Search Results - "BOZZA, Fernando"

Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19 by Hottz, Eugenio D., Azevedo-Quintanilha, Isaclaudia G., Palhinha, Lohanna, Teixeira, Lívia, Barreto, Ester A., Pão, Camila R.R., Righy, Cassia, Franco, Sérgio, Souza, Thiago M.L., Kurtz, Pedro, Bozza, Fernando A., Bozza, Patrícia T.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emergent pathogen responsible for the coronavirus disease 2019 (COVID-19). Since its…”
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Neuroanatomy of sepsis-associated encephalopathy by Heming, Nicholas, Mazeraud, Aurelien, Verdonk, Franck, Bozza, Fernando A, Chrétien, Fabrice, Sharshar, Tarek

“…This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2017. Other selected articles can be found online…”
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Characterisation of the first 250 000 hospital admissions for COVID-19 in Brazil: a retrospective analysis of nationwide data by Ranzani, Otavio T, Bastos, Leonardo S L, Gelli, João Gabriel M, Marchesi, Janaina F, Baião, Fernanda, Hamacher, Silvio, Bozza, Fernando A

“…Most low-income and middle-income countries (LMICs) have little or no data integrated into a national surveillance system to identify characteristics or…”
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Long-Term Quality of Life Among Survivors of Severe Sepsis: Analyses of Two International Trials by Yende, Sachin, Austin, Shamly, Rhodes, Andrew, Finfer, Simon, Opal, Steven, Thompson, Taylor, Bozza, Fernando A., LaRosa, Steven P., Ranieri, V. Marco, Angus, Derek C.

“…OBJECTIVES:To describe the quality of life among sepsis survivors. DESIGN:Secondary analyses of two international, randomized clinical trials (A Controlled…”
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Platelet proteome reveals novel pathways of platelet activation and platelet-mediated immunoregulation in dengue by Trugilho, Monique Ramos de Oliveira, Hottz, Eugenio Damaceno, Brunoro, Giselle Villa Flor, Teixeira-Ferreira, André, Carvalho, Paulo Costa, Salazar, Gustavo Adolfo, Zimmerman, Guy A, Bozza, Fernando A, Bozza, Patrícia T, Perales, Jonas

“…Dengue is the most prevalent human arbovirus disease worldwide. Dengue virus (DENV) infection causes syndromes varying from self-limiting febrile illness to…”
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Association Between Anxiety and New Organ Failure, Independently of Critical Illness Severity and Respiratory Status: A Prospective Multicentric Cohort Study by Mazeraud, Aurélien, Polito, Andrea, Sivanandamoorthy, Sivanthiny, Porcher, Raphaël, Heming, Nicholas, Stoclin, Annabelle, Hissem, Tarik, Antona, Marion, Blot, François, Gaillard, Raphaël, Chrétien, Fabrice, Annane, Djillali, Bozza, Fernando A. B., Siami, Shidasp, Sharshar, Tarek

“…OBJECTIVES:Anxiety results from the anticipation of a threat and might be associated with poor outcome in the critically ill. This study aims at showing that…”
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Neuroinflammation in Sepsis: Molecular Pathways of Microglia Activation by Moraes, Carolina, Zaverucha-do-Valle, Camila, Fleurance, Renaud, Sharshar, Tarek, Bozza, Fernando, d’Avila, Joana

“…Frequently underestimated, encephalopathy or delirium are common neurological manifestations associated with sepsis. Brain dysfunction occurs in up to 80% of…”
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Neuro-Inflammatory Response and Brain-Peripheral Crosstalk in Sepsis and Stroke by Bourhy, Lena, Mazeraud, Aurélien, Bozza, Fernando A, Turc, Guillaume, Lledo, Pierre-Marie, Sharshar, Tarek

“…Despite recent therapeutic advances, ischemic stroke is still a leading cause of death and disability. There is renewed attention on peripheral inflammatory…”
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Human megakaryocytes possess intrinsic antiviral immunity through regulated induction of IFITM3 by Campbell, Robert A., Schwertz, Hansjorg, Hottz, Eugenio D., Rowley, Jesse W., Manne, Bhanu Kanth, Washington, A. Valance, Hunter-Mellado, Robert, Tolley, Neal D., Christensen, Miles, Eustes, Alicia S., Montenont, Emilie, Bhatlekar, Seema, Ventrone, Cassandra H., Kirkpatrick, Beth D., Pierce, Kristen K., Whitehead, Stephen S., Diehl, Sean A., Bray, Paul F., Zimmerman, Guy A., Kosaka, Yasuhiro, Bozza, Patricia T., Bozza, Fernando A., Weyrich, Andrew S., Rondina, Matthew T.

“…Evolving evidence indicates that platelets and megakaryocytes (MKs) have unexpected activities in inflammation and infection; whether viral infections…”
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A multinational Delphi consensus to end the COVID-19 public health threat by Lazarus, Jeffrey V., Romero, Diana, Kopka, Christopher J., Karim, Salim Abdool, Abu-Raddad, Laith J., Almeida, Gisele, Baptista-Leite, Ricardo, Barocas, Joshua A., Barreto, Mauricio L., Bar-Yam, Yaneer, Bassat, Quique, Batista, Carolina, Bazilian, Morgan, Chiou, Shu-Ti, del Rio, Carlos, Dore, Gregory J., Gao, George F., Gostin, Lawrence O., Hellard, Margaret, Jimenez, Jose L., Kang, Gagandeep, Lee, Nancy, Matičič, Mojca, McKee, Martin, Nsanzimana, Sabin, Oliu-Barton, Miquel, Pradelski, Bary, Pyzik, Oksana, Rabin, Kenneth, Raina, Sunil, Rashid, Sabina Faiz, Rathe, Magdalena, Saenz, Rocio, Singh, Sudhvir, Trock-Hempler, Malene, Villapol, Sonia, Yap, Peiling, Binagwaho, Agnes, Kamarulzaman, Adeeba, El-Mohandes, Ayman

“…Despite notable scientific and medical advances, broader political, socioeconomic and behavioural factors continue to undercut the response to the COVID-19…”
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Platelets mediate increased endothelium permeability in dengue through NLRP3-inflammasome activation by Hottz, Eugenio D., Lopes, Juliana F., Freitas, Carla, Valls-de-Souza, Rogério, Oliveira, Marcus F., Bozza, Marcelo T., Da Poian, Andrea T., Weyrich, Andrew S., Zimmerman, Guy A., Bozza, Fernando A., Bozza, Patricia T.

“…Dengue is the most frequent hemorrhagic viral disease and re-emergent infection in the world. Although thrombocytopenia is characteristically observed in mild…”
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Vaccine effectiveness of ChAdOx1 nCoV-19 against COVID-19 in a socially vulnerable community in Rio de Janeiro, Brazil: author's response by Ranzani, Otavio T., Bozza, Fernando A.

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Platelets in Immune Response to Virus and Immunopathology of Viral Infections by Hottz, Eugenio D, Bozza, Fernando A, Bozza, Patrícia T

“…Platelets are essential effector cells in hemostasis. Aside from their role in coagulation, platelets are now recognized as major inflammatory cells with key…”
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Evolving changes in mortality of 13,301 critically ill adult patients with COVID-19 over 8 months by Kurtz, Pedro, Bastos, Leonardo S. L., Dantas, Leila F., Zampieri, Fernando G., Soares, Marcio, Hamacher, Silvio, Salluh, Jorge I. F., Bozza, Fernando A.

“…Purpose Clinical characteristics and management of COVID-19 patients have evolved during the pandemic, potentially changing their outcomes. We analyzed the…”
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Public hospitalizations for stroke in Brazil from 2009 to 2016 by Dantas, Leila F, Marchesi, Janaina F, Peres, Igor T, Hamacher, Silvio, Bozza, Fernando A, Quintano Neira, Ricardo A

“…Stroke is the third major cause of death in the world and the second in Brazil. The purpose of this work was to assess the stroke-related hospitalization,…”
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Using data envelopment analysis to perform benchmarking in intensive care units by Antunes, Bianca B P, Bastos, Leonardo S L, Hamacher, Silvio, Bozza, Fernando A

“…Studies using Data Envelopment Analysis to benchmark Intensive Care Units (ICUs) are scarce. Previous studies have focused on comparing efficiency using only…”
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SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes by Ferreira, André C., Soares, Vinicius Cardoso, de Azevedo-Quintanilha, Isaclaudia G., Dias, Suelen da Silva Gomes, Fintelman-Rodrigues, Natalia, Sacramento, Carolina Q., Mattos, Mayara, de Freitas, Caroline S., Temerozo, Jairo R., Teixeira, Lívia, Damaceno Hottz, Eugenio, Barreto, Ester A., Pão, Camila R. R., Palhinha, Lohanna, Miranda, Milene, Bou-Habib, Dumith Chequer, Bozza, Fernando A., Bozza, Patrícia T., Souza, Thiago Moreno L.

“…Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been associated with leukopenia and uncontrolled inflammatory response in…”
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Silencing of amygdala circuits during sepsis prevents the development of anxiety-related behaviours by Bourhy, Lena, Mazeraud, Aurélien, Costa, Luis H A, Levy, Jarod, Rei, Damien, Hecquet, Estéban, Gabanyi, Ilana, Bozza, Fernando A, Chrétien, Fabrice, Lledo, Pierre-Marie, Sharshar, Tarek, Lepousez, Gabriel

“…Sepsis is a life-threatening condition induced by a deregulated host response to severe infection. Post-sepsis syndrome includes long-term psychiatric…”
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Sepsis-associated Encephalopathy Is Septic by Mazeraud, Aurélien, Bozza, Fernando A, Sharshar, Tarek

“…[...]the current results indicate that pathogens have crossed the blood-brain barrier (BBB). [...]irrespective of their localization, it would be interesting…”
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App-based symptom tracking to optimize SARS-CoV-2 testing strategy using machine learning by Dantas, Leila F, Peres, Igor T, Bastos, Leonardo S L, Marchesi, Janaina F, de Souza, Guilherme F G, Gelli, João Gabriel M, Baião, Fernanda A, Maçaira, Paula, Hamacher, Silvio, Bozza, Fernando A

“…Tests are scarce resources, especially in low and middle-income countries, and the optimization of testing programs during a pandemic is critical for the…”
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