Search Results - "BRANCH, R. A"

Evaluation of flurbiprofen urinary ratios as in vivo indices for CYP2C9 activity by Zgheib, N. K., Frye, R. F., Tracy, T. S., Romkes, M., Branch, R. A.

“…Aims We investigated flurbiprofen pharmacokinetics in 12 volunteers to develop a phenotypic trait measure that correlates with the fractional clearance to…”
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River Plume Liftoff Dynamics and Surface Expressions by Branch, R. A., Horner‐Devine, A. R., Kumar, N., Poggioli, A. R.

“…The water surface expression of liftoff and its dependence on discharge are examined using numerical simulations with the Regional Ocean Modeling System…”
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Validation of the five-drug "Pittsburgh cocktail" approach for assessment of selective regulation of drug-metabolizing enzymes by Frye, Reginald F., Matzke, Gary R., Adedoyin, Adedayo, Porter, James A., Branch, Robert A.

“…Objectives To determine whether the probe drugs caffeine, chlorzoxazone, dapsone, debrisoquin (INN, debrisoquine), and mephenytoin can be simultaneously…”
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Pharmacokinetic profile of ABELCET (amphotericin B lipid complex injection): combined experience from phase I and phase II studies by ADEDOYIN, A, BERNARDO, J. F, ANAISSIE, E, LOPEZ-BERESTEIN, G, LLANOS-CUENTAS, A, BOYLE, A, BRANCH, R. A, SWENSON, C. E, BOLSACK, L. E, HORWITH, G, DEWIT, S, KELLY, E, KLASTERKSY, J, SCULIER, J. P, DEVALERIOLA, D

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Development of dapsone toxicity in patients with inflammatory dermatoses: Activity of acetylation and hydroxylation of dapsone as risk factors by Bluhm, Ranata E., Adedoyin, Adedayo, McCarver, D. G., Branch, Robert A.

“…Background Alternative independent routes of dapsone metabolism include N‐hydroxylation to the hydroxylamine, a potentially toxic metabolite, by cytochrome…”
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Effectiveness of antipsychotic therapy in a naturalistic setting : A comparison between risperidone, perphenazine, and haloperidol by COLEY, K. C, CARTER, C. S, DAPOS, S. V, MAXWELL, R, WILSON, J. W, BRANCH, R. A

“…Therapeutic ineffectiveness and noncompliance with antipsychotic agents are major contributors to rehospitalization in patients with psychotic disorders. It is…”
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Estrogen and Tamoxifen Metabolites Protect Smooth Muscle Cell Membrane Phospholipids Against Peroxidation and Inhibit Cell Growth by Dubey, Raghvendra K, Tyurina, Yulia Y, Tyurin, Vladimir A, Gillespie, Delbert G, Branch, Robert A, Jackson, Edwin K, Kagan, Valerian E

“…The goal of this study was to test the hypothesis that antioxidant estrogens, by a mechanism independent of the estrogen receptor, protect phospholipids…”
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Duloxetine pharmacokinetics in cirrhotics compared with healthy subjects by Suri, A, Reddy, S, Gonzales, C, Knadler, M P, Branch, R A, Skinner, M H

“…To compare the pharmacokinetics of single-dose duloxetine in cirrhotic and healthy subjects. An open-label inpatient study compared duloxetine pharmacokinetics…”
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Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian populations by Nakamura, K, Goto, F, Ray, W A, McAllister, C B, Jacqz, E, Wilkinson, G R, Branch, R A

“…Interethnic differences in debrisoquin and mephenytoin hydroxylation have been compared between normal white (n = 183) and Japanese (n = 100) subjects with the…”
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Selective effect of liver disease on the activities of specific metabolizing enzymes: Investigation of cytochromes P450 2C19 and 2D6 by Adedoyin, Adedayo, Arns, Patricia A., Richards, W.O., Wilkinson, Grant R., Branch, Robert A.

“…Background and Objectives Drug metabolism is influenced by liver disease because of the central role that the liver plays in metabolic activities in the body…”
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Chloroquine modulation of specific metabolizing enzymes activities: investigation with selective five drug cocktail by Adedoyin, Adedayo, Frye, Reginald F., Mauro, Kelly, Branch, Robert A.

“…Aims  The aim of this study was to investigate whether chloroquine can inhibit drug metabolism in humans, if such inhibition is general or selective for…”
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Human liver microsomal N-hydroxylation of dapsone by cytochrome P-4503A4 by Fleming, C M, Branch, R A, Wilkinson, G R, Guengerich, F P

“…One of the major routes of elimination of dapsone (4,4'-diaminodiphenylsulfone) is by N-oxidation, to produce a hydroxylamine metabolite. The specific form of…”
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Drugs in liver disease by Branch, Robert A.

“…Clinical Pharmacology & Therapeutics (1998) 64, 462–465; doi:…”
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A Pharmacokinetic Study of Amphotericin B Lipid Complex Injection (Abelcet) in Patients with Definite or Probable Systemic Fungal Infections by ADEDOYIN, Adedayo, SWENSON, Christine E, BOLCSAK, Lois E, HELLMANN, Andrzej, RADOWSKA, Danuta, HORWITH, Gary, JANOFF, Andrew S, BRANCH, Robert A

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Genetic polymorphism of S-mephenytoin hydroxylation by Wilkinson, G R, Guengerich, F P, Branch, R A

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Mephenytoin hydroxylation deficiency in Caucasians: frequency of a new oxidative drug metabolism polymorphism by Wedlund, P J, Aslanian, W S, McAllister, C B, Wilkinson, G R, Branch, R A

“…The ability of normal subjects to hydroxylate mephenytoin (100 mg) or debrisoquine (10 mg) after oral dosing was investigated in 156 unrelated Caucasians…”
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Effect of salt supplementation on amphotericin B nephrotoxicity by Llanos, Alejandro, Cieza, Javier, Bernardo, Jose, Echevarria, Juan, Biaggioni, Italo, Sabra, Ramzi, Branch, Robert A.

“…Effect of salt supplementation on amphotericin B nephrotoxicity. It has been suggested that salt loading protects against amphotericin B-in-duced…”
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Frequency distribution of dapsone N-hydroxylase, a putative probe for P4503A4 activity, in a white population by May, D G, Porter, J, Wilkinson, G R, Branch, R A

“…Phenotypic trait values in 166 healthy white subjects (age range, 18 to 88 years) were determined for dapsone N-hydroxylation, dapsone N-acetylation,…”
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Amphotericin B protects cis-parinaric acid against peroxyl radical-induced oxidation: amphotericin B as an antioxidant by OSAKA, K, RITOV, V. B, BERNARDO, J. F, BRANCH, R. A, KAGAN, V. E

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Changing physician prescribing behavior: the community-acquired pneumonia intervention trial by Coley, KC, Skledar, SJ, Fine, MJ, Yealy, DM, Gleason, PP, Ryan, ML, Kapoor, W, Branch, RA

“…The Notes section welcomes the following types of contributions: (1) practical innovations or solutions to everyday practice problems, (2) substantial updates…”
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