Search Results - "BRIAN, William R"
-
1
Oxidation of dihydropyridine calcium channel blockers and analogs by human liver cytochrome P-450 IIIA4
Published in Journal of medicinal chemistry (01-06-1991)“…A series of 21 different 4-substituted 2,6-dimethyl-3-(alkoxycarbonyl)-1,4-dihydropyridines was considered with regard to oxidation to pyridine derivatives by…”
Get full text
Journal Article -
2
Non-well-founded extensions of documentclass{article}usepackage{amssymb}begin{document}pagestyle{empty}$mathbf {V}$end{document}
Published in Mathematical logic quarterly (01-05-2013)“…This paper describes a new and user‐friendly method for constructing models of non‐well‐founded set theory. Given a sufficiently well‐behaved system θ of…”
Get full text
Journal Article -
3
Catalytic activities of human liver cytochrome P-450 IIIA4 expressed in Saccharomyces cerevisiae
Published in Biochemistry (Easton) (01-12-1990)“…A human liver cytochrome P-450 (P-450) IIIA4 cDNA clone was inserted behind an alcohol dehydrogenase promoter in the plasmid vector pAAH5 and expressed in…”
Get full text
Journal Article -
4
The specification property and infinite entropy for certain classes of linear operators
Published in Journal of mathematical analysis and applications (15-09-2017)“…We study the specification property and infinite topological entropy for two specific types of linear operators: translation operators on weighted Lebesgue…”
Get full text
Journal Article -
5
Preservation and destruction in simple refinements
Published in Topology and its applications (01-12-2014)“…If σ is a topology on X and A⊆X, we let 〈σ,A〉 denote the topology generated by σ and A, i.e., the topology with σ∪{A} as a subbasis. Any refinement of a…”
Get full text
Journal Article -
6
Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae
Published in Biochemistry (Easton) (13-06-1989)“…The human liver cytochrome P-450 (P-450) proteins responsible for catalyzing the oxidation of mephenytoin, tolbutamide, and hexobarbital are encoded by a…”
Get full text
Journal Article -
7
Partitions of 2ω and completely ultrametrizable spaces
Published in Topology and its applications (01-04-2015)“…We prove that, for every n, the topological space ωnω (where ωn has the discrete topology) can be partitioned into ℵn copies of the Baire space. Using this…”
Get full text
Journal Article -
8
In-vivo phenotyping for CYP3A by a single-point determination of midazolam plasma concentration
Published in Pharmacogenetics (London) (01-12-2001)“…We investigated whether a single plasma midazolam concentration could serve as an accurate predictor of total midazolam clearance, an established in-vivo probe…”
Get full text
Journal Article -
9
Topics in general and set-theoretic topology: slice sets, rigid subsets of the reals, toronto spaces, cleavability, and 'neight'
Published 01-01-2013“…I explore five topics in topology using set-theoretic techniques. The first of these is a generalization of 2-point sets called slice sets. I show that, for…”
Get full text
Dissertation -
10
Topics in general and set-theoretic topology : slice sets, rigid subsets of the reals, Toronto spaces, cleavability, and 'neight'
Published 01-01-2013“…I explore five topics in topology using set-theoretic techniques. The first of these is a generalization of 2-point sets called slice sets. I show that, for…”
Get full text
Dissertation -
11
Quotients of $\mathbb{N}^$, $\omega$-limit sets, and chain transitivity
Published 31-12-2014“…$\mathbb{N}^* = \beta\mathbb{N} \setminus \mathbb{N}$ has a canonical dynamical structure provided by the shift map, the unique continuous extension to…”
Get full text
Journal Article -
12
P-sets and minimal right ideals in N
Published 22-10-2014“…Recall that a $P$-set is a closed set $X$ such that the intersection of countably many neighborhoods of $X$ is again a neighborhood of $X$. We show that if…”
Get full text
Journal Article -
13
Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3)
Published in Molecular pharmacology (01-08-1990)“…The human P450III family has been shown to be composed of at least four members, P450IIIA3 (HLp), P450IIIA4 (P450NF), P450IIIA5 (HLp3), and P450IIIA6 (HLp2)…”
Get more information
Journal Article -
14
Partitions of 2^{\omega} and completely ultrametrizable spaces
Published 05-06-2014“…We prove that, for every n, the topological space {\omega}_n^{\omega} (where {\omega}_n has the discrete topology) can be partitioned into {\omega}_n copies of…”
Get full text
Journal Article -
15
Effect of aging on mixed-function oxidation and conjugation by isolated perfused rat livers
Published in Biochemical pharmacology (01-07-1997)“…Aging is known to decrease hepatic cytochrome P450 content in rats. However, limited information is available on the effects of aging on mixed-function…”
Get full text
Journal Article -
16
Bicyclic N-Hydroxyurea Inhibitors of 5-Lipoxygenase: Pharmacodynamic, Pharmacokinetic, and in Vitro Metabolic Studies Characterizing N-Hydroxy-N-(2,3-dihydro-6-(phenylmethoxy)-3-benzofuranyl)urea
Published in Journal of medicinal chemistry (20-12-1996)“…A series of N-hydroxyurea derivatives have been prepared and examined as inhibitors of 5-lipoxygenase. Oral activity was established by examining the…”
Get full text
Journal Article -
17
Expression of mammalian cytochrome P450 enzymes using yeast-based vectors
Published in Methods in enzymology (1991)Get more information
Journal Article -
18
Diagnostic and therapeutic endoscopic approaches to intraductal papillary mucinous neoplasm
Published in World journal of gastrointestinal surgery (27-10-2010)“…Pancreatic cystic lesions are increasingly identified on routine imaging.One specific lesion,known as intraductal papillary mucinous neoplasm(IPMN),is a…”
Get full text
Journal Article -
19
The role of metabolism in chemical-induced pulmonary toxicity
Published in Toxicologic pathology (01-01-1991)“…The lung is a target organ for the toxic effects of several chemical agents, including natural products, industrial chemicals, pesticides, environmental…”
Get more information
Journal Article -
20
Human liver mephenytoin 4'-hydroxylase cytochrome P-450 proteins and genes
Published in Drug metabolism reviews (1989)Get more information
Journal Article