Search Results - "BRATER, D. C"

Factors Associated With Exacerbation of Heart Failure Include Treatment Adherence and Health Literacy Skills by Murray, MD, Tu, W, Wu, J, Morrow, D, Smith, F, Brater, DC

“…We determined the factors associated with exacerbation of heart failure, using a cohort (n = 192) nested within a randomized trial at a university‐affiliated…”
Get full text

Drug Dosing in Patients With Impaired Renal Function by Brater, DC

“…Renal function can affect disposition and response to drugs in a variety of ways. This review discusses the principles underlying such responses, with…”
Get full text

Diuretic Therapy by Brater, D. Craig

“…Diuretic drugs are widely used for the treatment of patients with edema. Among these drugs, loop diuretics such as furosemide are perhaps the most frequently…”
Get full text

Social Support and Health-Related Quality of Life in Chronic Heart Failure Patients by Bennett, S J, Perkins, S M, Lane, K A, Deer, M, Brater, D C, Murray, M D

“…Objectives: Objectives of this study were to: (1) describe perceived social support during a baseline hospitalization and 12 months later among heart failure…”
Get full text

Effect of cyclooxygenase-2 inhibition on renal function in elderly persons receiving a low-salt diet : A randomized, controlled trial by SWAN, S. K, RUDY, D. W, GUMBS, C. P, EBEL, D. L, HUI QUAN, LARSON, P. J, SCHWARTZ, J. I, MUSLINER, T. A, GERTZ, B. J, BRATER, D. C, YAO, S.-L, LASSETER, K. C, RYAN, C. F, BUECHEL, K. L, LAMBRECHT, L. J, PINTO, M. B, DILZER, S. C, OBRDA, O, SUNDBLAD, K. J

“…Most nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit both cyclooxygenase-1 (COX-1), whose inhibition is associated with gastrointestinal ulceration, and…”
Get full text

Renal toxicity of the nonsteroidal anti-inflammatory drugs by Murray, M D, Brater, D C

“…NSAIDs pose little threat of renal insult in normal, healthy persons at therapeutic dosages. However, NSAID administration to susceptible persons may cause…”
Get full text

The interaction of diltiazem with lovastatin and pravastatin by Azie, Nkechi E., Brater, D. Craig, Becker, Paula A., Jones, David R., Hall, Stephen D.

“…Background Lovastatin is oxidized by cytochrome P4503A to active metabolites but pravastatin is active alone and is not metabolized by cytochrome P450…”
Get full text

The interaction of diltiazem with simvastatin by Mousa, Omaima, Brater, D. Craig, Sundblad, Kimberly J., Hall, Stephen D.

“…Background Simvastatin is an inhibitor of 3‐hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) reductase that is used as a cholesterol‐lowering agent and is…”
Get full text

Pharmacology of diuretics by Brater, D C

“…The diuretics in our therapeutic armamentarium have predictable effects based on their nephron sites of action. All but spironolactone must reach the lumen or…”
Get more information

Bioavailability, pharmacokinetics, and pharmacodynamics of torsemide and furosemide in patients with congestive heart failure by Vargo, D L, Kramer, W G, Black, P K, Smith, W B, Serpas, T, Brater, D C

“…The bioavailability, pharmacokinetics, and pharmacodynamics of torsemide (10 mg orally and intravenously) and furosemide (40 mg orally and 20 mg intravenously)…”
Get more information

Improving treatment of late life depression in primary care: a randomized clinical trial by Callahan, C M, Hendrie, H C, Dittus, R S, Brater, D C, Hui, S L, Tierney, W M

“…Facilitate primary care physicians' compliance with recommended standards of care for late life depression by reducing barriers to recognition and treatment…”
Get more information

Clinical pharmacology in the Middle Ages: Principles that presage the 21st century by Brater, D. Craig, Daly, Walter J.

Get full text

Clinical pharmacology of loop diuretics by BRATER, D. C

“…The clinical pharmacology of torasemide, bumetanide, piretanide and furosemide (frusemide) is discussed. These drugs share a similar mechanism of action in…”
Get full text

Stereoselective pharmacokinetics of ketoprofen and ketoprofen glucuronide in end‐stage renal disease: evidence for a ‘futile cycle’ of elimination by GRUBB, N. G, RUDY, D. W, BRATER, D. C, HALL, S. D

“…Aims To assess if futile cycling of ketoprofen occurs in patients with decreased renal function. Methods Ketoprofen was administered to six…”
Get full text

Defining hypercalciuria in nephrolithiasis by Pak, Charles Y.C., Sakhaee, Khashayar, Moe, Orson W., Poindexter, John, Adams-Huet, Beverley, with Colleagues

“…The classic definition of hypercalciuria, an upper normal limit of 200mg/day, is based on a constant diet restricted in calcium, sodium, and animal protein;…”
Get full text

Loop diuretics : translating pharmacokinetic properties into improved clinical outcomes by BRATER, D. C

Get full text

Stereoselective metabolism of ibuprofen in humans: administration of R-, S- and racemic ibuprofen by Rudy, A C, Knight, P M, Brater, D C, Hall, S D

“…Using stable isotope methodology, we studied the effect of the enantiomeric composition of dosage form on ibuprofen metabolism. Eight healthy human subjects…”
Get more information

Benefits and risks of torasemide in congestive heart-failure and essential hypertension by BRATER, D. C

“…Torasemide is a lipophilic anilinopyridine sulphonylurea derivative that acts as a high ceiling loop diuretic and has been used for the treatment of both acute…”
Get full text

Clinical pharmacology of loop diuretics in health and disease by Brater, D C

“…There are differences in metabolism and excretion of the loop diuretics which extrapolate to differences in pharmacokinetic behaviour in different disease…”
Get more information

Variable Furosemide Absorption and Poor Predictability of Response in Elderly Patients by Murray, Michael D., Haag, Kathy M., b́lack, Paula K., Hall, Stephen D., Brater, D. Craig

“…Study Objectives. To determine the between‐ and within‐patient variability of furosemide bioavailability and natriuretic response, and whether four marketed…”
Get full text