Search Results - "BRANCO DE BARROS, André Luis"
-
1
Investigation of the Antitumor Activity and Toxicity of Tumor-Derived Exosomes Fused with Long-Circulating and pH-Sensitive Liposomes Containing Doxorubicin
Published in Pharmaceutics (22-10-2022)“…Exosome–liposome hybrid nanocarriers containing chemotherapeutic agents have been developed to enhance drug delivery, improve the efficacy of the treatment of…”
Get full text
Journal Article -
2
Hybrid Nanosystem Formed by DOX-Loaded Liposomes and Extracellular Vesicles from MDA-MB-231 Is Effective against Breast Cancer Cells with Different Molecular Profiles
Published in Pharmaceutics (01-06-2024)“…Drug delivery selectivity is a challenge for cancer treatment. A hybrid pegylated pH-sensitive liposome-extracellular vesicle isolated from human breast cancer…”
Get full text
Journal Article -
3
Co-Encapsulation of Simvastatin and Doxorubicin into pH-Sensitive Liposomes Enhances Antitumoral Activity in Breast Cancer Cell Lines
Published in Pharmaceutics (21-01-2023)“…Doxorubicin (DOX) is a potent chemotherapeutic drug used as the first line in breast cancer treatment; however, cardiotoxicity is the main drawback of the…”
Get full text
Journal Article -
4
Potential of mucoadhesive nanocapsules in drug release and toxicology in zebrafish
Published in PloS one (24-09-2020)“…Mucoadhesive polymeric nanocapsules have attracted interest of researchers from different fields from natural sciences because of their ability to interact…”
Get full text
Journal Article -
5
Gold-Loaded Polymeric Micelles for Computed Tomography-Guided Radiation Therapy Treatment and Radiosensitization
Published in ACS nano (28-01-2014)“…Gold nanoparticles (AuNPs) have generated interest as both imaging and therapeutic agents. AuNPs are attractive for imaging applications since they are…”
Get full text
Journal Article -
6
[99mTc]Tc-Phosphate-buffer system as a potential tracer for bone imaging
Published in Journal of radioanalytical and nuclear chemistry (01-08-2021)“…In this study, phosphate-buffered saline solution (PBS) was successfully radiolabeled with technetium-99m. The biodistribution profile and bone accumulation of…”
Get full text
Journal Article -
7
CPP-Ts: a new intracellular calcium channel modulator and a promising tool for drug delivery in cancer cells
Published in Scientific reports (03-10-2018)“…Scorpion sting envenoming impacts millions of people worldwide, with cardiac effects being one of the main causes of death on victims. Here we describe the…”
Get full text
Journal Article -
8
Ferri–Liposomes: Preformulation and Selective Cytotoxicity against A549 Lung Cancer Cells
Published in Pharmaceutics (13-05-2021)“…Liposomes have become successful nanostructured systems used in clinical practices. These vesicles are able to carry important drug loadings with noteworthy…”
Get full text
Journal Article -
9
Nuclear factor kappa B expression in non-small cell lung cancer
Published in Biomedicine & pharmacotherapy (01-11-2023)“…In this mini-review, we discuss the role of NF-κB, a proinflammatory transcription factor, in the expression of genes involved in inflammation, proliferation,…”
Get full text
Journal Article -
10
pH-responsive and folate-coated liposomes encapsulating irinotecan as an alternative to improve efficacy of colorectal cancer treatment
Published in Biomedicine & pharmacotherapy (01-12-2021)“…Irinotecan (IRN) is a semisynthetic derivative of camptothecin that acts as a topoisomerase I inhibitor. IRN is used worldwide for the treatment of several…”
Get full text
Journal Article -
11
Recent advances and limitations in the application of kahalalides for the control of cancer
Published in Biomedicine & pharmacotherapy (01-04-2022)“…Since the discovery of the kahalalide family of marine depsipeptides in 1993, considerable work has been done to develop these compounds as new and…”
Get full text
Journal Article -
12
Thermosensitive Nanosystems Associated with Hyperthermia for Cancer Treatment
Published in Pharmaceuticals (Basel, Switzerland) (25-11-2019)“…Conventional chemotherapy regimens have limitations due to serious adverse effects. Targeted drug delivery systems to reduce systemic toxicity are a powerful…”
Get full text
Journal Article -
13
Alpha-tocopheryl succinate and doxorubicin-loaded liposomes improve drug uptake and tumor accumulation in a murine breast tumor model
Published in Biomedicine & pharmacotherapy (01-09-2023)“…Liposomes composed of a rigid bilayer have high plasma stability; however, they can be challenged in efficacy due to complications in releasing the…”
Get full text
Journal Article -
14
Scintigraphic imaging and increment in mice survival using theranostic liposomes based on Gadolinium-159
Published in Journal of drug delivery science and technology (01-12-2015)“…Theranostic nanosystems have attracted the attention of many scientists in worldwide due to its ability to accumulate and release selectively, in specific…”
Get full text
Journal Article -
15
Aptamers directly radiolabeled with technetium-99m as a potential agent capable of identifying carcinoembryonic antigen (CEA) in tumor cells T84
Published in Bioorganic & medicinal chemistry letters (15-04-2014)“…Aptamers are small oligonucleotides that are selected to bind with high affinity and specificity to a target molecule. Aptamers are emerging as a new class of…”
Get full text
Journal Article -
16
Mesoporous silica SBA-16/hydroxyapatite-based composite for ciprofloxacin delivery to bacterial bone infection
Published in Journal of sol-gel science and technology (01-02-2018)“…The development of systems that can prevent infections and also ensure bone integration as well as regeneration have been of great interest for pharmaceutical…”
Get full text
Journal Article -
17
Synthesis and antimicrobial evaluation of two peptide LyeTx I derivatives modified with the chelating agent HYNIC for radiolabeling with technetium-99m
Published in The journal of venomous animals and toxins including tropical diseases (22-04-2016)“…Current diagnostic methods and imaging techniques are not able to differentiate septic and aseptic inflammation. Thus, reliable methods are sought to provide…”
Get full text
Journal Article -
18
Radiolabeling of cidofovir with technetium-99m and biodistribution studies
Published in Brazilian Journal of Pharmaceutical Sciences (01-01-2020)“…Radiolabeling cidofovir with technetium-99m (99mTc-CDV) is an innovative procedure that enables real-time monitoring of the drug. Essays were performed in…”
Get full text
Journal Article -
19
Long-Circulating and pH-Sensitive Liposome Preparation Trapping a Radiotracer for Inflammation Site Detection
Published in Journal of nanoscience and nanotechnology (01-06-2015)“…Inflammatory and infectious diseases are one of the most common causes of mortality and morbidity. This paper aimed to prepare and to evaluate the ability of…”
Get more information
Journal Article -
20
Sclareol is a potent enhancer of doxorubicin: Evaluation of the free combination and co-loaded nanostructured lipid carriers against breast cancer
Published in Life sciences (1973) (01-09-2019)“…In this work, it was sought to determine if there was synergism between doxorubicin (DOX), a well-known antineoplastic, and sclareol (SC), a diterpene from…”
Get full text
Journal Article