Search Results - "BRADE, Helmut"

Critical Role for Interleukin-1β (IL-1β) during Chlamydia muridarum Genital Infection and Bacterial Replication-Independent Secretion of IL-1β in Mouse Macrophages by Prantner, Daniel, Darville, Toni, Sikes, James D, Andrews, Charles W. Jr, Brade, Helmut, Rank, Roger G, Nagarajan, Uma M

“…Recent findings have implicated interleukin-1β (IL-1β) as an important mediator of the inflammatory response in the female genital tract during chlamydial…”
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Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS by Gomery, Kathryn, Müller-Loennies, Sven, Brooks, Cory L., Brade, Lore, Kosma, Paul, Di Padova, Franco, Brade, Helmut, Evans, Stephen V.

“…Escherichia coli infections, a leading cause of septic shock, remain a major threat to human health because of the fatal action to endotoxin (LPS). Therapeutic…”
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Molecular and Structural Basis of Inner Core Lipopolysaccharide Alterations in Escherichia coli by Klein, Gracjana, Müller-Loennies, Sven, Lindner, Buko, Kobylak, Natalia, Brade, Helmut, Raina, Satish

“…It is well established that lipopolysaccharide (LPS) often carries nonstoichiometric substitutions in lipid A and in the inner core. In this work, the…”
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The lipopolysaccharide of the mastitis isolate Escherichia coli strain 1303 comprises a novel O-antigen and the rare K-12 core type by DUDA, Katarzyna A, LINDNER, Buko, BRADE, Helmut, LEIMBACH, Andreas, BRZUSZKIEWICZ, Elzbieta, DOBRINDT, Ulrich, HOIST, Otto

“…Mastitis represents one of the most significant health problems of dairy herds. The two major causative agents of this disease are Escherichia coli and…”
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Recognition of Heptoses and the Inner Core of Bacterial Lipopolysaccharides by Surfactant Protein D by Wang, Hua, Head, James, Kosma, Paul, Brade, Helmut, Müller-Loennies, Sven, Sheikh, Sharmin, McDonald, Barbara, Smith, Kelly, Cafarella, Tanya, Seaton, Barbara, Crouch, Erika

“…Lipopolysaccharides (LPS) of Gram-negative bacteria are important mediators of bacterial virulence that can elicit potent endotoxic effects. Surfactant protein…”
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Synthesis of a neoglycoconjugate containing a Chlamydophila psittaci-specific branched Kdo trisaccharide epitope by Kosma, Paul, Hofinger, Andreas, Müller-Loennies, Sven, Brade, Helmut

“…The chemical synthesis of a branched Kdo trisaccharide and its conjugation to BSA are described. The branched Kdo trisaccharide sodium (3-deoxy-α- d-…”
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Germline antibody recognition of distinct carbohydrate epitopes by Evans, Stephen V, Nguyen, Hoa P, Seto, Nina O L, MacKenzie, C Roger, Brade, Lore, Kosma, Paul, Brade, Helmut

“…High-resolution structures reveal how a germline antibody can recognize a range of clinically relevant carbohydrate epitopes. The germline response to a…”
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Cellular Recognition of Trimyristoylated Peptide or Enterobacterial Lipopolysaccharide via Both TLR2 and TLR4 by Spiller, Stephan, Dreher, Stefan, Meng, Guangxun, Grabiec, Alina, Thomas, Winston, Hartung, Thomas, Pfeffer, Klaus, Hochrein, Hubertus, Brade, Helmut, Bessler, Wolfgang, Wagner, Hermann, Kirschning, Carsten J.

“…Evidence for specific and direct bacterial product recognition through toll-like receptors (TLRs) has been emphasized recently. We analyzed lipopeptide…”
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Synthesis and antigenic properties of C-7-modified Kdo mono- and disaccharide ligands and Kdo disaccharide interresidue lactones by Sixta, Georg, Wimmer, Kurt, Hofinger, Andreas, Brade, Helmut, Kosma, Paul

“…In order to define binding interactions of Kdo-specific monoclonal antibodies directed against the chlamydial α-(2→8)-linked Kdo disaccharide epitope on a…”
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Escherichia coli K-12 Suppressor-free Mutants Lacking Early Glycosyltransferases and Late Acyltransferases by Klein, Gracjana, Lindner, Buko, Brabetz, Werner, Brade, Helmut, Raina, Satish

“…To elucidate the minimal lipopolysaccharide (LPS) structure needed for the viability of Escherichia coli, suppressor-free strains lacking either the…”
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Structural Analysis of Oligosaccharides from Lipopolysaccharide (LPS) of Escherichia coli K12 Strain W3100 Reveals a Link between Inner and Outer Core LPS Biosynthesis by Müller-Loennies, Sven, Lindner, Buko, Brade, Helmut

“…Lipopolysaccharide (LPS) from Escherichia coli K12 W3100 is known to contain several glycoforms, and the basic structure has been investigated previously by…”
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Bacterial endotoxin: molecular relationships of structure to activity and function by Rietschel, E T, Kirikae, T, Schade, F U, Mamat, U, Schmidt, G, Loppnow, H, Ulmer, A J, Zähringer, U, Seydel, U, Di Padova, F

“…Endotoxins of Gram-negative microbes fulfill as components of the outer membrane a vital function for bacterial viability and, if set free, induce in…”
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Sphingolipid metabolism during epidermal barrier development in mice by Doering, Thomas, Brade, Helmut, Sandhoff, Konrad

“…In rodents, a competent skin barrier to water loss is formed within 2 or 3 days prior to birth. Acquisition of barrier function during rat gestation correlates…”
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A lethal role for lipid A in Salmonella infections by Khan, Shahid A., Everest, Paul, Servos, Spiros, Foxwell, Neale, Zähringer, Ulrich, Brade, Helmut, Rietschel, Ernst Th, Dougan, Gordon, Charles, Ian G., Maskell, Duncan J.

“…Salmonella infections in naturally susceptible mice grow rapidly, with death occurring only after bacterial numbers in vivo have reached a high threshold…”
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A Novel 40-kDa Protein Containing Six Repeats of an Epidermal Growth Factor-Like Domain Functions as a Pattern Recognition Protein for Lipopolysaccharide by Ju, Jin Sung, Cho, Mi Hyang, Brade, Lore, Kim, Jung Hyun, Park, Ji Won, Ha, Nam-Chul, Soderhall, Irene, Soderhall, Kenneth, Brade, Helmut, Lee, Bok Luel

“…Determination of structures and functions of pattern recognition proteins are important for understanding pathogen recognition mechanisms in host defense and…”
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OpsX from Haemophilus influenzae Represents a Novel Type of Heptosyltransferase I in Lipopolysaccharide Biosynthesis by GRONOW, Sabine, BRABETZ, Werner, LINDNER, Buko, BRADE, Helmut

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Construction of a Deep-rough Mutant of Burkholderia cepacia ATCC 25416 and Characterization of Its Chemical and Biological Properties by Gronow, Sabine, Noah, Christian, Blumenthal, Antje, Lindner, Buko, Brade, Helmut

“…Burkholderia cepacia is a bacterium with increasing importance as a pathogen in patients with cystic fibrosis. The deep-rough mutant Ko2b was generated from B…”
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Identification of a Cross-reactive Epitope Widely Present in Lipopolysaccharide from Enterobacteria and Recognized by the Cross-protective Monoclonal Antibody WN1 222-5 by Müller-Loennies, Sven, Brade, Lore, MacKenzie, C.Roger, Di Padova, Franco E., Brade, Helmut

“…Septic shock due to infections with Gram-negative bacteria is a severe disease with a high mortality rate. We report the identification of the antigenic…”
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Hemoglobin enhances the biological activity of synthetic and natural bacterial (endotoxic) virulence factors: a general principle by Howe, Jörg, Richter, Walter, Hawkins, Lynn, Rössle, Manfred, Alexander, Christian, Fournier, Karin, Mach, Jean Pierre, Waelli, Thierry, Gorczynski, Reginald M, Ulmer, Artur J, Brade, Helmut, Zamyatina, Alla, Kosma, Paul, Rietschel, Ernst Th, Brandenburg, Klaus

“…Although hemoglobin (Hb) is mainly present in the cytoplasm of erythrocytes (red blood cells), lower concentrations of pure, cell-free Hb are released…”
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Structural analysis of deacylated lipopolysaccharide of Escherichia coli strains 2513 (R4 core‐type) and F653 (R3 core‐type) by Müller‐Loennies, Sven, Lindner, Buko, Brade, Helmut

“…Lipopolysaccharide (LPS) of Escherichia coli strain 2513 (R4 core‐type) yielded after alkaline deacylation one major oligosaccharide by high‐performance…”
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