Search Results - "BOYER, Olivier"

Dermatomyositis and Immune-Mediated Necrotizing Myopathies: A Window on Autoimmunity and Cancer by Aussy, Audrey, Boyer, Olivier, Cordel, Nadège

“…Autoimmune myopathies (myositides) are strongly associated with malignancy. The link between myositis and cancer, originally noticed by Bohan and Peter in…”
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239th ENMC International Workshop: Classification of dermatomyositis, Amsterdam, the Netherlands, 14–16 December 2018 by Mammen, Andrew L., Allenbach, Yves, Stenzel, Werner, Benveniste, Olivier, Allenbach, Yves, Benveniste, Olivier, Bleecker, Jan De, Boyer, Olivier, Casciola-Rosen, Livia, Christopher-Stine, Lisa, Damoiseaux, Jan, Gitiaux, Cyril, Fujimoto, Manabu, Lamb, Janine, Landon-Cardinal, Océane, E. Lundberg, Ingrid, Mammen, Andrew, Nishino, Ichizo, Radke, Josefine, Selva-O'Callaghan, Albert, Stenzel, Werner, Vencovsky, Jiri, de Visser, Marianne, Wang, Guochun, Wedderburn, Lucy, Werth, Victoria

“…•Dermatomyositis-specific autoantibodies define unique clinical phenotypes.•Standardized autoantibody detection methods are needed.•Patients with…”
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Myositis-specific autoantibodies, a cornerstone in immune-mediated necrotizing myopathy by Anquetil, Céline, Boyer, Olivier, Wesner, Nadège, Benveniste, Olivier, Allenbach, Yves

“…Over the past few years, myositis-specific autoantibodies played an increasing role in the inflammatory idiopathic myositis definition. They became the…”
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Pathogenic role of anti–signal recognition protein and anti–3‐Hydroxy‐3‐methylglutaryl‐CoA reductase antibodies in necrotizing myopathies: Myofiber atrophy and impairment of muscle regeneration in necrotizing autoimmune myopathies by Arouche‐Delaperche, Louiza, Allenbach, Yves, Amelin, Damien, Preusse, Corinna, Mouly, Vincent, Mauhin, Wladimir, Tchoupou, Gaelle Dzangue, Drouot, Laurent, Boyer, Olivier, Stenzel, Werner, Butler‐Browne, Gillian, Benveniste, Olivier

“…Objective Immune‐mediated necrotizing myopathies (IMNM) may be associated with either anti–signal recognition protein (SRP) or…”
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High risk of cancer in autoimmune necrotizing myopathies: usefulness of myositis specific antibody by Allenbach, Yves, Keraen, Jeremy, Bouvier, Anne-Marie, Jooste, Valérie, Champtiaux, Nicolas, Hervier, Baptiste, Schoindre, Yoland, Rigolet, Aude, Gilardin, Laurent, Musset, Lucile, Charuel, Jean-Luc, Boyer, Olivier, Jouen, Fabienne, Drouot, Laurent, Martinet, Jeremie, Stojkovic, Tanya, Eymard, Bruno, Laforêt, Pascal, Behin, Antony, Salort-Campana, Emmanuelle, Fain, Olivier, Meyer, Alain, Schleinitz, Nicolas, Mariampillai, Kuberaka, Grados, Aurelie, Benveniste, Olivier

“…Cancer can occur in patients with inflammatory myopathies. This association is mainly observed in dermatomyositis, and myositis-specific antibodies have…”
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CD11c + B Cells Are Mainly Memory Cells, Precursors of Antibody Secreting Cells in Healthy Donors by Golinski, Marie-Laure, Demeules, Mélanie, Derambure, Céline, Riou, Gaetan, Maho-Vaillant, Maud, Boyer, Olivier, Joly, Pascal, Calbo, Sébastien

“…CD11c B cells have been reported to be increased in autoimmune diseases, but they are detected in the blood of healthy individuals as well. We aimed to…”
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HLA-Class II Artificial Antigen Presenting Cells in CD4 + T Cell-Based Immunotherapy by Couture, Alexandre, Garnier, Anthony, Docagne, Fabian, Boyer, Olivier, Vivien, Denis, Le-Mauff, Brigitte, Latouche, Jean-Baptiste, Toutirais, Olivier

“…CD4 T cells differentiate into various T helper subsets characterized by distinct cytokine secreting profiles that confer them effector functions adapted to a…”
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Efficacy of Rituximab in Refractory Inflammatory Myopathies Associated with Anti- Synthetase Auto-Antibodies: An Open-Label, Phase II Trial by Allenbach, Yves, Guiguet, Marguerite, Rigolet, Aude, Marie, Isabelle, Hachulla, Eric, Drouot, Laurent, Jouen, Fabienne, Jacquot, Serge, Mariampillai, Kuberaka, Musset, Lucile, Grenier, Philippe, Devilliers, Herve, Hij, Adrian, Boyer, Olivier, Herson, Serge, Benveniste, Olivier

“…Anti-synthetase syndrome (anti-SS) is frequently associated with myositis and interstitial lung disease (ILD). We evaluated prospectively, in a multicenter,…”
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Amyloid deposits and inflammatory infiltrates in sporadic inclusion body myositis: the inflammatory egg comes before the degenerative chicken by Benveniste, Olivier, Stenzel, Werner, Hilton-Jones, David, Sandri, Marco, Boyer, Olivier, van Engelen, Baziel G. M.

“…Sporadic inclusion body myositis (sIBM) is the most frequently acquired myopathy in patients over 50 years of age. It is imperative that neurologists and…”
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Influence of Pre-existing Anti-capsid Neutralizing and Binding Antibodies on AAV Vector Transduction by Fitzpatrick, Zachary, Leborgne, Christian, Barbon, Elena, Masat, Elisa, Ronzitti, Giuseppe, van Wittenberghe, Laetitia, Vignaud, Alban, Collaud, Fanny, Charles, Séverine, Simon Sola, Marcelo, Jouen, Fabienne, Boyer, Olivier, Mingozzi, Federico

“…Pre-existing immunity to adeno-associated virus (AAV) is highly prevalent in humans and can profoundly impact transduction efficiency. Despite the relevance to…”
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Glucocorticoids paradoxically promote steroid resistance in B cell acute lymphoblastic leukemia through CXCR4/PLC signaling by Abdoul-Azize, Souleymane, Hami, Rihab, Riou, Gaetan, Derambure, Céline, Charbonnier, Camille, Vannier, Jean-Pierre, Guzman, Monica L., Schneider, Pascale, Boyer, Olivier

“…Glucocorticoid (GC) resistance in childhood relapsed B-cell acute lymphoblastic leukemia (B-ALL) represents an important challenge. Despite decades of clinical…”
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Genetic and pharmacological inactivation of the purinergic P2RX7 receptor dampens inflammation but increases tumor incidence in a mouse model of colitis-associated cancer by Hofman, Paul, Cherfils-Vicini, Julien, Bazin, Marie, Ilie, Marius, Juhel, Thierry, Hébuterne, Xavier, Gilson, Eric, Schmid-Alliana, Annie, Boyer, Olivier, Adriouch, Sahil, Vouret-Craviari, Valérie

“…Colitis-associated cancer (CAC) is a complication of inflammatory bowel disease (IBD). Binding of extracellular ATP to the purinergic receptor P2RX7 has…”
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Pyroptotic and Necroptotic Cell Death in the Tumor Microenvironment and Their Potential to Stimulate Anti-Tumor Immune Responses by Scarpitta, Allan, Hacker, Ulrich T., Büning, Hildegard, Boyer, Olivier, Adriouch, Sahil

“…Cancer remains the second most common cause of death worldwide affecting around 10 million patients every year. Among the therapeutic options, chemotherapeutic…”
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IFNγ causes mitochondrial dysfunction and oxidative stress in myositis by Abad, Catalina, Pinal-Fernandez, Iago, Guillou, Clement, Bourdenet, Gwladys, Drouot, Laurent, Cosette, Pascal, Giannini, Margherita, Debrut, Lea, Jean, Laetitia, Bernard, Sophie, Genty, Damien, Zoubairi, Rachid, Remy-Jouet, Isabelle, Geny, Bernard, Boitard, Christian, Mammen, Andrew, Meyer, Alain, Boyer, Olivier

“…Idiopathic inflammatory myopathies (IIMs) are severe autoimmune diseases with poorly understood pathogenesis and unmet medical needs. Here, we examine the role…”
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Radiation therapy improves CAR T cell activity in acute lymphoblastic leukemia by Sugita, Mayumi, Yamazaki, Takahiro, Alhomoud, Mohammad, Martinet, Jérémie, Latouche, Jean-Baptiste, Golden, Encouse, Boyer, Olivier, Van Besien, Koen, Formenti, Silvia C., Galluzzi, Lorenzo, Guzman, Monica L.

“…Autologous T cells engineered to express a chimeric antigen receptor (CAR) specific for CD19 are approved for the treatment of various CD19 + hematological…”
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Immune reactivity directed against the carbamylated fibrinogen α chain does not cross-react with citrullinated fibrinogen immunodominant peptides in patients with rheumatoid arthritis by Brevet, Pauline, Boyer, Olivier, Vittecoq, Olivier, Fréret, Manuel

“…Somatic hypermutations in clonal B cells specific to citrullinated antigens during affinity maturation modify the antibody paratope, making it polyreactive…”
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Necrosis in anti-SRP + and anti-HMGCR + myopathies by Allenbach, Yves, Arouche-Delaperche, Louiza, Preusse, Corinna, Radbruch, Helena, Butler-Browne, Gillian, Champtiaux, Nicolas, Mariampillai, Kuberaka, Rigolet, Aude, Hufnagl, Peter, Zerbe, Norman, Amelin, Damien, Maisonobe, Thierry, Louis-Leonard, Sarah, Duyckaerts, Charles, Eymard, Bruno, Goebel, Hans-Hilmar, Bergua, Cecile, Drouot, Laurent, Boyer, Olivier, Benveniste, Olivier, Stenzel, Werner

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Prevalence and long-term monitoring of humoral immunity against adeno-associated virus in Duchenne Muscular Dystrophy patients by Leborgne, Christian, Latournerie, Virginie, Boutin, Sylvie, Desgue, Diana, Quéré, Aliénor, Pignot, Elodie, Collaud, Fanny, Charles, Séverine, Simon Sola, Marcelo, Masat, Elisa, Jouen, Fabienne, Boyer, Olivier, Masurier, Carole, Mingozzi, Federico, Veron, Philippe

“…•Level of AAV-specific IgG and NAb are similar in DMD patients and healthy donors.•Older DMD patients presented significantly lower anti-AAV8 IgG4…”
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Hepatic expression of GAA results in enhanced enzyme bioavailability in mice and non-human primates by Costa-Verdera, Helena, Collaud, Fanny, Riling, Christopher R., Sellier, Pauline, Nordin, Jayme M. L., Preston, G. Michael, Cagin, Umut, Fabregue, Julien, Barral, Simon, Moya-Nilges, Maryse, Krijnse-Locker, Jacomina, van Wittenberghe, Laetitia, Daniele, Natalie, Gjata, Bernard, Cosette, Jeremie, Abad, Catalina, Simon-Sola, Marcelo, Charles, Severine, Li, Mathew, Crosariol, Marco, Antrilli, Tom, Quinn, William J., Gross, David A., Boyer, Olivier, Anguela, Xavier M., Armour, Sean M., Colella, Pasqualina, Ronzitti, Giuseppe, Mingozzi, Federico

“…Pompe disease (PD) is a severe neuromuscular disorder caused by deficiency of the lysosomal enzyme acid alpha-glucosidase (GAA). PD is currently treated with…”
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The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation by Green, Alexa S., Chapuis, Nicolas, Trovati Maciel, Thiago, Willems, Lise, Lambert, Mireille, Arnoult, Christophe, Boyer, Olivier, Bardet, Valerie, Park, Sophie, Foretz, Marc, Viollet, Benoit, Ifrah, Norbert, Dreyfus, François, Hermine, Olivier, Cruz Moura, Ivan, Lacombe, Catherine, Mayeux, Patrick, Bouscary, Didier, Tamburini, Jerome

“…Finding an effective treatment for acute myeloid leukemia (AML) remains a challenge, and all cellular processes that are deregulated in AML cells should be…”
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