Search Results - "BRENTNALL, T. A"

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  1. 1

    Ursodiol use is associated with lower prevalence of colonic neoplasia in patients with ulcerative colitis and primary sclerosing cholangitis by TUNG, Bruce Y, EMOND, Mary J, HAGGITT, Rodger C, BRONNER, Mary P, KIMMEY, Michael B, KOWDLEY, Kris V, BRENTNALL, Teresa A

    Published in Annals of internal medicine (16-01-2001)
    “…Patients with ulcerative colitis and primary sclerosing cholangitis are at high risk for colonic dysplasia and cancer. This risk approaches 50% after 25 years…”
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    Journal Article
  2. 2

    Early diagnosis and treatment of pancreatic dysplasia in patients with a family history of pancreatic cancer by BRENTNALL, T. A, BRONNER, M. P, BYRD, D. R, HAGGITT, R. C, KIMMEY, M. B

    Published in Annals of internal medicine (17-08-1999)
    “…Pancreatic cancer, the fourth most common cause of cancer death in the United States, is hereditary in an estimated 10% of cases. Surveillance of patients with…”
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    Journal Article
  3. 3

    Risk and natural history of colonic neoplasia in patients with primary sclerosing cholangitis and ulcerative colitis by Brentnall, TA, Haggitt, RC, Rabinovitch, PS, Kimmey, MB, Bronner, MP, Levine, DS, Kowdley, KV, Stevens, AC, Crispin, DA, Emond, M, Rubin, CE

    Published in Gastroenterology (New York, N.Y. 1943) (01-02-1996)
    “…BACKGROUND & AIMS: Primary sclerosing cholangitis (PSC) has been suggested as a risk factor for the development of colorectal cancer in ulcerative colitis…”
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  4. 4

    Pancolonic chromosomal instability precedes dysplasia and cancer in ulcerative colitis by RABINOVITCH, P. S, DZIADON, S, BRENTNALL, T. A, EMOND, M. J, CRISPIN, D. A, HAGGITT, R. C, BRONNER, M. P

    Published in Cancer research (Chicago, Ill.) (15-10-1999)
    “…Patients with long-standing ulcerative colitis (UC) are at increased risk for colon cancer. These cancers are thought to arise from preexisting dysplasia in a…”
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  5. 5

    Mutations in the p53 gene: an early marker of neoplastic progression in ulcerative colitis by Brentnall, T A, Crispin, D A, Rabinovitch, P S, Haggitt, R C, Rubin, C E, Stevens, A C, Burmer, G C

    Published in Gastroenterology (New York, N.Y. 1943) (01-08-1994)
    “…In long-term extensive ulcerative colitis, aneuploidy occurs earlier and loss of heterozygosity for p53 (p53 LOH) later during histological progression towards…”
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  6. 6

    Inherited predisposition to pancreatic cancer by EFTHIMIOU, E, CRNOGORAC-JURCEVIC, T, LEMOINE, N R, BRENTNALL, T A

    Published in Gut (01-02-2001)
    “…Traditional chemotherapy and radiotherapy regimens have been rather ineffective in providing control of the disease. 1 The only consistent risk factor…”
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    Journal Article
  7. 7

    Microsatellite instability in nonneoplastic mucosa from patients with chronic ulcerative colitis by BRENTNALL, T. A, CRISPIN, D. A, BRONNER, M. P, CHERIAN, S. P, HUEFFED, M, RABINOVITCH, P. S, RUBIN, C. E, HAGGITT, R. C, BOLAND, C. R

    Published in Cancer research (Chicago, Ill.) (15-03-1996)
    “…Microsatellite instability (MIN) has been detected in many cancer types; however, recently we also observed it in the nonneoplastic but inflammatory setting of…”
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  8. 8

    Cancer surveillance of patients from familial pancreatic cancer kindreds by Brentnall, T A

    Published in The Medical clinics of North America (01-05-2000)
    “…The family history can be used to determine which family members warrant surveillance and when to start it. Surveillance should be started at least 1 decade…”
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  9. 9

    DNA aneuploidy in colonic biopsies predicts future development of dysplasia in ulcerative colitis by Rubin, C E, Haggitt, R C, Burmer, G C, Brentnall, T A, Stevens, A C, Levine, D S, Dean, P J, Kimmey, M, Perera, D R, Rabinovitch, P S

    Published in Gastroenterology (New York, N.Y. 1943) (01-11-1992)
    “…The objective of the present study was to determine whether abnormal epithelial DNA content (aneuploidy) in colonic biopsy specimens from ulcerative colitis…”
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  10. 10

    Microsatellite instability and K-ras mutations associated with pancreatic adenocarcinoma and pancreatitis by BRENTNALL, T. A, RU CHEN, LEE, J. G, KIMMEY, M. B, BRONNER, M. P, HAGGITT, R. C, KOWDLEY, K. V, HECKER, L. M, BYRD, D. R

    Published in Cancer research (Chicago, Ill.) (01-10-1995)
    “…ras oncogene mutations and microsatellite instability (MIN) have been described in pancreatic cancer studies from paraffin blocks and fresh frozen tissue. We…”
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  11. 11

    Neoplastic progression in ulcerative colitis: histology, DNA content, and loss of a p53 allele by Burmer, G C, Rabinovitch, P S, Haggitt, R C, Crispin, D A, Brentnall, T A, Kolli, V R, Stevens, A C, Rubin, C E

    Published in Gastroenterology (New York, N.Y. 1943) (01-11-1992)
    “…Neoplastic progression in patients with chronic ulcerative colitis (UC) is characterized by the development of epithelial dysplasia, which is accompanied by…”
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  12. 12
  13. 13

    Accelerated age-related CpG island methylation in ulcerative colitis by ISSA, Jean-Pierre J, AHUJA, Nita, TOYOTA, Minoru, BRONNER, Mary P, BRENTNALL, Teresa A

    Published in Cancer research (Baltimore) (01-05-2001)
    “…CpG island hypermethylation is a mechanism of gene silencing that can be usurped by neoplastic cells to inactivate undesirable genes. In the colon,…”
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    Conference Proceeding Journal Article
  14. 14

    Persistent nausea and anorexia after marrow transplantation : A prospective study of 78 patients by WU, D, HOCKENBERY, D. M, BRENTNALL, T. A, BAEHR, P. H, PONEC, R. J, KUVER, R, TZUNG, S.-P, TODARO, J. L, MCDONALD, G. B

    Published in Transplantation (27-11-1998)
    “…Persistent nausea, vomiting, anorexia, and poor oral intake are common after hematopoietic cell transplantation. In the past, herpesvirus infections and acute…”
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  15. 15

    A germline substitution in the human MSH2 gene is associated with high-grade dysplasia and cancer in ulcerative colitis by Brentnall, T A, Rubin, C E, Crispin, D A, Stevens, A, Batchelor, R H, Haggitt, R C, Bronner, M P, Evans, J P, McCahill, L E, Bilir, N

    Published in Gastroenterology (New York, N.Y. 1943) (01-07-1995)
    “…The DNA mismatch repair gene human MSH2 shows a germline mutation in certain family members with hereditary nonpolyposis colorectal cancer. There is an…”
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  16. 16

    Chromosomal instability in ulcerative colitis is related to telomere shortening by Rabinovitch, Peter S, O'Sullivan, Jacintha N, Bronner, Mary P, Brentnall, Teresa A, Finley, Jennifer C, Shen, Wen-Tang, Emerson, Scott, Emond, Mary J, Gollahon, Katherine A, Moskovitz, Alexander H, Crispin, David A, Potter, John D

    Published in Nature genetics (01-10-2002)
    “…Ulcerative colitis, a chronic inflammatory disease of the colon, is associated with a high risk of colorectal carcinoma that is thought to develop through…”
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  17. 17

    Familial pancreatic adenocarcinoma: association with diabetes and early molecular diagnosis by Evans, J P, Burke, W, Chen, R, Bennett, R L, Schmidt, R A, Dellinger, E P, Kimmey, M, Crispin, D, Brentnall, T A, Byrd, D R

    Published in Journal of medical genetics (01-05-1995)
    “…We report a large pedigree in which pancreatic cancer is inherited in an autosomal dominant fashion. Diabetes and exocrine insufficiency was observed in all…”
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    Journal Article
  18. 18

    The Role of Cyclooxygenase 2 in Ulcerative Colitis-Associated Neoplasia by Agoff, S. Nicholas, Brentnall, Teresa A., Crispin, David A., Taylor, Shari L., Raaka, Stuart, Haggitt, Rodger C., Reed, Michael W., Afonina, Irina A., Rabinovitch, Peter S., Stevens, Allyn C., Feng, Ziding, Bronner, Mary P.

    Published in The American journal of pathology (01-09-2000)
    “…Cyclooxygenase 2 (COX-2) overexpression has been described in sporadic colonic neoplasia, but its role in ulcerative colitis (UC) neoplastic progression…”
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  19. 19

    Characterization of the neoplastic phenotype in the familial atypical multiple‐mole melanoma–pancreatic carcinoma syndrome by Rulyak, Stephen J., Brentnall, Teresa A., Lynch, Henry T., Austin, Melissa A.

    Published in Cancer (15-08-2003)
    “…BACKGROUND Previous studies suggest that the familial atypical multiple‐mole melanoma (FAMMM) syndrome may predispose affected families to nonmelanoma…”
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  20. 20

    Inherited Pancreatic Cancer: Surveillance and Treatment Strategies for Affected Families by Rulyak, Stephen J., Brentnall, Teresa A.

    “…Background:Nearly 10% of pancreatic cancers are hereditary in origin, and in some individuals, the risk of pancreatic cancer approaches 50%. A number of…”
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