Search Results - "BRISSOT, P"

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    The origin and spread of the HFE-C282Y haemochromatosis mutation by DISTANTE, S, ROBSON, K. J. H, GRAHAM-CAMPBELL, J, ARNAIZ-VILLENA, A, BRISSOT, P, WORWOOD, Mark

    Published in Human genetics (01-09-2004)
    “…The mutation responsible for most cases of genetic haemochromatosis in Europe (HFE C282Y) appears to have been originated as a unique event on a chromosome…”
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    A new mutation in the hepcidin promoter impairs its BMP response and contributes to a severe phenotype in HFE related hemochromatosis by Island, Marie-Laure, Jouanolle, Anne-Marie, Mosser, Annick, Deugnier, Yves, David, Veronique, Brissot, Pierre, Loreal, Olivier

    Published in Haematologica (Roma) (01-05-2009)
    “…1 Inserm U522, IFR140; University of Rennes 1 2 Molecular Genetic Department 3 French National Centre for Rare Genetic Iron Overload Diseases 4 Liver Disease…”
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    Insulin resistance–associated hepatic iron overload by Mendler, Michel-Henry, Turlin, Bruno, Moirand, Romain, Jouanolle, Anne-Marie, Sapey, Thierry, Guyader, Dominique, le Gall, Jean-Yves, Brissot, Pierre, David, Véronique, Deugnier, Yves

    Published in Gastroenterology (New York, N.Y. 1943) (01-11-1999)
    “…Background & Aims: Hepatic iron overload has been reported in various metabolic conditions, including the insulin-resistance syndrome (IRS) and nonalcoholic…”
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    Hereditary hemochromatosis: presenting manifestations and diagnostic delay by Gasser, B, Courtois, F, Hojjat-Assari, S, Sauleau, E A, Buffet, C, Brissot, P

    Published in La revue de medecine interne (01-03-2014)
    “…Hereditary hemochromatosis is characterized by an excessive absorption and progressive accumulation of iron in the liver, the pancreas, the heart, and the…”
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    Noninvasive prediction of fibrosis in C282Y homozygous hemochromatosis by Guyader, Dominique, Jacquelinet, Christian, Moirand, Romain, Turlin, Bruno, Mendler, Michel H., Chaperon, Jacques, David, Véronique, Brissot, Pierre, Adams, Paul, Deugnier, Yves

    Published in Gastroenterology (New York, N.Y. 1943) (01-10-1998)
    “…Background & Aims: The diagnosis of hemochromatosis is now possible for C282Y homozygous patients using noninvasive molecular genetic tests. The aim of this…”
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    Indication of liver transplantation in severe alcoholic liver cirrhosis: quantitative evaluation and optimal timing by Veldt, Bartholomeus Johannes, Lainé, Fabrice, Guillygomarc'h, Anne, Lauvin, Laurence, Boudjema, Karim, Messner, Michel, Brissot, Pierre, Deugnier, Yves, Moirand, Romain

    Published in Journal of hepatology (2002)
    “…Background/Aims : The aim of our study was to evaluate the proportion of patients with severe alcoholic cirrhosis who would need orthotopic liver…”
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    Duodenal mRNA expression of iron related genes in response to iron loading and iron deficiency in four strains of mice by Dupic, F, Fruchon, S, Bensaid, M, Loreal, O, Brissot, P, Borot, N, Roth, M P, Coppin, H

    Published in Gut (01-11-2002)
    “…Background: Although much progress has been made recently in characterising the proteins involved in duodenal iron trafficking, regulation of intestinal iron…”
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    The relationship between iron overload, clinical symptoms, and age in 410 patients with genetic hemochromatosis by Adams, P. C., Deugnier, Y., Moirand, R., Brissot, P.

    Published in Hepatology (Baltimore, Md.) (01-01-1997)
    “…The aim of this study was to investigate the relationship between iron overload, age, and clinical symptoms in genetic hemochromatosis. The relationship was…”
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    Antiproliferative and apoptotic effects in rat and human hepatoma cell cultures of the orally active iron chelator ICL670 compared to CP20: a possible relationship with polyamine metabolism by Lescoat, G., Chantrel-Groussard, K., Pasdeloup, N., Nick, H., Brissot, P., Gaboriau, F.

    Published in Cell proliferation (01-10-2007)
    “…  Objective: Iron loading has been observed to have a hyperproliferative effect on hepatocytes in vitro and on tumour cells in vivo; removal of this iron…”
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    Phenotypic expression of HFE mutations: A French study of 1110 unrelated iron-overloaded patients and relatives by Moirand, Romain, Jouanolle, Anne-Marie, Brissot, Pierre, Le Gall, Jean-Yves, David, Véronique, Deugnier, Yves

    Published in Gastroenterology (New York, N.Y. 1943) (01-02-1999)
    “…Background & Aims: Two mutations have been described in the HFE gene: C282Y and H63D. The aim of this study was to determine the phenotype of the different HFE…”
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    A genotypic study of 217 unrelated probands diagnosed as “genetic hemochromatosis” on “classical” phenotypic criteria by Brissot, Pierre, Moirand, Romain, Jouanolle, Anne-Marie, Guyader, Dominique, Gall, Jean-Yves Le, Deugnier, Yves, David, Véronique

    Published in Journal of hepatology (01-04-1999)
    “…Background/Aims: The HFE gene is a crucial candidate gene for hemochromatosis. The aims of this study were to assess the HFE genotypic profile in a large…”
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    Effects of phlebotomy therapy on cytochrome P450 2e1 activity and oxidative stress markers in dysmetabolic iron overload syndrome: a randomized trial by LAINÉ, F., REYMANN, J. M., MOREL, F., LANGOUËT, S., PERRIN, M., GUILLYGOMARC'H, A., BRISSOT, P., TURMEL, V., MOUCHEL, C., PAPE, D., BELLISSANT, E., DEUGNIER, Y.

    Published in Alimentary pharmacology & therapeutics (15-10-2006)
    “…Summary Aim To assess the effects of iron removal on cytochrome P450 2E1 activity and oxidative stress in dysmetabolic iron overload syndrome. Methods…”
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    Hemochromatosis: diagnosis and quantification of liver iron with gradient-echo MR imaging by Gandon, Y, Guyader, D, Heautot, J F, Reda, M I, Yaouanq, J, Buhé, T, Brissot, P, Carsin, M, Deugnier, Y

    Published in Radiology (01-11-1994)
    “…To assess the role of magnetic resonance (MR) imaging in detection and quantification of liver iron overload. MR imaging at 0.5 T was prospectively performed…”
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