Search Results - "BRIOT, Delphine"
-
1
Spontaneous abrogation of the G2 DNA damage checkpoint has clinical benefits but promotes leukemogenesis in Fanconi anemia patients
Published in The Journal of clinical investigation (04-01-2011)“…DNA damage checkpoints in the cell cycle may be important barriers against cancer progression in human cells. Fanconi anemia (FA) is an inherited DNA…”
Get full text
Journal Article -
2
scAAV9 intracisternal delivery results in efficient gene transfer to the central nervous system of a feline model of motor neuron disease
Published in Human gene therapy (01-07-2013)“…On the basis of previous studies suggesting that vascular endothelial growth factor (VEGF) could protect motor neurons from degeneration, adeno-associated…”
Get more information
Journal Article -
3
Fanconi anemia C gene product regulates expression of genes involved in differentiation and inflammation
Published in Oncogene (24-06-2004)“…Loss of Fanconi anemia (FA) proteins activity by recessive inherited mutations in one of the FA genes leads to a disease characterized by bone marrow failure,…”
Get full text
Journal Article -
4
ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia
Published in Blood (11-12-2014)“…T-cell acute lymphoblastic leukemia (T-ALL) is a high-risk subtype of acute lymphoblastic leukemia (ALL) with gradually improved survival through introduction…”
Get full text
Journal Article -
5
Aberrant activation of stress-response pathways leads to TNF-α oversecretion in Fanconi anemia
Published in Blood (15-02-2008)“…Fanconi anemia (FA), an inherited syndrome that associates bone marrow failure, cancer predisposition, and genetic instability, is characterized by an…”
Get full text
Journal Article -
6
Deletion 6q Drives T-cell Leukemia Progression by Ribosome Modulation
Published in Cancer discovery (01-12-2018)“…Deletion of chromosome 6q is a well-recognized abnormality found in poor-prognosis T-cell acute lymphoblastic leukemia (T-ALL). Using integrated genomic…”
Get more information
Journal Article -
7
Recombinant adeno-associated virus serotype 4 mediates unique and exclusive long-term transduction of retinal pigmented epithelium in rat, dog, and nonhuman primate after subretinal delivery
Published in Molecular therapy (01-06-2003)“…We previously described chimeric recombinant adeno-associated virus (rAAV) vectors 2/4 and 2/5 as the most efficient vectors in rat retina. We now characterize…”
Get full text
Journal Article -
8
Spontaneous abrogation of the [G.sub.2] DNA damage checkpoint has clinical benefits but promotes leukemogenesis in Fanconi anemia patients
Published in The Journal of clinical investigation (01-01-2011)“…DNA damage checkpoints in the cell cycle may be important barriers against cancer progression in human cells. Fanconi anemia (FA) is an inherited DNA…”
Get full text
Journal Article -
9
Spontaneous abrogation of the G^sub 2^ DNA damage checkpoint has clinical benefits but promotes leukemogenesis in Fanconi anemia patients
Published in The Journal of clinical investigation (01-01-2011)“…DNA damage checkpoints in the cell cycle may be important barriers against cancer progression in human cells. Fanconi anemia (FA) is an inherited DNA…”
Get full text
Journal Article -
10
Aberrant activation of stress-response pathways leads to TNF-α oversecretion in Fanconi anemia. Commentary
Published in Blood (2008)Get full text
Journal Article -
11
The Fanconi anemia pathway and the DNA interstrand cross-links repair
Published in Biochimie (01-11-2003)“…Fanconi anemia (FA) is a genetic cancer-predisposition syndrome characterized by bone marrow failure and cellular and chromosomal hypersensitivity to DNA…”
Get full text
Journal Article -
12
Sustained tetracycline-regulated transgene expression in vivo in rat retinal ganglion cells using a single type 2 adeno-associated viral vector
Published in The journal of gene medicine (01-06-2003)“…Background Viral vector delivery of neurotrophic‐expressing transgenes in the retina may retard or prevent the onset of blindness associated with photoreceptor…”
Get full text
Journal Article -
13
Spontaneous abrogation of the G₂DNA damage checkpoint has clinical benefits but promotes leukemogenesis in Fanconi anemia patients
Published in The Journal of clinical investigation (01-01-2011)“…DNA damage checkpoints in the cell cycle may be important barriers against cancer progression in human cells. Fanconi anemia (FA) is an inherited DNA…”
Get full text
Journal Article -
14
Neonatal systemic delivery of scAAV9 in rodents and large animals results in gene transfer to RPE cells in the retina
Published in Experimental eye research (01-10-2011)“…Systemic delivery of recombinant adeno-associated virus (rAAV) vectors has recently been shown to cross the blood brain barrier in rodents and large animals…”
Get full text
Journal Article