

The Excess Risk of Major Osteoporotic Fractures in Hypothyroidism Is Driven by Cumulative Hyperthyroid as Opposed to Hypothyroid Time: An Observational Register‐Based Time‐Resolved Cohort Analysis by Abrahamsen, Bo, Jørgensen, Henrik L., Laulund, Anne Sofie, Nybo, Mads, Bauer, Doug C., Brix, Thomas H., Hegedüs, Laszlo

“…ABSTRACT The long‐term relationship between hypothyroidism and fracture risk is challenging to dissect because of the modifying influence of subsequent…”
Get full text

Subclinical Hyperthyroidism by Hegedüs, Laszlo, Brix, Thomas H, Lillevang-Johansen, Mads

Get full text

Excess Mortality in Hyperthyroidism: The Influence of Preexisting Comorbidity and Genetic Confounding: A Danish Nationwide Register-Based Cohort Study of Twins and Singletons by Brandt, Frans, Almind, Dorthe, Christensen, Kaare, Green, Anders, Brix, Thomas Heiberg, Hegedüs, Laszlo

“…Context: Hyperthyroidism is associated with severe comorbidity, such as stroke, and seems to confer increased mortality. However, it is unknown whether this…”
Get full text

Epigenome-wide Association Study Shows Differential DNA Methylation of MDC1, KLF9, and CUTA in Autoimmune Thyroid Disease by Lafontaine, Nicole, Shore, Christopher J, Campbell, Purdey J, Mullin, Benjamin H, Brown, Suzanne J, Panicker, Vijay, Dudbridge, Frank, Brix, Thomas H, Hegedüs, Laszlo, Wilson, Scott G, Bell, Jordana T, Walsh, John P

“…Autoimmune thyroid disease (AITD) includes Graves disease (GD) and Hashimoto disease (HD), which often run in the same family. AITD etiology is incompletely…”
Get full text

Treatment of Hyperthyroidism Reduces Systemic Oxidative Stress, as Measured by Markers of RNA and DNA Damage by Larsen, Camilla B, Riis, Kamilla R, Winther, Kristian H, Larsen, Emil L, Ellervik, Christina, Hegedüs, Laszlo, Brix, Thomas H, Poulsen, Henrik E, Bonnema, Steen J

“…Abstract Background Whole-body oxidative stress can be estimated by the urine excretion of oxidized guanosine species, 8-oxo-7,8-dihydroguanosine (8-oxoGuo)…”
Get full text

A review of the evidence for and against increased mortality in hypothyroidism by Thvilum, Marianne, Brandt, Frans, Brix, Thomas H., Hegedüs, Laszlo

“…Hypothyroidism has been linked with cardiac dysfunction, atherosclerosis, hypertension and coagulopathy, and this increased morbidity might be expected to…”
Get full text

Mycophenolate plus methylprednisolone versus methylprednisolone alone in active, moderate-to-severe Graves' orbitopathy (MINGO): a randomised, observer-masked, multicentre trial by Kahaly, George J, Riedl, Michaela, König, Jochem, Pitz, Susanne, Ponto, Katharina, Diana, Tanja, Kampmann, Elena, Kolbe, Elisa, Eckstein, Anja, Moeller, Lars C, Führer, Dagmar, Salvi, Mario, Curro, Nicola, Campi, Irene, Covelli, Danila, Leo, Marenza, Marinò, Michele, Menconi, Francesca, Marcocci, Claudio, Bartalena, Luigi, Perros, Petros, Wiersinga, Wilmar M, Ayvaz, Göksun, Baldeschi, Lelio, Boborides, Kostas, Boschi, Antonella, Brix, Thomas H, Clarke, Lucy, Dayan, Colin, Daumerie, Chantal, Dickinson, A Jane, Fichter, Nicole, Hegedüs, Laszlo, Konuk, Onur, Krassas, Gerassimos E, Lane, Carol, Lazarus, John, Morris, Dan S, Mourits, Maarten, Nardi, Marco, Neoh, Chris, Orgiazzi, Jacques, Pearce, Simon H S, von Arx, Georg, Zarkovic, Milos

“…European guidelines recommend intravenous methylprednisolone as first-line treatment for active and severe Graves' orbitopathy; however, it is common for…”
Get full text

Methimazole and risk of acute pancreatitis by Brix, Thomas H, Lund, Lars C, Henriksen, Daniel P, Folkestad, Lars, Bonnema, Steen J, Hallas, Jesper, Hegedüs, Laszlo

Get full text

Mortality in Graves’ orbitopathy is increased and influenced by gender, age and pre-existing morbidity: a nationwide Danish register study by Schwensen, Charlotte F, Brandt, Frans, Hegedüs, Laszlo, Brix, Thomas H

“…Introduction It is unclear whether the excess mortality associated with Graves’ disease differs between individuals with Graves’ orbitopathy (GO) or without…”
Get full text

Frequency and characteristics of immune-related thyroid adverse events in patients with resected stage III/IV melanoma treated with adjuvant PD-1 inhibitors: a national cohort study by Christensen, Stine K., Winther, Mette L., Laursen, Ida J., Madsen, Freja S., Brink, Carsten, Brix, Thomas H., Ellebaek, Eva, Svane, Inge Marie, Hansen, Frederikke S., Haslund, Charlotte, Laursen, Olivia K., Schmidt, Henrik, Larsen, Ida D., Bastholt, Lars, Ruhlmann, Christina H.

“…Purpose Immune-related thyroid adverse events (irTAEs) occur frequently following immune checkpoint inhibitor (ICI) therapy. The purpose of this study is to…”
Get full text