Search Results - "BOYD, JOHN H."
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PCSK9 is a critical regulator of the innate immune response and septic shock outcome
Published in Science translational medicine (15-10-2014)“…A decrease in the activity of proprotein convertase subtilisin/kexin type 9 (PCSK9) increases the amount of low-density lipoprotein (LDL) receptors on liver…”
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2
Inflammation in Myocardial Diseases
Published in Circulation research (06-01-2012)“…Inflammatory processes underlie a broad spectrum of conditions that injure the heart muscle and cause both structural and functional deficits. In this article,…”
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3
Lipopolysaccharide Is Cleared from the Circulation by Hepatocytes via the Low Density Lipoprotein Receptor
Published in PloS one (12-05-2016)“…Sepsis is the leading cause of death in critically ill patients. While decreased Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) function improves…”
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4
The Theory of Bank Risk Taking and Competition Revisited
Published in The Journal of finance (New York) (01-06-2005)“…There is a large body of literature that concludes that-when confronted with increased competition-banks rationally choose more risky portfolios. We argue that…”
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5
Inhibition of Cholesteryl Ester Transfer Protein Preserves High-Density Lipoprotein Cholesterol and Improves Survival in Sepsis
Published in Circulation (New York, N.Y.) (02-03-2021)“…The high-density lipoprotein hypothesis of atherosclerosis has been challenged by clinical trials of cholesteryl ester transfer protein (CETP) inhibitors,…”
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6
Scores for sepsis detection and risk stratification - construction of a novel score using a statistical approach and validation of RETTS
Published in PloS one (20-02-2020)“…To allow early identification of patients at risk of sepsis in the emergency department (ED), a variety of risk stratification scores and/or triage systems are…”
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7
Acute Respiratory Distress Syndrome in Pregnant Women
Published in Obstetrics and gynecology (New York. 1953) (01-03-2017)“…OBJECTIVE:To estimate the rate of acute respiratory distress syndrome (ARDS) in pregnant patients as well as to investigate clinical conditions associated with…”
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8
Limited echocardiography–guided therapy in subacute shock is associated with change in management and improved outcomes
Published in Journal of critical care (01-10-2014)“…Abstract Purpose The purpose of the study was to compare the effect of limited echocardiography (LE)–guided therapy to standard management on 28-day mortality,…”
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9
Normal-range blood lactate concentration in septic shock is prognostic and predictive
Published in Shock (Augusta, Ga.) (01-07-2012)“…We hypothesized that lactate levels even within the normal range are prognostic and that low lactate levels predict a beneficial response to vasopressin…”
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S100A8 and S100A9 Mediate Endotoxin-Induced Cardiomyocyte Dysfunction via the Receptor for Advanced Glycation End Products
Published in Circulation research (23-05-2008)“…Cardiovascular dysfunction as a result of sepsis is the leading cause of death in the critically ill. Cardiomyocytes respond to infectious pathogens with a…”
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11
The Stock Market's Reaction to Unemployment News: Why Bad News Is Usually Good for Stocks
Published in The Journal of finance (New York) (01-04-2005)“…We find that on average, an announcement of rising unemployment is good news for stocks during economic expansions and bad news during economic contractions…”
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12
Toll-Like Receptor 4-Mediated Activation of p38 Mitogen-Activated Protein Kinase Is a Determinant of Respiratory Virus Entry and Tropism
Published in Journal of Virology (01-11-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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13
Barriers to the effective treatment of sepsis: antimicrobial agents, sepsis definitions, and host-directed therapies
Published in Annals of the New York Academy of Sciences (01-09-2014)“…Sepsis is a complex clinical syndrome involving both infection and a deleterious host immune response. Antimicrobial agents are key elements of sepsis…”
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14
An Endotoxin Tolerance Signature Predicts Sepsis and Organ Dysfunction at Initial Clinical Presentation
Published in EBioMedicine (01-11-2014)“…Sepsis involves aberrant immune responses to infection, but the exact nature of this immune dysfunction remains poorly defined. Bacterial endotoxins like…”
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15
Extracellular Heat Shock Protein 70 Induces Cardiomyocyte Inflammation and Contractile Dysfunction via TLR2
Published in Circulation Journal (2011)“…Background: Toll-like receptors (TLRs) are expressed on cardiomyocytes and recognize pathogen-associated molecular patterns. Whether endogenous molecules…”
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16
Upper Airway Muscle Inflammation and Denervation Changes in Obstructive Sleep Apnea
Published in American journal of respiratory and critical care medicine (01-09-2004)“…Inflammatory cell infiltration and afferent neuropathy have been shown in the upper airway (UA) mucosa of subjects with obstructive sleep apnea (OSA). We…”
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17
The Understanding and Management of Organism Toxicity in Septic Shock
Published in Journal of innate immunity (01-01-2018)“…The toxicity caused by different organisms in septic shock is substantially complex and characterized by an intricate pathogenicity that involves several…”
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Survival benefit of a low ratio of visceral to subcutaneous adipose tissue depends on LDL clearance versus production in sepsis
Published in Critical care (London, England) (06-03-2018)“…Patients with sepsis with a high ratio of visceral adipose tissue (VAT) to subcutaneous adipose tissue (SAT) have increased mortality. Our goal was to…”
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Impact of the COVID-19 pandemic on non-COVID-19 community-acquired pneumonia: a retrospective cohort study
Published in BMJ open respiratory research (21-10-2023)“…BackgroundThe COVID-19 pandemic could impact frequency and mortality of non-COVID-19 community-acquired pneumonia (CAP). Changes in frequency, patient mix,…”
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20
The impact of inflation on financial sector performance
Published in Journal of monetary economics (01-04-2001)“…A growing theoretical literature describes mechanisms whereby even predictable increases in the rate of inflation interfere with the ability of the financial…”
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