Search Results - "BRAIN, Etienne"

21-Gene Assay to Inform Chemotherapy Benefit in Node-Positive Breast Cancer by Kalinsky, Kevin, Barlow, William E, Gralow, Julie R, Meric-Bernstam, Funda, Albain, Kathy S, Hayes, Daniel F, Lin, Nancy U, Perez, Edith A, Goldstein, Lori J, Chia, Stephen K.L, Dhesy-Thind, Sukhbinder, Rastogi, Priya, Alba, Emilio, Delaloge, Suzette, Martin, Miguel, Kelly, Catherine M, Ruiz-Borrego, Manuel, Gil-Gil, Miguel, Arce-Salinas, Claudia H, Brain, Etienne G.C, Lee, Eun-Sook, Pierga, Jean-Yves, Bermejo, Begoña, Ramos-Vazquez, Manuel, Jung, Kyung-Hae, Ferrero, Jean-Marc, Schott, Anne F, Shak, Steven, Sharma, Priyanka, Lew, Danika L, Miao, Jieling, Tripathy, Debasish, Pusztai, Lajos, Hortobagyi, Gabriel N

“…Five-year invasive disease–free survival was similar among postmenopausal women with hormone-receptor–positive, HER2-negative breast cancer, one to three…”
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Updated recommendations regarding the management of older patients with breast cancer: a joint paper from the European Society of Breast Cancer Specialists (EUSOMA) and the International Society of Geriatric Oncology (SIOG) by Biganzoli, Laura, Battisti, Nicolò Matteo Luca, Wildiers, Hans, McCartney, Amelia, Colloca, Giuseppe, Kunkler, Ian H, Cardoso, Maria-João, Cheung, Kwok-Leung, de Glas, Nienke Aafke, Trimboli, Rubina M, Korc-Grodzicki, Beatriz, Soto-Perez-de-Celis, Enrique, Ponti, Antonio, Tsang, Janice, Marotti, Lorenza, Benn, Karen, Aapro, Matti S, Brain, Etienne G C

“…Breast cancer is increasingly prevalent in older adults and is a substantial part of routine oncology practice. However, management of breast cancer in this…”
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Phase II Trial of Weekly Paclitaxel for Unresectable Angiosarcoma: The ANGIOTAX Study by PENEL, Nicolas, BINH NGUYEN BUI, ISAMBERT, Nicolas, PEYRADE, Frédéric, CHEVREAU, Christine, BOMPAS, Emmanuelle, BRAIN, Etienne G. C, BLAY, Jean-Yves, BAY, Jacques-Olivier, CUPISSOL, Didier, RAY-COQUARD, Isabelle, PIPERNO-NEUMANN, Sophie, KERBRAT, Pierre, FOURNIER, Charles, TAIEB, Sophie, JIMENEZ, Marta

“…The objective of this phase II trial was to assess the efficacy and toxicity of weekly paclitaxel for patients with metastatic or unresectable angiosarcoma…”
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All oncologists are geriatric oncologists by Brain, Etienne G.C.

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70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer by Cardoso, Fatima, van’t Veer, Laura J, Bogaerts, Jan, Slaets, Leen, Viale, Giuseppe, Delaloge, Suzette, Pierga, Jean-Yves, Brain, Etienne, Causeret, Sylvain, DeLorenzi, Mauro, Glas, Annuska M, Golfinopoulos, Vassilis, Goulioti, Theodora, Knox, Susan, Matos, Erika, Meulemans, Bart, Neijenhuis, Peter A, Nitz, Ulrike, Passalacqua, Rodolfo, Ravdin, Peter, Rubio, Isabel T, Saghatchian, Mahasti, Smilde, Tineke J, Sotiriou, Christos, Stork, Lisette, Straehle, Carolyn, Thomas, Geraldine, Thompson, Alastair M, van der Hoeven, Jacobus M, Vuylsteke, Peter, Bernards, René, Tryfonidis, Konstantinos, Rutgers, Emiel, Piccart, Martine

“…In a study in women with early breast cancer, those with high-risk clinical features and a low-risk gene-expression profile were assigned to chemotherapy or no…”
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Why and how moving forward in clinical research for the older cancer patients? by Brain, Etienne G C

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Systemic Therapy in Older Patients With High-Risk Disease by Brain, Etienne G C

“…Adjuvant systemic treatments for older patients with breast cancer require constant dose or schedule adjustments of standards established for younger ones…”
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Clinical utility of circulating tumour cell-based monitoring of late-line chemotherapy for metastatic breast cancer: the randomised CirCe01 trial by Cabel, Luc, Berger, Frédérique, Cottu, Paul, Loirat, Delphine, Rampanou, Aurore, Brain, Etienne, Cyrille, Stacy, Bourgeois, Hugues, Kiavue, Nicolas, Deluche, Elise, Ladoire, Sylvain, Campone, Mario, Pierga, Jean-Yves, Bidard, Francois-Clement

“…Background CirCe01 trial aimed to assess the clinical utility of circulating tumour cell (CTC)-based monitoring in metastatic breast cancer (MBC) patients…”
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PORTRET, a more inclusive portrait of the older population with breast cancer by Brain, Etienne G C

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Management of elderly patients with breast cancer: updated recommendations of the International Society of Geriatric Oncology (SIOG) and European Society of Breast Cancer Specialists (EUSOMA) by Biganzoli, Laura, Dr, Wildiers, Hans, MD, Oakman, Catherine, MD, Marotti, Lorenza, BSc, Loibl, Sibylle, MD, Kunkler, Ian, FRCR, Reed, Malcolm, Prof, Ciatto, Stefano, MD, Voogd, Adri C, PhD, Brain, Etienne, MD, Cutuli, Bruno, MD, Terret, Catherine, MD, Gosney, Margot, Prof, Aapro, Matti, MD, Audisio, Riccardo, Prof

“…Summary As the mean age of the global population increases, breast cancer in older individuals will be increasingly encountered in clinical practice…”
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COVID-19 in breast cancer patients: a cohort at the Institut Curie hospitals in the Paris area by Vuagnat, Perrine, Frelaut, Maxime, Ramtohul, Toulsie, Basse, Clémence, Diakite, Sarah, Noret, Aurélien, Bellesoeur, Audrey, Servois, Vincent, Hequet, Delphine, Laas, Enora, Kirova, Youlia, Cabel, Luc, Pierga, Jean-Yves, Bozec, Laurence, Paoletti, Xavier, Cottu, Paul, Bidard, François-Clément

“…Cancer patients have been reported to be at higher risk of COVID-19 complications and deaths. We report the characteristics and outcome of patients diagnosed…”
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Plasma thymidine kinase 1 activity and outcome of ER+ HER2- metastatic breast cancer patients treated with palbociclib and endocrine therapy by Cabel, Luc, Rosenblum, Dan, Lerebours, Florence, Brain, Etienne, Loirat, Delphine, Bergqvist, Mattias, Cottu, Paul, Donnadieu, Anne, Bethune, Anne, Kiavue, Nicolas, Rodrigues, Manuel, Pierga, Jean-Yves, Tanguy, Marie-Laure, Bidard, François-Clément

“…Previous cohort studies have reported plasma TK1 activity (pTKa) as a potential prognostic biomarker in estrogen receptor-positive (ER+) HER2-negative (HER2-)…”
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Individualizing Surveillance Mammography for Older Patients After Treatment for Early-Stage Breast Cancer: Multidisciplinary Expert Panel and International Society of Geriatric Oncology Consensus Statement by Freedman, Rachel A, Minami, Christina A, Winer, Eric P, Morrow, Monica, Smith, Alexander K, Walter, Louise C, Sedrak, Mina S, Gagnon, Haley, Perilla-Glen, Adriana, Wildiers, Hans, Wildes, Tanya M, Lichtman, Stuart M, Loh, Kah Poh, Brain, Etienne G C, Ganschow, Pamela S, Hunt, Kelly K, Mayer, Deborah K, Ruddy, Kathryn J, Jagsi, Reshma, Lin, Nancy U, Canin, Beverly, LeStage, Barbara K, Revette, Anna C, Schonberg, Mara A, Keating, Nancy L

“…There is currently no guidance on how to approach surveillance mammography for older breast cancer survivors, particularly when life expectancy is limited. To…”
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First-line chemoimmunotherapy in metastatic breast carcinoma: combination of paclitaxel and IMP321 (LAG-3Ig) enhances immune responses and antitumor activity by Brignone, Chrystelle, Gutierrez, Maya, Mefti, Fawzia, Brain, Etienne, Jarcau, Rosana, Cvitkovic, Frédérique, Bousetta, Nabil, Medioni, Jacques, Gligorov, Joseph, Grygar, Caroline, Marcu, Manon, Triebel, Frédéric

“…IMP321 is a recombinant soluble LAG-3Ig fusion protein that binds to MHC class II with high avidity and mediates APC and then antigen-experienced memory CD8+ T…”
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Management of breast cancer in elderly individuals: recommendations of the International Society of Geriatric Oncology by Wildiers, Hans, Dr, Prof, Kunkler, Ian, FRCPE, Biganzoli, Laura, MD, Fracheboud, Jacques, MD, Vlastos, George, Prof, Bernard-Marty, Chantal, MD, Hurria, Arti, MD, Extermann, Martine, Prof, Girre, Véronique, MD, Brain, Etienne, MD, Audisio, Riccardo A, FRSC, Bartelink, Harry, Prof, Barton, Mary, MD, Giordano, Sharon H, MD, Muss, Hyman, MD, Aapro, Matti, MD

“…Summary Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer mortality in women worldwide. Elderly individuals make up a large…”
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Impact of liposomal doxorubicin-based adjuvant chemotherapy on autonomy in women over 70 with hormone-receptor-negative breast carcinoma: A French Geriatric Oncology Group (GERICO) phase II multicentre trial by Brain, Etienne G.C, Mertens, Cécile, Girre, Véronique, Rousseau, Frédérique, Blot, Emmanuel, Abadie, Sophie, Uwer, Lionel, Bourbouloux, Emmanuelle, Van Praagh-Doreau, Isabelle, Mourey, Loic, Kirscher, Sylvie, Laguerre, Brigitte, Fourme, Emmanuelle, Luneau, Sylvia, Genève, Jean, Debled, Marc

“…Abstract Rationale Breast cancer is a disease of ageing. Functional independence in elderly patients, measured with the Katz activities of daily living (ADL)…”
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Actionability of HER2-amplified circulating tumor cells in HER2-negative metastatic breast cancer: the CirCe T-DM1 trial by Jacot, William, Cottu, Paul, Berger, Frederique, Dubot, Coraline, Venat-Bouvet, Laurence, Lortholary, Alain, Bourgeois, Hugues, Bollet, Marc, Servent, Veronique, Luporsi, Elisabeth, Espié, Marc, Guiu, Severine, D'Hondt, Veronique, Dieras, Veronique, Sablin, Marie-Paule, Brain, Etienne, Neffati, Souhir, Pierga, Jean-Yves, Bidard, Francois-Clement

“…In this prospective phase 2 trial, we assessed the efficacy of trastuzumab-emtansine (T-DM1) in HER2-negative metastatic breast cancer (MBC) patients with…”
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Circulating Tumor Cell Detection Predicts Early Metastatic Relapse After Neoadjuvant Chemotherapy in Large Operable and Locally Advanced Breast Cancer in a Phase II Randomized Trial by Pierga, Jean-Yves, Bidard, François-Clément, Mathiot, Claire, Brain, Etienne, Delaloge, Suzette, Giachetti, Sylvie, de Cremoux, Patricia, Salmon, Rémy, Vincent-Salomon, Anne, Marty, Michel

“…Purpose: Circulating tumor cells in blood from metastatic breast cancer patients have been reported as a surrogate marker for tumor response and shorter…”
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A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer by Delorenzi, Mauro, Farmer, Pierre, Bonnefoi, Hervé, Anderle, Pascale, Cameron, David, Wirapati, Pratyakasha, Becette, Véronique, André, Sylvie, Piccart, Martine, Campone, Mario, Brain, Etienne, MacGrogan, Gaëtan, Petit, Thierry, Jassem, Jacek, Bibeau, Frédéric, Blot, Emmanuel, Bogaerts, Jan, Aguet, Michel, Bergh, Jonas, Iggo, Richard

“…Identifying factors that influence response to cancer chemotherapy is crucial for improving its efficacy. Mauro Delorenzi and his colleagues report that a…”
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Ki-67: level of evidence and methodological considerations for its role in the clinical management of breast cancer: analytical and critical review by Luporsi, Elisabeth, André, Fabrice, Spyratos, Frédérique, Martin, Pierre-Marie, Jacquemier, Jocelyne, Penault-Llorca, Frédérique, Tubiana-Mathieu, Nicole, Sigal-Zafrani, Brigitte, Arnould, Laurent, Gompel, Anne, Egele, Caroline, Poulet, Bruno, Clough, Krishna B., Crouet, Hubert, Fourquet, Alain, Lefranc, Jean-Pierre, Mathelin, Carole, Rouyer, Nicolas, Serin, Daniel, Spielmann, Marc, Haugh, Margaret, Chenard, Marie-Pierre, Brain, Etienne, de Cremoux, Patricia, Bellocq, Jean-Pierre

“…Clinicians can use biomarkers to guide therapeutic decisions in estrogen receptor positive (ER+) breast cancer. One such biomarker is cellular proliferation as…”
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