Search Results - "BRESNICK, Edward"

Identification of Positive and Negative Regulatory Elements of the Human Cytochrome P4501A2 (CYP1A2) Gene by Chung, Injae, Bresnick, Edward

“…We previously demonstrated an enhancer-like positive regulatory element within a 259-bp sequence (−2352 to −2094 bp) of the humanCYP1A2gene in HepG2 cells…”
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Glycine N-Methyltransferase Is an Example of Functional Diversity by Bhat, Rashid, Bresnick, Edward

“…The cytochrome P-4501A1 (CYP1A1) gene is regulated by several trans-acting factors including the 4 S polycyclic aromatic hydrocarbon (PAH)-binding protein,…”
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ATP Depletion Affects the Phosphorylation State, Ligand Binding, and Nuclear Transport of the 4 S Polycyclic Aromatic Hydrocarbon-binding Protein in Rat Hepatoma Cells by Bhat, Rashid, Weaver, James A., Wagner, Conrad, Bodwell, Jack E., Bresnick, Edward

“…In the rat, cytochrome P4501A1 gene expression is thought to be regulated by several trans-acting factors including the 4 S polycyclic aromatic hydrocarbon…”
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Distinct roles for p53 transactivation and repression in preventing UCN-01-mediated abrogation of DNA damage-induced arrest at S and G2 cell cycle checkpoints by LEVESQUE, Aime A, KOHN, Ethan A, BRESNICK, Edward, EASTMAN, Alan

“…The topoisomerase I inhibitor SN38 arrests cell cycle progression primarily in S or G(2) phases of the cell cycle in a p53-independent manner. The Chk1…”
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Retirement or relearning the joys of the discovery process by Bresnick, Edward

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LETTER FROM THE EDITOR by Bresnick, Edward

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LETTER FROM THE EDITOR by Bresnick, Edward

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Positive and negative regulation of ΔN-p63 promoter activity by p53 and ΔN-p63-α contributes to differential regulation of p53 target genes by HARMES, David Christopher, BRESNICK, Edward, LUBIN, Emma A, WATSON, Julie K, HEIM, Kelly E, CURTIN, Joshua C, SUSKIND, Anne M, LAMB, Justin, DIRENZO, James

“…Mammary epithelial regeneration implies the existence of cellular progenitors with retained replicative capacity, prolonged lifespan and developmental potency…”
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Glycine N-methyltransferase is an example of functional diversity. Role as a polycyclic aromatic hydrocarbon-binding receptor by Bhat, R, Bresnick, E

“…The cytochrome P-4501A1 (CYP1A1) gene is regulated by several trans-acting factors including the 4 S polycyclic aromatic hydrocarbon (PAH)-binding protein,…”
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Phospholipase activity in skin after application of phorbol esters and 3-methylcholanthrene by Bresnick, E, Bailey, G, Bonney, R J, Wightman, P

“…Topical administration of the promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA), is accompanied by an increased incorporation of [3H]arachidonic acid into…”
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Inhibitory effect of apigenin, a plant flavonoid, on epidermal ornithine decarboxylase and skin tumor promotion in mice by Wei, H, Tye, L, Bresnick, E, Birt, D F

“…This investigation studied the effect of topical application of apigenin on skin tumorigenesis initiated by 7,12-dimethylbenz(a)anthracene (DMBA) and promoted…”
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Positive and negative regulation of [Delta]N-p63 promoter activity by p53 and [Delta]N-p63-[alpha] contributes to differential regulation of p53 target genes by Harmes, David Christopher, Bresnick, Edward, Lubin, Emma A, Watson, Julie K, Heim, Kelly E, Curtin, Joshua C, Suskind, Anne M, Lamb, Justin, DiRenzo, James

“…Mammary epithelial regeneration implies the existence of cellular progenitors with retained replicative capacity, prolonged lifespan and developmental potency…”
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Positive and negative regulation of deltaN-p63 promoter activity by p53 and deltaN-p63-alpha contributes to differential regulation of p53 target genes by Harmes, David Christopher, Bresnick, Edward, Lubin, Emma A, Watson, Julie K, Heim, Kelly E, Curtin, Joshua C, Suskind, Anne M, Lamb, Justin, DiRenzo, James

“…Mammary epithelial regeneration implies the existence of cellular progenitors with retained replicative capacity, prolonged lifespan and developmental potency…”
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Oct-1 transcription factor is a negative regulator of rat CYP1A1 expression via an octamer sequence in its negative regulatory element by Sterling, K, Bresnick, E

“…The rat CYP1A1 negative regulatory element (NRE) contains AP-1 and Oct-1 motifs at -808 to -788 bp. The CYP1A1 sequence from -813 to -779 bp and an identical…”
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The Homodimeric Form of Glycine N-Methyltransferase Acts as a Polycyclic Aromatic Hydrocarbon-Binding Receptor by Bhat, Rashid, Wagner, Conrad, Bresnick, Edward

“…In the rat, cytochrome P4501A1 gene expression is thought to be regulated by several trans-acting factors including the 4S polycyclic aromatic hydrocarbon…”
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Regulation of the constitutive expression of the human CYP1A2 gene: cis elements and their interactions with proteins by Chung, I, Bresnick, E

“…Cytochrome P4501A2 (CYP1A2) is a member of the cytochrome P450 family that is involved in phase I drug metabolism in vertebrates. To understand how the…”
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Retrovirus-mediated transfer of the human O 6-Methylguanine-DNA methyltransferase gene into a murine hematopoietic stem cell line and resistance to the toxic effects of certain alkylating agents by Gang, Wang, Weiss, Clifford, Sheng, Peihua, Bresnick, Edward

“…O 6-Methylguanine-DNA methyltransferase (MGMT) is an important DNA repair protein that plays a key role in cancer chemotherapy by alkylating agents such as…”
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3-Methylcholanthrene-mediated induction of cytochrome P4501A2 in human hepatoma HepG2 cells as quantified by the reverse transcription-polymerase chain reaction by Chung, I, Bresnick, E

“…The feasibility of using HepG2 human hepatoma cells to study the regulation of the expression of the cytochrome P4501A2 gene (CYP1A2) was examined. The reverse…”
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Glycine N-Methyltransferase Is a Mediator of Cytochrome P4501A1 Gene Expression by Raha, A., Joyce, T., Gusky, S., Bresnick, E.

“…Cytochrome P4501A1, the isozyme most closely approximating aryl hydrocarbon hydroxylase activity under conditions of induction, is thought to be regulated by…”
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Nuclear transcription factor Oct-1 binds to the 5′-upstream region of CYP1 A1 and negatively regulates its expression by Brat, Rashid, Weaver, James A., Sterling, Kenneth M., Bresnick, Edward

“…The cytochrome P450-dependent monooxygenases, which represent an extended superfamily, catalyze the biotransformation of many endogenous and exogenous…”
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