Search Results - "BREITNER, J"

Intranasal insulin improves cognition and modulates β-amyloid in early AD by REGER, M. A, WATSON, G. S, MEHTA, P, CRAFT, S, GREEN, P. S, WILKINSON, C. W, BAKER, L. D, CHOLERTON, B, FISHEL, M. A, PLYMATE, S. R, BREITNER, J. C. S, DEGROODT, W

“…Reduced brain insulin signaling and low CSF-to-plasma insulin ratios have been observed in patients with Alzheimer disease (AD). Furthermore,…”
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Occupational exposure to pesticides increases the risk of incident AD: The Cache County Study by HAYDEN, K. M, NORTON, M. C, DARCEY, D, OSTBYE, T, ZANDI, P. P, BREITNER, J. C. S, WELSH-BOHMER, K. A

“…Commonly used organophosphate and organochlorine pesticides inhibit acetylcholinesterase at synapses in the somatic, autonomic, and central nervous systems and…”
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Risk of dementia and AD with prior exposure to NSAIDs in an elderly community-based cohort by BREITNER, J. C. S, HANEUSE, S. J. P. A, WALKER, R, DUBLIN, S, CRANE, P. K, GRAY, S. L, LARSON, E. B

“…Nonsteroidal anti-inflammatory drugs (NSAIDs) may prevent Alzheimer dementia (AD). We analyzed the association of prior NSAID exposure with incident dementia…”
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Neuropsychiatric Symptoms as Risk Factors for Progression From CIND to Dementia: The Cache County Study by Peters, M.E., M.D, Rosenberg, P.B., M.D, Steinberg, M., M.D, Norton, M.C., Ph.D, Welsh-Bohmer, K.A., Ph.D, Hayden, K.M., Ph.D, Breitner, J., M.D., M.P.H, Tschanz, J.T., Ph.D, Lyketsos, C.G., M.D., M.H.S

“…Objectives To examine the association of neuropsychiatric symptom (NPS) severity with risk of transition to all-cause dementia, Alzheimer disease (AD), and…”
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Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease by LI, G, LARSON, E. B, SONNEN, J. A, SHOFER, J. B, PETRIE, E. C, SCHANTZ, A, PESKIND, E. R, RASKIND, M. A, BREITNER, J. C. S, MONTINE, T. J

“…Treatment with 3-hydroxy-3-methylglutaryl-coenzyme-A reductase inhibitors ("statins") has been associated in some epidemiologic studies with reduced risk of…”
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Correction: Midlife adiposity predicts earlier onset of Alzheimer’s dementia, neuropathology and presymptomatic cerebral amyloid accumulation by Chuang, Y-F, An, Y., Bilgel, M., Wong, D. F., Troncoso, J. C., O’Brien, R. J., Breitner, J. C., Ferrucci, L., Resnick, S. M., Thambisetty, M.

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Midlife adiposity predicts earlier onset of Alzheimer’s dementia, neuropathology and presymptomatic cerebral amyloid accumulation by Chuang, Y-F, An, Y, Bilgel, M, Wong, D F, Troncoso, J C, O'Brien, R J, Breitner, J C, Ferrucci, L, Resnick, S M, Thambisetty, M

“…Understanding how midlife risk factors influence age at onset (AAO) of Alzheimer’s disease (AD) may provide clues to delay disease expression. Although midlife…”
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The association of psychotropic medication use with the cognitive, functional, and neuropsychiatric trajectory of Alzheimer's disease by Rosenberg, P. B., Mielke, M. M., Han, D., Leoutsakos, J. S., Lyketsos, C. G., Rabins, P. V., Zandi, P. P., Breitner, J. C. S., Norton, M. C., Welsh-Bohmer, K. A., Zuckerman, I. H., Rattinger, G. B., Green, R. C., Corcoran, C., Tschanz, J. T.

“…Objective The use of psychotropic medications in Alzheimer's disease (AD) has been associated with both deleterious and potentially beneficial outcomes. We…”
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NSAID use and dementia risk in the Cardiovascular Health Study : Role of APOE and NSAID type by SZEKELY, C. A, BREITNER, J. C. S, FITZPATRICK, A. L, REA, T. D, PSATY, B. M, KULLER, L. H, ZANDI, P. P

“…Epidemiologic and laboratory studies suggest that nonsteroidal antiinflammatory drugs (NSAIDs) reduce risk of Alzheimer disease (AD). We therefore investigated…”
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Observations on DSM-5 Mild Neurocognitive Disorder vs. its predecessor, Mild Cognitive Impairment by Breitner, J. C. S.

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Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial by Lyketsos, C G, Breitner, J C S, Green, R C, Martin, B K, Meinert, C, Piantadosi, S, Sabbagh, M

“…To evaluate the efficacy and safety of naproxen and celecoxib for the primary prevention of Alzheimer disease (AD). Randomized, placebo-controlled,…”
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Conversion to dementia from mild cognitive disorder : The Cache County Study by TSCHANZ, J. T, WELSH-BOHMER, K. A, BREITNER, J. C. S, LYKETSOS, C. G, CORCORAN, C, GREEN, R. C, HAYDEN, K, NORTON, M. C, ZANDI, P. P, TOONE, L, WEST, N. A

“…To examine 3-year rates of conversion to dementia, and risk factors for such conversion, in a population-based sample with diverse types of cognitive…”
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Does NSAID use modify cognitive trajectories in the elderly? : The Cache County Study by HAYDEN, K. M, ZANDI, P. P, BREITNER, J. C. S, WELSH-BOHMER, K. A, KHACHATURIAN, A. S, SZEKELY, C. A, FOTUHI, M, NORTON, M. C, TSCHANZ, J. T, PIEPER, C. F, CORCORAN, C, LYKETSOS, C. G

“…Epidemiologic studies have suggested that nonsteroidal anti-inflammatory drugs (NSAIDs) may be useful for the prevention of Alzheimer disease (AD). By…”
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Vascular factors predict rate of progression in Alzheimer disease by Mielke, M M, Rosenberg, P B, Tschanz, J, Cook, L, Corcoran, C, Hayden, K M, Norton, M, Rabins, P V, Green, R C, Welsh-Bohmer, K A, Breitner, J C S, Munger, R, Lyketsos, C G

“…While there is considerable epidemiologic evidence that cardiovascular risk factors increase risk of incident Alzheimer disease (AD), few studies have examined…”
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Nonsteroidal anti-inflammatory drugs are associated with increased neuritic plaques by SONNEN, J. A, LARSON, E. B, WALKER, R. L, HANEUSE, S, CRANE, P. K, GRAY, S. L, BREITNER, J. C. S, MONTINE, T. J

“…Observational and experimental studies suggest that nonsteroidal anti-inflammatory drugs (NSAIDs) may protect against Alzheimer disease (AD); however, clinical…”
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Mental and Behavioral Disturbances in Dementia: Findings From the Cache County Study on Memory in Aging by Lyketsos, Constantine G., Steinberg, Martin, Tschanz, JoAnn T., Norton, Maria C., Steffens, David C., Breitner, John C.S.

“…OBJECTIVE: The authors report findings from a study of 5,092 community residents who constituted 90% of the elderly resident population of Cache County, Utah…”
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A hierarchy of predictors for dementia-free survival in old-age: results of the AgeCoDe study by Luck, T., Riedel-Heller, S. G., Luppa, M., Wiese, B., Bachmann, C., Jessen, F., Bickel, H., Weyerer, S., Pentzek, M., König, H.-H., Prokein, J., Eisele, M., Wagner, M., Mösch, E., Werle, J., Fuchs, A., Brettschneider, C., Scherer, M., Breitner, J. C. S., Maier, W.

“…Objective Progression from cognitive impairment (CI) to dementia is predicted by several factors, but their relative importance and interaction are unclear…”
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Risk factors for neuropsychiatric symptoms in dementia: the Cache County Study by Steinberg, M., Corcoran, C., Tschanz, J.T., Huber, C., Welsh-Bohmer, K., Norton, M.C., Zandi, P., Breitner, J.C.S., Steffens, D.C., Lyketsos, C.G.

“…Objective To investigate the probability of individual neuropsychiatric symptoms in dementia patients as a function of eight risk factors. Methods In the Cache…”
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Incidence of AD may decline in the early 90s for men, later for women: The Cache County Study by MIECH, R. A, BREITNER, J. C. S, ZANDI, P. P, KHACHATURIAN, A. S, ANTHONY, J. C, MAYER, L

“…To characterize the incidence of AD among the elderly population of Cache County, UT, noted for its longevity and high response rates; to explore sex…”
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Antioxidant intake and cognitive function of elderly men and women: the Cache County Study by Wengreen, H J, Munger, R G, Corcoran, C D, Zandi, P, Hayden, K M, Fotuhi, M, Skoog, I, Norton, M C, Tschanz, J, Breitner, J C S, Welsh-Bohmer, K A

“…We prospectively examined associations between intakes of antioxidants (vitamins C, vitamin E, and carotene) and cognitive function and decline among elderly…”
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