Search Results - "BRATT, Göran"

Population genomics of intrapatient HIV-1 evolution by Zanini, Fabio, Brodin, Johanna, Thebo, Lina, Lanz, Christa, Bratt, Göran, Albert, Jan, Neher, Richard A

“…Many microbial populations rapidly adapt to changing environments with multiple variants competing for survival. To quantify such complex evolutionary dynamics…”
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Development of type 2 diabetes and insulin resistance in people with HIV infection: Prevalence, incidence and associated factors by Bratt, Göran, Brännström, Johanna, Missalidis, Catharina, Nyström, Thomas

“…Background Diabetes and insulin resistance is an emerging issue in people with HIV. HIV-related mortality and morbidities have decreased markedly over the last…”
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Temporal trends in the Swedish HIV-1 epidemic: increase in non-B subtypes and recombinant forms over three decades by Neogi, Ujjwal, Häggblom, Amanda, Santacatterina, Michele, Bratt, Göran, Gisslén, Magnus, Albert, Jan, Sonnerborg, Anders

“…HIV-1 subtype B (HIV-1B) still dominates in resource-rich countries but increased migration contributes to changes in the global subtype distribution. Also,…”
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Treatment as prevention for HIV: a reality by Blaxhult, Anders, Bratt, Göran

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Trends in antiretroviral therapy and prevalence of HIV drug resistance mutations in Sweden 1997-2011 by Bontell, Irene, Häggblom, Amanda, Bratt, Göran, Albert, Jan, Sönnerborg, Anders

“…Describe trends in antiretroviral treatments and drug resistance mutations among Swedish HIV-patients over time 1997-2011. Treatment histories, viral…”
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Lymphogranuloma venereum rates increased and Chlamydia trachomatis genotypes changed among men who have sex with men in Sweden 2004-2016 by Isaksson, Jenny, Carlsson, Ola, Airell, Åsa, Strömdahl, Susanne, Bratt, Göran, Herrmann, Björn

“…This study aimed to determine the incidence of lymphogranuloma venereum (LGV) in Sweden since 2004 and to study in detail a consecutive number of Chlamydia…”
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Low prevalence of transmitted drug resistance in patients newly diagnosed with HIV-1 infection in Sweden 2003-2010 by Karlsson, Annika, Björkman, Per, Bratt, Göran, Ekvall, Håkan, Gisslén, Magnus, Sönnerborg, Anders, Mild, Mattias, Albert, Jan

“…Transmitted drug resistance (TDR) is a clinical and epidemiological problem because it may contribute to failure of antiretroviral treatment. The prevalence of…”
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Establishment and stability of the latent HIV-1 DNA reservoir by Brodin, Johanna, Zanini, Fabio, Thebo, Lina, Lanz, Christa, Bratt, Göran, Neher, Richard A, Albert, Jan

“…HIV-1 infection cannot be cured because the virus persists as integrated proviral DNA in long-lived cells despite years of suppressive antiretroviral therapy…”
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Longitudinal ultradeep characterization of HIV type 1 R5 and X4 subpopulations in patients followed from primary infection to coreceptor switch by Hedskog, Charlotte, Brodin, Johanna, Heddini, Alexander, Bratt, Göran, Albert, Jan, Mild, Mattias

“…In early infection HIV-1 generally uses the CCR5 coreceptor. During disease progression the coreceptor use switches to include CXCR4 in approximately 70% of…”
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Cellular cytotoxic response induced by DNA vaccination in HIV-1-infected patients by Calarota, Sandra, Bratt, Göran, Nordlund, Siv, Hinkula, Jorma, Leandersson, Ann-Charlotte, Sandström, Eric, Wahren, Britta

“…DNA vaccination is known to generate immune responses against HIV-1 in animal models. We aimed to assess the efficacy of DNA vaccination in induction of immune…”
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A nonsense mutation (428G→A) in the fucosyltransferase FUT2 gene affects the progression of HIV-1 infection by KINDBERG, Elin, HEJDEMAN, Bo, BRATT, Göran, WAHREN, Britta, LINDBLOM, Bertil, HINKULA, Jorma, SVENSSON, Lennart

“…The human FUT2 gene encodes the alpha(1,2)fucosyltransferase that determines secretor status. Homozygous for the nonsense mutation are called non-secretors and…”
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Orally exposed uninfected individuals have systemic anti-HIV responses associating with partners' viral load by HASSELROT, Klara, BRATT, Göran, HIRBOD, Taha, SÄBERG, Pär, EHNLUND, Mariethe, LOPALCO, Lucia, SANDSTRÖM, Eric, BROLIDEN, Kristina

“…To determine whether oral HIV-1 exposure incites a persistent systemic anti-HIV-1 response in exposed uninfected individuals of discordant couples of men who…”
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Induction of systemic HIV-1-specific cellular immune responses by oral exposure in the uninfected partner of discordant couples by PEREZ, Carina L, HASSELROT, Klara, BRATT, Göran, BROLIDEN, Kristina, KARLSSON, Annika C

“…Previous studies have identified HIV-specific T-cell responses in HIV-exposed uninfected individuals (EUI). However, so far no study has investigated exposure…”
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HIV-1 exposed uninfected men who have sex with men have increased levels of salivary CC-chemokines associated with sexual behavior by HASSELROT, Klara, BRATT, Göran, DUVEFELT, Kristina, HIRBOD, Taha, SANDSTRÖM, Eric, BROLIDEN, Kristina

“…To determine whether soluble molecules with known anti-HIV-1 activity are increased in saliva of HIV-1 exposed uninfected individuals of discordant couples of…”
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Factors associated with suboptimal antiretroviral therapy adherence to dose, schedule, and dietary instructions by Nilsson Schönnesson, Lena, Williams, Mark L, Ross, Michael W, Bratt, Göran, Keel, Blair

“…The purpose of this study was to assess the degree of suboptimal antiretroviral therapy adherence to dose, schedule, and dietary instructions and to examine…”
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Hypofibrinolytic State in HIV-1-Infected Patients Treated With Protease Inhibitor-Containing Highly Active Antiretroviral Therapy by Koppel, Kristina, Bratt, Göran, Schulman, Sam, Bylund, Håkan, Sandström, Eric

“…Decreased insulin sensitivity, hyperlipidemia, and body fat changes are considered as risk factors for coronary heart disease (CHD). A clustering of such…”
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The two-year impact of first generation protease inhibitor based antiretroviral therapy (PI-ART) on health-related quality of life by Eriksson, Lars E, Bratt, Göran A, Sandström, Eric, Nordström, Gun

“…Protease inhibitor based antiretroviral therapy (PI-ART) was introduced in 1996 and has greatly reduced the incidence of HIV-related morbidity and mortality in…”
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Dynamics of HIV-1 quasispecies during antiviral treatment dissected using ultra-deep pyrosequencing by Hedskog, Charlotte, Mild, Mattias, Jernberg, Johanna, Sherwood, Ellen, Bratt, Göran, Leitner, Thomas, Lundeberg, Joakim, Andersson, Björn, Albert, Jan

“…Ultra-deep pyrosequencing (UDPS) allows identification of rare HIV-1 variants and minority drug resistance mutations, which are not detectable by standard…”
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Lipoatrophy of the Footpad in HIV-Treated Patients Is Associated With Increased PAI-1 by Eriksson, Lars E., Nilsson Schönnesson, Lena, Bratt, Göran A.

“…Purpose: To describe lipoatrophy of the plantar pedis fat pads in human immunodeficiency virus (HIV) patients with or without long-term antiretroviral therapy…”
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Recent increased identification and transmission of HIV-1 unique recombinant forms in Sweden by Neogi, Ujjwal, Siddik, Abu Bakar, Kalaghatgi, Prabhav, Gisslén, Magnus, Bratt, Göran, Marrone, Gaetano, Sönnerborg, Anders

“…A temporal increase in non-B subtypes has earlier been described in Sweden by us and we hypothesized that this increased viral heterogeneity may become a…”
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