Search Results - "BRADY, Ciaran"

Transcriptomic analysis of IgG4 Fc‐fusion protein degradation in a panel of clonally‐derived CHO cell lines using RNASeq by Clarke, Colin, Gallagher, Clair, Kelly, Ronan M., Henry, Michael, Meleady, Paula, Frye, Christopher C., Osborne, Matthew D., Brady, Ciaran P, Barron, Niall, Clynes, Martin

“…In this study, we report an investigation of a panel of clonally‐derived Chinese hamster ovary (CHO) cell lines exhibiting variability in the proportion of…”
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Clonal variation in productivity and proteolytic clipping of an Fc-fusion protein in CHO cells: Proteomic analysis suggests a role for defective protein folding and the UPR by Henry, Michael, Gallagher, Clair, Kelly, Ronan M., Frye, Christopher C., Osborne, Matthew D., Brady, Ciaran P., Barron, Niall, Clynes, Martin, Meleady, Paula

“…•Proteomic analysis of CHO cells producing Fc-fusion protein with varying levels of product clipping is presented.•200 intracellular differentially expressed…”
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Capsaicin receptor TRPV1 in urothelium of neurogenic human bladders and effect of intravesical resiniferatoxin by Apostolidis, Apostolos, Brady, Ciaran M., Yiangou, Yiangos, Davis, John, Fowler, Clare J., Anand, Praveen

“…To study TRPV1 immunoreactivity in the urothelium of patients with neurogenic detrusor overactivity (NDO) before and after treatment with resiniferatoxin (RTX)…”
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Comparison of Intrarenal Pressures Generated by Irrigation Devices During Ureterorenoscopy in a Porcine Kidney Model by MacCraith, Eoin, Yap, Lee Chien, Elamin, Mutaz, Patterson, Kenneth, Brady, Ciaran, Hennessey, Derek

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Psychological distress in patients undergoing urological surgery: A single centre cross-sectional study by Murray, Nuala, O’Connor, Charles, Dempsey, Rhona, Ryan, Sean, Brady, Ciaran, Sweeney, Paul, Hennessey, Derek

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Post-Operative Opiate Use in Urological Patients: A Quality Improvement Study Aimed to Reduce the Risk of Opiate Dependence and Improve Safe Opiate Disposal Practices by O’Connor, Charles, Murray, Nuala, Dempsey, Rhona, Ryan, Sean, Brady, Ciaran, Sweeney, Paul, Hennessey, Derek

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P2X3-Immunoreactive Nerve Fibres in Neurogenic Detrusor Overactivity and the Effect of Intravesical Resiniferatoxin by Brady, Ciaran M, Apostolidis, Apostolos, Yiangou, Yiangos, Baecker, Preston A, Ford, Anthony P, Freeman, Alex, Jacques, Thomas S, Fowler, Clare J, Anand, Praveen

“…Objectives: The ATP-gated purinergic receptor P2X3 is expressed by small diameter sensory neurons and has been identified in normal and neurogenic human…”
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Delayed Ureteric Obstruction following Polytef STING procedure- Tip of an Iceberg or Blip on the Radar? by Elamin, Mutaz, Patterson, Ken, Yap, Lee Chien, McGuiness, Gerard, Abdella, Ashraf, Hennessey, Derek, Brady, Ciaran

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Efficacy of Commercialised Extracorporeal Shock Wave Lithotripsy Service: Comparing Outcomes Of 100 Consecutive Patients To International Outcomes by McGuinness, Gerard, Yap, Lee Chien, Elamin, Mutaz, Patterson, Kenneth, Brady, Ciaran, Sweeney, Paul, Hennessey, Derek

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Evaluation of Performance Parameters of the Disposable Flexible Ureterorenoscope (EU Scope) in Patients with Renal Stones: A Prospective, Observational, Single-arm, Study by Patterson, Kenneth, Yap, Lee Chien, Elamin, Mutaz, McGuinness, Gerard, Muheilan, Muheilan, Sharif, Ashraf, Darcy, Frank, Maccraith, Eoin, Brady, Ciaran, Sweeney, Paul, Hennessey, Derek

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Helminth vaccines: from mining genomic information for vaccine targets to systems used for protein expression by Dalton, John P, Brindley, Paul J, Knox, Dave P, Brady, Ciaran P, Hotez, Peter J, Donnelly, Sheila, O'Neill, Sandra M, Mulcahy, Grace, Loukas, Alex

“…The control of helminth diseases of people and livestock continues to rely on the widespread use of anti-helminthic drugs. However, concerns with the…”
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Maximum urethral closure pressure and sphincter volume in women with urinary retention by Wiseman, Oliver J, Swinn, Michael J, Brady, Ciaran M, Fowler, Clare J

“…In 1988 a syndrome of isolated urinary retention in young women that is associated with electromyographic abnormality of the striated urethral sphincter was…”
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The ultrastructure of bladder lamina propria nerves in healthy subjects and patients with detrusor hyperreflexia by Wiseman, Oliver J, Brady, Ciaran M, Hussain, Iqbal F, Dasgupta, Prokar, Watt, Hilary, Fowler, Clare J, Landon, David N

“…Detrusor hyperreflexia is a common finding in patients with neurological disease involving the spinal cord. In animal models it has been attributed to an…”
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High-Level Production of a Monoclonal Antibody in Murine Myeloma Cells by Perfusion Culture Using a Gravity Settler by Choo, Chiou-Yu, Tian, Yuan, Kim, Wan-Seop, Blatter, Erich, Conary, Jon, Brady, Ciaran P.

“…A perfusion system is described for the production of a human monoclonal antibody in non‐secreting murine myeloma (NS0) cells that was previously shown to be…”
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Keith Jeffery (1952–2016): an appreciation by Brady, Ciaran

“…* Department of History, Trinity College Dublin, cbrady@tcd.ie Keith John Jeffery: born 1952; educated Methodist College, Belfast, and St John’s College,…”
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‘Out of Scope’ – Operative Challenges in Ureteric Stone Management for Patient With Abnormal Ureteric Anatomy Post Multiple Urinary Diversion Procedures for Posterior Urethral Valves by Hayes, Leah, Brady, Ciaran, Hennessey, Derek

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MP06-05 ASSESSMENT OF INTRARENAL PRESSURES IN A PORCINE KIDNEY MODEL TO GUIDE EQUIPMENT SELECTION FOR RETROGRADE INTRARENAL SURGERY by MacCraith, Eoin, Yap, Lee, Elamin, Mutaz, Patterson, Kenneth, Brady, Ciaran, Hennessey, Derek

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GUT-ASSOCIATED IMMUNOLOCALIZATION OF THE SCHISTOSOMA MANSONI CYSTEINE PROTEASES, SmCL1 AND SmCL2 by Bogitsh, Burton J, Dalton, John P, Brady, Ciaran P, Brindley, Paul J

“…Transcripts encoding discrete, cathepsin L-like cysteine proteases, known as SmCL1 and SmCL2, have been reported from the adult stages of the human blood fluke…”
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The STING in the tale of Teflon®: Delayed ureteric obstruction after subureteric transurethral injection with polytetrafluoroethylene paste for vesicoureteral reflux by Murphy, Matthew, Scanlon, Lorraine, Elamin, Mutaz, O'Connor, Charles, Mayer, Nick, Brady, Ciaran, Hennessey, Derek

“…“Subureteric Teflon INGection” (STING) of polytetrafluoroethylene (PTFE/polytef) paste to treat vesicoureteral reflux (VUR) in children was popularised in…”
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Evolved care of neuropathic bladder from birth by Kath SHAVA, Brid CARR, Divyesh DESAI, Patrick DUFFY, Dominic THOMPSON and Ciaran BRADY

“…PURPOSE Management of patients with bladder dysfunction resulting from a primary diagnosis of spina bifida/spinal dysphraism remain a challenge. Our experience…”
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