Search Results - "BRACH, M. A"
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Prolongation of Survival of Human Polymorphonuclear Neutrophils by Granulocyte-Macrophage Colony-Stimulating Factor Is Caused By Inhibition of Programmed Cell Death
Published in Blood (01-12-1992)“…In the absence of appropriate stimuli, polymorphonuclear neutrophils (PMN) undergo programmed cell death (PCD), also termed apoptosis. We show that…”
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2
Ionizing radiation induces expression of interleukin 6 by human fibroblasts involving activation of nuclear factor-kappa B
Published in The Journal of biological chemistry (25-04-1993)“…We here report that human lung fibroblasts respond to x-ray treatment (XRT) with release of interleukin (IL)-6. Synthesis of IL-6 upon ionizing radiation is…”
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3
The role of tyrosine kinases and their substrates in signal transmission of hematopoietic growth factors: a short review
Published in Leukemia (01-05-1995)“…Both structure-function analysis of hematopoietic growth factor receptors and identification of novel signal transduction molecules have provided new insights…”
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4
Interleukin-4 Inhibits Growth of Multiple Myelomas by Suppressing Interleukin-6 Expression
Published in Blood (15-10-1991)“…Unfractionated bone marrow (BM) cells obtained form patients with multiple myeloma (MM) exhibit high levels of interleukin (IL)-6. Secretion of IL-6 by these…”
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5
Clinical applications of ribozymes
Published in The Lancet (British edition) (22-04-1995)Get more information
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6
The mitogenic response to tumor necrosis factor alpha requires c-Jun/AP-1
Published in Molecular and Cellular Biology (01-07-1993)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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7
Ribozymes : biology, biochemistry, and implications for clinical medicine
Published in Journal of molecular medicine (Berlin, Germany) (01-02-1995)“…Ribozymes are a class of ribonucleic acid (RNA) molecules that possess enzymatic properties. Upon binding to complementary nucleic acid strands, catalytic…”
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8
Transcriptional activation of the macrophage colony-stimulating factor gene by IL-2 is associated with secretion of bioactive macrophage colony-stimulating factor protein by monocytes and involves activation of the transcription factor NF-kappa B
Published in The Journal of immunology (1950) (15-06-1993)“…Human peripheral blood monocytes (Mo) constitutively display the beta-chain of the receptor for IL-2, whereas expression of the IL-2R alpha-chain is not…”
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Human fibroblasts express functional IL-2 receptors formed by the IL-2R alpha- and beta-chain subunits: association of IL-2 binding with secretion of the monocyte chemoattractant protein-1
Published in The Journal of immunology (1950) (15-07-1996)“…Expression of IL-2R was examined on human fibroblasts isolated from different tissues. By specific binding assay it is shown that [125I]IL-2 bound to…”
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10
Scapegoat for fraud in Germany?
Published in Nature (London) (02-04-1998)Get full text
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11
Effect of antiinflammatory agents on synthesis of MCP-1/JE transcripts by human blood monocytes
Published in Molecular pharmacology (01-07-1992)“…The human monocyte chemoattractant protein (MCP)-1 encoded by the JE gene belongs to a family of low molecular weight secretory cytokines with…”
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12
Activation of the transcription factor kappa B in human KG-1 myeloid leukemia cells treated with 1-beta-D-arabinofuranosylcytosine
Published in Molecular pharmacology (01-01-1992)“…The present studies have examined the effects of 1-beta-D-arabinofuranosylcytosine (ara-C) on activation of the transcription factor kappa B (NF-kappa B). The…”
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13
Interleukin-6 (IL-6) Is an Intermediate in IL-1–Induced Proliferation of Leukemic Human Megakaryoblasts
Published in Blood (15-11-1990)“…We have examined the in vitro effects of recombinant human (rh) interleukin-1 (IL-1) on the growth of purified megakaryoblasts obtained from patients with…”
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14
Expression of cytokine genes, cytokine receptor genes, and transcription factors in cultured hodgkin and Reed-Sternberg cells
Published in Cancer research (Chicago, Ill.) (15-06-1992)“…In the present study, we show by Northern blot analysis and enzyme linked immunosorbent assay that the Hodgkin's disease (HD)-derived cell lines HDLM-2 and…”
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15
High concentrations of the interleukin-1 receptor antagonist in serum of patients with Hodgkin's disease
Published in The Lancet (British edition) (17-10-1992)Get more information
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16
Identification of NF‐jun, a novel inducible transcription factor that regulates c‐jun gene transcription
Published in The EMBO journal (01-04-1992)“…In this study we report the identification of a novel transcription factor, termed Nuclear Factor‐jun (NF‐jun). This factor contributes to inducible…”
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17
Interleukin 9 is expressed by primary and cultured hodgkin and reed-sternberg cells
Published in Cancer research (Chicago, Ill.) (15-02-1992)“…We show by mRNA hybridization analysis and immunostaining using a mouse monoclonal antibody (moAb) to recombinant human interleukin 9 (IL-9) that both primary…”
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18
Activation of the AP-1 Transcription Factor by Arabinofuranosylcytosine in Myeloid Leukemia Cells
Published in Blood (01-02-1992)“…Previous studies have shown that 1-β-D-arabinofuranosylcy-tosine (ara-C) induces transcription of the c-jun immediate early response gene in human myeloid…”
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19
Serum levels of circulating ICAM-1 are increased in Hodgkin's disease
Published in Leukemia (01-08-1993)“…The intercellular adhesion molecule 1 (ICAM-1) is the ligand for the lymphocyte function-associated antigen 1 (LFA-1). The ICAM-1/LFA-1 complex mediates…”
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20
Interferon-gamma interrupts autocrine growth mediated by endogenous interleukin-6 in renal-cell carcinoma
Published in International journal of cancer (11-11-1991)“…Cells of the renal-cell carcinoma line ACHN constitutively produce IL-6, express the IL-6 receptor and use IL-6 in an autocrine fashion to augment their…”
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