Search Results - "BRAU, Frédéric"
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Peribacteroid space acidification: a marker of mature bacteroid functioning in Medicago truncatula nodules
Published in Plant, cell and environment (01-11-2013)“…Legumes form a symbiotic interaction with Rhizobiaceae bacteria, which differentiate into nitrogen‐fixing bacteroids within nodules. Here, we investigated in…”
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Mixing and matching TREK/TRAAK subunits generate heterodimeric K2P channels with unique properties
Published in Proceedings of the National Academy of Sciences - PNAS (12-04-2016)“…The tandem of pore domain in a weak inwardly rectifying K⁺ channel (Twik)-related acid-arachidonic activated K⁺ channel (TRAAK) and Twik-related K⁺ channels…”
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M-Cube — towards correlative multi-scale light-sheet imaging using a compact, modular and moving illuminator
Published in EPJ Web of conferences (2024)“…The crossed arrangement of excitation and collection optics is the defining feature of selective plane illumination microscopes. It results in an axial…”
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Easing batch image processing from OMERO: a new toolbox for ImageJ [version 1; peer review: 2 approved]
Published in F1000 research (2022)“…The Open Microscopy Environment Remote Objects (OMERO) is an open source image manager used by many biologists to store, organize, view and share microscopy…”
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Easing batch image processing from OMERO: a new toolbox for ImageJ [version 2; peer review: 2 approved]
Published in F1000 research (2022)“…The Open Microscopy Environment Remote Objects (OMERO) is an open-source image manager used by many biologists to store, organize, view, and share microscopy…”
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6
New Insights Into the Role of Cav2 Protein Family in Calcium Flux Deregulation in Fmr1-KO Neurons
Published in Frontiers in molecular neuroscience (27-09-2018)“…Fragile X syndrome (FXS), the most common form of inherited intellectual disability and a leading cause of autism, results from the loss of expression of the…”
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A Single-Cell Atlas of the Human Healthy Airways
Published in American journal of respiratory and critical care medicine (15-12-2020)“…The respiratory tract constitutes an elaborate line of defense that is based on a unique cellular ecosystem. We aimed to investigate cell population…”
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Missense mutation of Fmr1 results in impaired AMPAR-mediated plasticity and socio-cognitive deficits in mice
Published in Nature communications (10-03-2021)“…Fragile X syndrome (FXS) is the most frequent form of inherited intellectual disability and the best-described monogenic cause of autism. CGG-repeat expansion…”
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FATE1 antagonizes calcium- and drug-induced apoptosis by uncoupling ER and mitochondria
Published in EMBO reports (01-09-2016)“…Several stimuli induce programmed cell death by increasing Ca 2+ transfer from the endoplasmic reticulum (ER) to mitochondria. Perturbation of this process has…”
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Stromal Cell Networks Regulate Lymphocyte Entry, Migration, and Territoriality in Lymph Nodes
Published in Immunity (Cambridge, Mass.) (01-12-2006)“…After entry into lymph nodes (LNs), B cells migrate to follicles, whereas T cells remain in the paracortex, with each lymphocyte type showing apparently random…”
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Mixing and matching TREK/TRAAK subunits generate heterodimeric K 2P channels with unique properties
Published in Proceedings of the National Academy of Sciences - PNAS (12-04-2016)“…Nearly 350 human genes encode ion channels. Posttranscriptional (alternative splicing, editing, and alternative translation initiation) and posttranslational…”
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Mechano-induced cell metabolism promotes microtubule glutamylation to force metastasis
Published in Cell metabolism (06-07-2021)“…Mechanical signals from the tumor microenvironment modulate cell mechanics and influence cell metabolism to promote cancer aggressiveness. Cells withstand…”
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13
In situ artificial contact sites (ISACS) between synthetic and endogenous organelle membranes allow for quantification of protein-tethering activities
Published in The Journal of biological chemistry (01-05-2022)“…Membrane contact sites are specialized areas where the membranes of two distinct organelles are physically connected and allow for the exchange of molecules…”
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Phosphodiesterase 2A inhibition corrects the aberrant behavioral traits observed in genetic and environmental preclinical models of Autism Spectrum Disorder
Published in Translational psychiatry (25-03-2022)“…Pharmacological inhibition of phosphodiesterase 2A (PDE2A), which catalyzes the hydrolysis of cyclic adenosine monophosphate (cAMP) and cyclic guanosine…”
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Involvment of cytosolic and mitochondrial GSK-3beta in mitochondrial dysfunction and neuronal cell death of MPTP/MPP-treated neurons
Published in PloS one (2009)“…Aberrant mitochondrial function appears to play a central role in dopaminergic neuronal loss in Parkinson's disease (PD). 1-methyl-4-phenylpyridinium iodide…”
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HIV Tat and cocaine interactively alter genome-wide DNA methylation and gene expression and exacerbate learning and memory impairments
Published in Cell reports (Cambridge) (03-05-2022)“…Cocaine use is a major comorbidity of HIV-associated neurocognitive disorder (HAND). In this study, we show that cocaine exposure worsens the learning and…”
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Sumoylation regulates FMRP-mediated dendritic spine elimination and maturation
Published in Nature communications (22-02-2018)“…Fragile X syndrome (FXS) is the most frequent inherited cause of intellectual disability and the best-studied monogenic cause of autism. FXS results from the…”
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Surface tension-driven sorting of human perilipins on lipid droplets
Published in The Journal of cell biology (02-12-2024)“…Perilipins (PLINs), the most abundant proteins on lipid droplets (LDs), display similar domain organization including amphipathic helices (AH). However, the…”
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Bidirectional regulation of synaptic SUMOylation by Group 1 metabotropic glutamate receptors
Published in Cellular and molecular life sciences : CMLS (01-07-2022)“…SUMOylation is a post-translational modification essential to cell homeostasis. A tightly controlled equilibrium between SUMOylation and deSUMOylation…”
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Involvment of Cytosolic and Mitochondrial GSK-3β in Mitochondrial Dysfunction and Neuronal Cell Death of MPTP/MPP+-Treated Neurons
Published in PloS one (11-05-2009)“…Aberrant mitochondrial function appears to play a central role in dopaminergic neuronal loss in Parkinson's disease (PD). 1-methyl-4-phenylpyridinium iodide…”
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