Search Results - "BREGNI, Marco"

Castration-Induced Downregulation of SPARC in Stromal Cells Drives Neuroendocrine Differentiation of Prostate Cancer by Enriquez, Claudia, Cancila, Valeria, Ferri, Renata, Sulsenti, Roberta, Fischetti, Irene, Milani, Matteo, Ostano, Paola, Gregnanin, Ilaria, Mello-Grand, Maurizia, Berrino, Enrico, Bregni, Marco, Renne, Giuseppe, Tripodo, Claudio, Colombo, Mario P, Jachetti, Elena

“…Fatal neuroendocrine differentiation (NED) of castration-resistant prostate cancer is a recurrent mechanism of resistance to androgen deprivation therapies…”
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SETBP1 induces transcription of a network of development genes by acting as an epigenetic hub by Piazza, Rocco, Magistroni, Vera, Redaelli, Sara, Mauri, Mario, Massimino, Luca, Sessa, Alessandro, Peronaci, Marco, Lalowski, Maciej, Soliymani, Rabah, Mezzatesta, Caterina, Pirola, Alessandra, Banfi, Federica, Rubio, Alicia, Rea, Delphine, Stagno, Fabio, Usala, Emilio, Martino, Bruno, Campiotti, Leonardo, Merli, Michele, Passamonti, Francesco, Onida, Francesco, Morotti, Alessandro, Pavesi, Francesca, Bregni, Marco, Broccoli, Vania, Baumann, Marc, Gambacorti-Passerini, Carlo

“…SETBP1 variants occur as somatic mutations in several hematological malignancies such as atypical chronic myeloid leukemia and as de novo germline mutations in…”
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Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I–II study by Ciceri, Fabio, MD, Bonini, Chiara, MD, Stanghellini, Maria Teresa Lupo, MD, Bondanza, Attilio, MD, Traversari, Catia, BSc, Salomoni, Monica, BSc, Turchetto, Lucia, PhD, Colombi, Scialini, BSc, Bernardi, Massimo, MD, Peccatori, Jacopo, MD, Pescarollo, Alessandra, MD, Servida, Paolo, MD, Magnani, Zulma, BSc, Perna, Serena K, MD, Valtolina, Veronica, MSc, Crippa, Fulvio, MD, Callegaro, Luciano, RN, Spoldi, Elena, PhD, Crocchiolo, Roberto, MD, Fleischhauer, Katharina, MD, Ponzoni, Maurilio, MD, Vago, Luca, MD, Rossini, Silvano, MD, Santoro, Armando, MD, Todisco, Elisabetta, MD, Apperley, Jane, Prof, Olavarria, Eduardo, MD, Slavin, Shimon, Prof, Weissinger, Eva M, MD, Ganser, Arnold, Prof, Stadler, Michael, MD, Yannaki, Evangelia, MD, Fassas, Athanasios, MD, Anagnostopoulos, Achilles, MD, Bregni, Marco, MD, Stampino, Corrado Gallo, MD, Bruzzi, Paolo, MD, Bordignon, Claudio, Prof

“…Summary Background Procedures to prevent severe graft-versus-host disease (GVHD) delay immune reconstitution secondary to transplants of haploidentical…”
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Antitumor effects of HSV-TK–engineered donor lymphocytes after allogeneic stem-cell transplantation by Ciceri, Fabio, Bonini, Chiara, Marktel, Sarah, Zappone, Elisabetta, Servida, Paolo, Bernardi, Massimo, Pescarollo, Alessandra, Bondanza, Attilio, Peccatori, Jacopo, Rossini, Silvano, Magnani, Zulma, Salomoni, Monica, Benati, Claudia, Ponzoni, Maurilio, Callegaro, Luciano, Corradini, Paolo, Bregni, Marco, Traversari, Catia, Bordignon, Claudio

“…The extensive exploitation of the antitumor effect of donor lymphocytes infused after allogeneic hematopoietic stem-cell transplantation (allo-HSCT) is limited…”
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High-Dose Chemotherapy With Autologous Hematopoietic Stem-Cell Transplantation in Metastatic Breast Cancer: Overview of Six Randomized Trials by BERRY, Donald A, UENO, Naoto T, CROWN, John P, SCHMID, Peter, LOTZ, Jean-Pierre, ROSTI, Giovanni, BREGNI, Marco, DEMIRER, Taner, JOHNSON, Marcella M, XIUDONG LEI, CAPUTO, Jean, SMITH, Dori A, YANCEY, Linda J, CRUMP, Michael, STADTMAUER, Edward A, BIRON, Pierre

“…High doses of effective chemotherapy are compelling if they can be delivered safely. Substantial interest in supporting high-dose chemotherapy with bone marrow…”
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High-Dose Chemotherapy With Autologous Stem-Cell Support As Adjuvant Therapy in Breast Cancer: Overview of 15 Randomized Trials by BERRY, Donald A, UENO, Naoto T, BERGH, Jonas, NITZ, Ulrike A, GIANNI, Alessandro M, BASSER, Russell L, ZANDER, Axel R, COOMBES, R. Charles, ROCHE, Henri, TOKUDA, Yutaka, DE VRIES, Elisabeth G. E, HORTOBAGYI, Gabriel N, JOHNSON, Marcella M, CROWN, John P, PEDRAZZOLI, Paolo, BREGNI, Marco, DEMIRER, Taner, XIUDONG LEI, CAPUTO, Jean, RODENHUIS, Sjoerd, PETERS, William P, LEONARD, Robert C, BARLOW, William E, TALLMAN, Martin S

“…Adjuvant high-dose chemotherapy (HDC) with autologous hematopoietic stem-cell transplantation (AHST) for high-risk primary breast cancer has not been shown to…”
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Graft-Versus-Lymphoma Effect in Relapsed Peripheral T-Cell Non-Hodgkin's Lymphomas After Reduced-Intensity Conditioning Followed by Allogeneic Transplantation of Hematopoietic Cells by CORRADINI, Paolo, DODERO, Anna, RAMBALDI, A, GIANNI, Alessandro M, TARELLA, Corrado, ZALLIO, Francesco, CARACCIOLO, Daniele, CASINI, Marco, BREGNI, Marco, NARNI, Franco, PATRIARCA, Francesca, BOCCADORO, Mario, BENEDETTI, Fabio

“…Peripheral T-cell lymphomas (PTCLs) are a heterogeneous group of malignancies characterized by a poor prognosis. We performed a pilot study to investigate the…”
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Transplantation of allogeneic hematopoietic stem cells: an emerging treatment modality for solid tumors by Bregni, Marco, Demirer, Taner, Barkholt, Lisbeth, Blaise, Didier, Pedrazzoli, Paolo, Aglietta, Massimo, Carella, Angelo Michele, Bay, Jacques-Olivier, Arpaci, Fikret, Rosti, Giovanni, Gurman, Gunhan, Niederwieser, Dietger

“…Allogeneic non-myeloablative stem-cell transplantation is feasible for patients with various refractory and advanced solid tumors. Current data suggest that…”
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Circulating biomarkers and cardiac function over 3 years after chemotherapy with anthracyclines: the ICOS‐ONE trial by Meessen, Jennifer M.T.A., Cardinale, Daniela, Ciceri, Fabio, Sandri, Maria Teresa, Civelli, Maurizio, Bottazzi, Barbara, Cucchi, GianFranco, Menatti, Elisabetta, Mangiavacchi, Maurizio, Condorelli, Gianluigi, Barbieri, Enrico, Gori, Stefania, Colombo, Alessandro, Curigliano, Giuseppe, Salvatici, Michela, Pastori, Paolo, Ghisoni, Francesco, Bianchi, Alessandra, Falci, Cristina, Cortesi, Pietro, Farolfi, Alberto, Monopoli, Anna, Milandri, Carlo, Bregni, Marco, Malossi, Alessandra, Nassiacos, Daniele, Verusio, Claudio, Staszewsky, Lidia, Leone, Roberto, Novelli, Deborah, Balconi, Giovanna, Nicolis, Enrico B., Franzosi, Maria Grazia, Masson, Serge, Garlanda, Cecilia, Mantovani, Alberto, Cipolla, Carlo M., Latini, Roberto

“…Aims A multicentre trial, ICOS‐ONE, showed increases above the upper limit of normality of cardiac troponin (cTn) in 27% of patients within 12 months after the…”
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Integrated Genomic, Functional, and Prognostic Characterization of Atypical Chronic Myeloid Leukemia by Fontana, Diletta, Ramazzotti, Daniele, Aroldi, Andrea, Redaelli, Sara, Magistroni, Vera, Pirola, Alessandra, Niro, Antonio, Massimino, Luca, Mastini, Cristina, Brambilla, Virginia, Bombelli, Silvia, Bungaro, Silvia, Morotti, Alessandro, Rea, Delphine, Stagno, Fabio, Martino, Bruno, Campiotti, Leonardo, Caocci, Giovanni, Usala, Emilio, Merli, Michele, Onida, Francesco, Bregni, Marco, Elli, Elena Maria, Fumagalli, Monica, Ciceri, Fabio, Perego, Roberto A., Pagni, Fabio, Mologni, Luca, Piazza, Rocco, Gambacorti‐Passerini, Carlo

“…Supplemental Digital Content is available for this article. Atypical chronic myeloid leukemia (aCML) is a BCR‐ABL1‐negative clonal disorder, which belongs to…”
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Innovative platforms for haploidentical stem cell transplantation: the role of unmanipulated donor graft by Ciceri, Fabio, Bregni, Marco, Peccatori, Jacopo

“…We exploited the dual positive effects of rapamycin to prevent GvHD and control malignant cells upon infusion of unmanipulated grafts from family…”
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Lymphocytes genetically modified to express tumor antigens target DCs in vivo and induce antitumor immunity by Russo, Vincenzo, Cipponi, Arcadi, Raccosta, Laura, Rainelli, Cristina, Fontana, Raffaella, Maggioni, Daniela, Lunghi, Francesca, Mukenge, Sylvain, Ciceri, Fabio, Bregni, Marco, Bordignon, Claudio, Traversari, Catia

“…The exploitation of the physiologic processing and presenting machinery of DCs by in vivo loading of tumor-associated antigens may improve the immunogenic…”
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Allogeneic hematopoietic stem cell transplantation in ovarian cancer—the EBMT experience by Bay, Jacques‐Olivier, Cabrespine‐Faugeras, Aurélie, Tabrizi, Reza, Blaise, Didier, Viens, Patrice, Ehninger, Gerhard, Bornhauser, Martin, Slavin, Shimon, Rosti, Giovanni, Peccatori, Jacopo, Demirer, Taner, Bregni, Marco

“…Although preliminary results suggest that allogeneic hematopoietic stem cell transplantation (allo HCT) for ovarian cancer (OC) is a feasible procedure, the…”
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Allogeneic Stem Cell Transplantation for Metastatic Renal Cell Cancer (RCC) by Bregni, Marco, Ciceri, Fabio, Peccatori, Jacopo

“…A variety of therapeutic options are now available for advanced renal cell cancer, including antiangiogenic and anti-mTOR agents. Allogeneic hematopoietic stem…”
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A Clinical Study of a Cell-Based MAGE-A3 Active Immunotherapy in Advanced Melanoma Patients by Russo, Vincenzo, Lunghi, Francesca, Fontana, Raffaella, Bregni, Marco

“…In this bi-institutional study, twenty-three stage IIIC-IV MAGE-A3(+) melanoma patients were vaccinated with M3TK-GML biweekly at three dose levels, with a…”
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4th Edition of the International Autologous and Allogeneic Cell Therapy for Solid Tumors (ATST) Meeting by Bregni, Marco, Childs, Richard W, Ueno, Naoto T

“…The fourth edition of the International Autologous and Allogeneic Cell Therapy for Solid Tumors (ATST) meeting was held in Venice, Italy, between March 31 and…”
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Molecular purging of multiple myeloma cells by ex-vivo culture and retroviral transduction of mobilized-blood CD34+ cells by Deola, Sara, Scaramuzza, Samantha, Birolo, Roberto Sciarretta, Cergnul, Massimiliano, Ficara, Francesca, Dando, Jonathan, Voena, Claudia, Vai, Sergio, Monari, Marta, Pogliani, Enrico, Corneo, Gianmarco, Peccatori, Jacopo, Selleri, Silvia, Bordignon, Claudio, Roncarolo, Maria Grazia, Aiuti, Alessandro, Bregni, Marco

“…Tumor cell contamination of the apheresis in multiple myeloma is likely to affect disease-free and overall survival after autografting. To purge myeloma…”
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Nivolumab and brain metastases in patients with advanced non-squamous non-small cell lung cancer by Crinò, Lucio, Bronte, Giuseppe, Bidoli, Paolo, Cravero, Paola, Minenza, Elisa, Cortesi, Enrico, Garassino, Marina C., Proto, Claudia, Cappuzzo, Federico, Grossi, Francesco, Tonini, Giuseppe, Sarobba, Maria Giuseppina, Pinotti, Graziella, Numico, Gianmauro, Samaritani, Riccardo, Ciuffreda, Libero, Frassoldati, Antonio, Bregni, Marco, Santo, Antonio, Piantedosi, Francovito, Illiano, Alfonso, De Marinis, Filippo, Tamberi, Stefano, Giannarelli, Diana, Delmonte, Angelo

“…Brain metastases are common among patients with non-squamous non-small-cell lung cancer (NSCLC) and result in a poor prognosis. Consequently, such patients are…”
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Anthracycline-induced cardiotoxicity: A multicenter randomised trial comparing two strategies for guiding prevention with enalapril: The International CardioOncology Society-one trial by Cardinale, Daniela, Latini, Roberto, Franzosi, Maria Grazia, Civelli, Maurizio, Cucchi, GianFranco, Menatti, Elisabetta, Mangiavacchi, Maurizio, Cavina, Raffaele, Gori, Stefania, Colombo, Alessandro, Curigliano, Giuseppe, Salvatici, Michela, Rizzo, Antonio, Ghisoni, Francesco, Bianchi, Alessandra, Falci, Cristina, Rocca, Andrea, Monopoli, Anna, Milandri, Carlo, Bregni, Marco, Sicuro, Marco, Giordano, Monica, Staszewsky, Lidia, Nicolis, Enrico B., Masson, Serge, Cipolla, Carlo M., Cipolla, C.M., Cardinale, D., Ciceri, F., Latini, R., Sandri, M.T., Maggioni, A.P., Labianca, R., Finzi, A., Vago, T., Civelli, M., Gramenzi, S., Masson, S., Balconi, G., Bernasconi, R., Salvatici, M., Nicolis, E., Magnoli, M., Buratti, M.G., Malossi, A., Sicuro, M., Thiebat, B., Corzani, A., Colecchia, S., Pellegrini, C., Bregni, M., Appio, L., Caico, I., G.Rossetti, Mesenzani, O., Campana, C., Giordano, M., Gilardoni, M., Scognamiglio, G., Corrado, G., Battagin, D., Monopoli, A., Giannessi, P.G., Zipoli, G., Ghisoni, F., Rizzo, A., Callegari, S., Sesenna, C., Colombo, A., G.Curigliano, Fodor, C., Cavina, R., Mazza, R., Vallerio, P., Marbello, L., Sala, E., Fragasso, G., Trinca, S., Rocca, A., Farolfi, A., Gori, S., Barbieri, E., Lanzoni, L., Falci, C., Bianchi, A., Mioranza, E., Re, F., Gaibazzi, N., Turina, M.C., Giaroli, F., Nassiacos, D., Verusio, C., Barco, B., Bertolini, A., Menatti, E., Sinagra, G., Aleksova, A., Pinotti, G., Gueli, R., Mongiardi, C.

“…Troponin changes over time have been suggested to allow for an early diagnosis of cardiac injury ensuing cancer chemotherapy; cancer patients with troponin…”
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Gene Therapy for Immunodeficiency Due to Adenosine Deaminase Deficiency by Aiuti, Alessandro, Cattaneo, Federica, Galimberti, Stefania, Benninghoff, Ulrike, Cassani, Barbara, Callegaro, Luciano, Scaramuzza, Samantha, Andolfi, Grazia, Mirolo, Massimiliano, Brigida, Immacolata, Tabucchi, Antonella, Carlucci, Filippo, Eibl, Martha, Aker, Memet, Slavin, Shimon, Al-Mousa, Hamoud, Al Ghonaium, Abdulaziz, Ferster, Alina, Duppenthaler, Andrea, Notarangelo, Luigi, Wintergerst, Uwe, Buckley, Rebecca H, Bregni, Marco, Marktel, Sarah, Valsecchi, Maria Grazia, Rossi, Paolo, Ciceri, Fabio, Miniero, Roberto, Bordignon, Claudio, Roncarolo, Maria-Grazia

“…Deficiency of adenosine deaminase (ADA) causes a form of severe combined immunodeficiency disease. This study shows that gene therapy in the form of…”
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