Search Results - "BRIMNES, JENS"

House Dust Mite-Specific Sublingual Immunotherapy Prevents the Development of Allergic Inflammation in a Mouse Model of Experimental Asthma by Hagner, Stefanie, Rask, Carola, Brimnes, Jens, Andersen, Peter Sejer, Raifer, Hartmann, Renz, Harald, Garn, Holger

“…Evidence regarding sublingual immunotherapy (SLIT) efficacy and its good safety profile has been demonstrated with pollen and house dust mite (HDM) allergens…”
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The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells by Nakazawa, Atsushi, Dotan, Iris, Brimnes, Jens, Allez, Matthieu, Shao, Ling, Tsushima, Fumihiko, Azuma, Miyuki, Mayer, Lloyd

“…Background & Aims: Previous studies have suggested that intestinal epithelial cells (IECs) may function as antigen-presenting cells for CD4 + and CD8 + T…”
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Sublingual immunotherapy in sensitized mice by Kildsgaard, Jens, PhD, Brimnes, Jens, PhD, Jacobi, Henrik, MD, Lund, Kaare, PhD

“…Background Many studies have demonstrated immunologic changes induced by sublingual immunotherapy (SLIT), but the definitive mechanism of action needs further…”
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Modulation of immune responses using adjuvants to facilitate therapeutic vaccination by Schijns, Virgil, Fernández‐Tejada, Alberto, Barjaktarović, Žarko, Bouzalas, Ilias, Brimnes, Jens, Chernysh, Sergey, Gizurarson, Sveinbjorn, Gursel, Ihsan, Jakopin, Žiga, Lawrenz, Maria, Nativi, Cristina, Paul, Stephane, Pedersen, Gabriel Kristian, Rosano, Camillo, Ruiz‐de‐Angulo, Ane, Slütter, Bram, Thakur, Aneesh, Christensen, Dennis, Lavelle, Ed C.

“…Therapeutic vaccination offers great promise as an intervention for a diversity of infectious and non‐infectious conditions. Given that most chronic health…”
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Sublingual allergen immunotherapy prevents house dust mite inhalant type 2 immunity through dendritic cell-mediated induction of Foxp3+ regulatory T cells by Van der Borght, Katrien, Brimnes, Jens, Haspeslagh, Eline, Brand, Stephanie, Neyt, Katrijn, Gupta, Shashank, Knudsen, Niels Peter Hell, Hammad, Hamida, Andersen, Peter S., Lambrecht, Bart N.

“…Sublingual allergen immunotherapy (SLIT) is an emerging treatment option for allergic asthma and a potential disease-modifying strategy for asthma prevention…”
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Enhanced efficacy of sublingual immunotherapy by liposome-mediated delivery of allergen by Aliu, Have, Rask, Carola, Brimnes, Jens, Andresen, Thomas Lars

“…Immunotherapy by sublingual administration of allergens provides high patient compliance and has emerged as an alternative to subcutaneous immunotherapy for…”
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Genetically engineered cell factories produce glycoengineered vaccines that target antigen-presenting cells and reduce antigen-specific T-cell reactivity by Mathiesen, Caroline B.K., Carlsson, Michael C., Brand, Stephanie, Möller, Svenning Rune, Idorn, Manja, thor Straten, Per, Pedersen, Anders E., Dabelsteen, Sally, Halim, Adnan, Würtzen, Peter Adler, Brimnes, Jens, Ipsen, Henrik, Petersen, Bent L., Wandall, Hans H.

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Defects in CD8+ Regulatory T Cells in the Lamina Propria of Patients with Inflammatory Bowel Disease by Brimnes, Jens, Allez, Matthieu, Dotan, Iris, Shao, Ling, Nakazawa, Atsushi, Mayer, Lloyd

“…Mucosal tolerance is believed to be partly mediated by regulatory T cells. Intestinal epithelial cells (IECs) may play an important role in the generation of…”
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Comparison of heparin-binding to lactoferrin from human milk and from human granulocytes by means of affinity capillary electrophoresis by Heegaard, N H, Brimnes, J

“…Human lactoferrin from two different sources: milk and secondary granules of neutrophil granulocytes, was compared with respect to heparin binding by means of…”
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Intestinal epithelial cells from inflammatory bowel disease patients preferentially stimulate CD4+ T cells to proliferate and secrete interferon-gamma by Dotan, Iris, Allez, Matthieu, Nakazawa, Atsushi, Brimnes, Jens, Schulder-Katz, Micoll, Mayer, Lloyd

“…Previous studies have suggested that intestinal epithelial cells (IECs) have the capacity to function as nonprofessional antigen presenting cells that in the…”
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Expansion of CD8+ T cells with regulatory function after interaction with intestinal epithelial cells by Allez, Matthieu, Brimnes, Jens, Dotan, Iris, Mayer, Lloyd

“…Background & Aims: Regulatory T cells play a role in the control of immune responses in the intestinal mucosa and their absence may predispose to inflammatory…”
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Glycoproteomic Analysis of Seven Major Allergenic Proteins Reveals Novel Post-translational Modifications by Halim, Adnan, Carlsson, Michael C., Madsen, Caroline Benedicte, Brand, Stephanie, Møller, Svenning Rune, Olsen, Carl Erik, Vakhrushev, Sergey Y., Brimnes, Jens, Wurtzen, Peter Adler, Ipsen, Henrik, Petersen, Bent L., Wandall, Hans H.

“…Allergenic proteins such as grass pollen and house dust mite (HDM) proteins are known to trigger hypersensitivity reactions of the immune system, leading to…”
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Induction of mucosal tolerance in Peyer's patch-deficient, ligated small bowel loops by Kraus, Thomas A, Brimnes, Jens, Muong, Christine, Liu, Jian-Hua, Moran, Thomas M, Tappenden, Kelly A, Boros, Peter, Mayer, Lloyd

“…To explore the requirement for M cells and the Peyer's patch (PP) in induction of oral tolerance and address the potential in vivo role of intestinal…”
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Activation of a Unique Population of CD8+ T Cells by Intestinal Epithelial Cells by ALLEZ, MATTHIEU, BRIMNES, JENS, SHAO, LING, DOTAN, IRIS, NAKAZAWA, ATSUSHI, MAYER, LLOYD

“…: Intestinal epithelial cells may play a role in the regulation of immune responses toward luminal antigens. We show that a subset of CD8+ T cells undergoes…”
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Enteric bacterial antigens activate CD4+ T cells from scid mice with inflammatory bowel disease by Brimnes, Jens, Reimann, Jörg, Nissen, Mogens H., Claesson, Mogens H.

“…Scid mice transplanted with CD4+ T cells from congenic donor mice develop a chronic and lethal inflammatory bowel disease (IBD) 2–3 months…”
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Defects in CD8 super(+) Regulatory T Cells in the Lamina Propria of Patients with Inflammatory Bowel Disease by Brimnes, Jens, Allez, Matthieu, Dotan, Iris, Shao, Ling, Nakazawa, Atsushi, Mayer, Lloyd

“…Mucosal tolerance is believed to be partly mediated by regulatory T cells. Intestinal epithelial cells (IECs) may play an important role in the generation of…”
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Induction of high and low dose oral tolerance in isolated small bowel loops with and without peyers patches by Brimnes, Jens, Kraus, Thomas, Shao, Ling, Boros, Peter, Mayer, Lloyd

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CD8+regulatory cells are present in normal lamina propria but are lacking in patients with inflammatory bowel disease by Brimnes, Jens, Allez, Matthieu, Dotan, Iris, Nakazawa, Atsushi, Mayer, Lloyd

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IL-10 is necessary for the induction of low dose tolerance by Brimnes, Jens, Shao, Ling, Kraus, Thomas, Mayer, Lloyd

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Enhanced Oral Tolerance in Transgenic Mice with Hepatocyte Secretion of IL-10 by Safadi, Rifaat, Alvarez, Carlos E, Ohta, Masayuki, Brimnes, Jens, Kraus, Thomas, Mehal, Wajahat, Bromberg, Jonathan, Mayer, Lloyd, Friedman, Scott L

“…Several cytokines derived from Th3 and Tr1 cells, including IL-10, are believed to regulate oral tolerance, but direct evidence is lacking. We have explored…”
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