Search Results - "BRETTLER, D"

Characterization of the anti‐factor VIII immunoglobulin profile in patients with hemophilia A by use of a fluorescence‐based immunoassay by Boylan, B., Rice, A. S., Dunn, A. L., Tarantino, M. D., Brettler, D. B., Barrett, J. C., Miller, C. H., Abshire, T. C., Kempton, C. L., Bockenstedt, P. L., Di Paola, J. A., Radhi, M., Lentz, S. R., Massey, G., Neff, A. T., Shapiro, A. D., Wicklund, B. M., Manco‐Johnson, M. J., Knoll, C., Escobar, M. A., Elaine Eyster, M., Gill, J. C., Leissinger, C., Yaish, H.

“…Summary Background The development of neutralizing antibodies, referred to as inhibitors, against factor VIII is a major complication associated with FVIII…”
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Gene therapy for hemophilia? by BRETTLER, D. B.

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Home-based factor infusion therapy and hospitalization for bleeding complications among males with haemophilia by Soucie, J. M., Symons, J., Evatt, B., Brettler, D., Huszti, H., Linden, J.

“…Information from the medical records of 2650 US males with haemophilia living in six states was used to examine the influence of infusing factor concentrate at…”
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Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection by Kirchhoff, F, Greenough, T C, Brettler, D B, Sullivan, J L, Desrosiers, R C

“…All positive PCR amplifications (33 of 33) from these four patients yielded a full-length fragment corresponding to the wild-type strain by gel analysis, and…”
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Human Immunodeficiency Virus Type 1-Specific Cytotoxic T Lymphocytes (CTL), Virus Load, and CD4 T Cell Loss: Evidence Supporting a Protective Role for CTL In Vivo by Greenough, Thomas C., Brettler, Doreen B., Somasundaran, Mohan, Panicali, Dennis L., Sullivan, John L.

“…The relationships between primary human immunodeficiency virus type 1 (HIV-1) Gag-specific cytotoxic T lymphocyte (CTL) frequency, virus load, and CD4 T cell…”
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Modern treatment of haemophilia by BERNTORP, E, BOULYJENKOV, V, SEREMETIS, S, BRETTLER, D, CHANDY, M, JONES, P, LEE, C, LUSHER, J, MANNUCCI, P, PEAK, I, RICKARD, K

“…Many rapid advances have been made in the diagnosis and therapy of haemophilia. Nevertheless, the condition still poses problems and challenges (e.g., joint…”
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The Low Risk of Hepatitis C Virus Transmission Among Sexual Partners of Hepatitis C-Infected Hemophilic Males: An International, Multicenter Study by Brettler, D.B., Mannucci, P.M., Gringeri, A., Rasko, J.E., Forsberg, A.D., Rumi, M.G., Garsia, R.J., Rickard, K.A., Colombo, M.

“…To study the transmission rate of hepatitis C virus (HCV) in the female sexual partners of antibody-positive hemophilic males, 106 partners from three…”
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Long-Term Nonprogressive Infection with Human Immunodeficiency Virus Type 1 in a Hemophilia Cohort by Greenough, Thomas C., Brettler, Doreen B., Kirchhoff, Frank, Alexander, Louis, Alexander, Ronald C., O'Brien, Stephen J., Somasundaran, Mohan, Luzuriaga, Katherine, Sullivan, John L.

“…Seven long-term nonprogressors (LTNPs) have been identified in a cohort of 128 human immunodeficiency virus (HIV)-1 infected individuals with hemophilia…”
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Prevalence of Hepatitis C Virus Antibody in a Cohort of Hemophilia Patients by Brettler, D.B., Alter, H.J., Dienstag, J.L., Forsberg, A.D., Levine, P.H.

“…One hundred thirty-one patients followed at the New England Hemophilia Center (Worcester, MA) were tested for antibody to hepatitis C virus (HCV). All but two…”
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Human immunodeficiency virus in semen arises from a genetically distinct virus reservoir by Kiessling, A A, Fitzgerald, L M, Zhang, D, Chhay, H, Brettler, D, Eyre, R C, Steinberg, J, McGowan, K, Byrn, R A

“…The reservoir of human immunodeficiency virus (HIV) in semen is unknown. Several lines of evidence suggest that semen HIV may not arise from the same reservoir…”
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Menisectomy used to describe removal of meniscal tissue from the knee by Brettler, D

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Normal immune function and inability to isolate virus in culture in an individual with long-term human immunodeficiency virus type 1 infection by Greenough, T C, Somasundaran, M, Brettler, D B, Hesselton, R M, Alimenti, A, Kirchhoff, F, Panicali, D, Sullivan, J L

“…A detailed, longitudinal study was undertaken to investigate the immunological and virological features of an individual with hemophilia infected with human…”
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A 3.5-year study of immune function in persons with hemophilia infusing recombinant factor VIII by Brettler, D

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Deficient human immunodeficiency virus type 1-specific cytotoxic T cell responses in vertically infected children by Luzuriaga, K, Koup, R A, Pikora, C A, Brettler, D B, Sullivan, J L

“…Cytotoxic T lymphocyte (CTL) responses to human immunodeficiency virus type 1 (HIV-1) gag proteins were studied prospectively in 17 children (12 infected) born…”
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Anaphylaxis after treatment with recombinant factor VIII by Shopnick, R I, Kazemi, M, Brettler, D B, Buckwalter, C, Yang, L, Bray, G, Gomperts, E D

“…Treatment of hemophilia patients with recombinant factor VIII concentrates has not previously been associated with anaphylaxis. A 5-week-old boy with severe…”
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Factor Concentrates for Treatment of Hemophilia: Which One to Choose? by Brettler, Doreen B., Levine, Peter H.

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Limiting dilution analysis of cytotoxic T lymphocytes to human immunodeficiency virus gag antigens in infected persons : in vitro quantitation of effector cell populations with p17 and p24 specificities by KOUP, R. A, PIKORA, C. A, LUZURIAGA, K, BRETTLER, D. B, DAY, E. S, MAZZARA, G. P, SULLIVAN, J. L

“…The presence of cytotoxic T lymphocytes (CTL) to the gag antigens of human immunodeficiency virus (HIV) has been described in infected populations. We found…”
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Aetiology of AIDS-antibodies to human T-cell leukaemia virus (type III) in haemophiliacs by Kitchen, L. W, Barin, F, Sullivan, J. L, McLane, M. F, Brettler, D. B, Levine, P. H, Essex, M

“…Human T-cell leukaemia virus type III (HTLV-III) is suspected of having a key role in the pathogenesis of acquired immune deficiency syndrome (AIDS)…”
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Factor IXa-factor VIIIa-cell surface complex does not contribute to the basal activation of the coagulation mechanism in vivo by BAUER, K. A, MANNUCCI, P. M, GRINGERI, A, TRADATI, F, BARZEGAR, S, KASS, B. L, TEN CATE, H, KESTIN, A. S, BRETTLER, D. B, ROSENBERG, R. D

“…We have infused recombinant factor VIIa into patients with hereditary factor VII deficiency with marked reductions in plasma concentrations of factor IX…”
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Three-year randomised study of high-purity or intermediate-purity factor VIII concentrates in symptom-free HIV-seropositive haemophiliacs: effects on immune status by Seremetis, S V, Aledort, L M, Bergman, G E, Bona, R, Bray, G, Brettler, D, Eyster, M E, Kessler, C, Lau, T S, Lusher, J

“…The availability of monoclonal-antibody-purified factor VIII (FVIII) concentrates allows us to test the hypothesis, based on in vitro observations, that their…”
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