Search Results - "BOYCE, Michael"
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The Arabidopsis O-fucosyltransferase SPINDLY activates nuclear growth repressor DELLA
Published in Nature chemical biology (01-05-2017)“…Mass spectrometry analysis combined with in vitro assays reveals that SPINDLY is an O -fucosyltransferase that modifies the growth repressor DELLA and…”
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Metabolic cross-talk allows labeling of O-linked β-N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway
Published in Proceedings of the National Academy of Sciences - PNAS (22-02-2011)“…Hundreds of mammalian nuclear and cytoplasmic proteins are reversibly glycosylated by O-linked β-N-acetylglucosamine (O-GlcNAc) to regulate their function,…”
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Glycosylation of KEAP1 links nutrient sensing to redox stress signaling
Published in The EMBO journal (01-08-2017)“…O‐GlcNAcylation is an essential, nutrient‐sensitive post‐translational modification, but its biochemical and phenotypic effects remain incompletely understood…”
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Educational and personal impacts of the COVID-19 pandemic on emergency medicine resident physicians: a qualitative study
Published in BMC medical education (27-09-2024)“…The COVID-19 pandemic had a significant impact on both the clinical practice and the psychological states of frontline physicians in the emergency department…”
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O-GlcNAcylation regulates neurofilament-light assembly and function and is perturbed by Charcot-Marie-Tooth disease mutations
Published in Nature communications (17-10-2023)“…The neurofilament (NF) cytoskeleton is critical for neuronal morphology and function. In particular, the neurofilament-light (NF-L) subunit is required for NF…”
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Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners
Published in Proceedings of the National Academy of Sciences - PNAS (27-03-2012)“…O-linked β-N-acetylglucosamine (O-GlcNAc) is a reversible posttranslational modification found on hundreds of nuclear and cytoplasmic proteins in higher…”
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Site-specific glycosylation regulates the form and function of the intermediate filament cytoskeleton
Published in eLife (07-03-2018)“…Intermediate filaments (IF) are a major component of the metazoan cytoskeleton and are essential for normal cell morphology, motility, and signal transduction…”
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Preparing for tenure at a research-intensive university
Published in BMC proceedings (22-06-2021)“…At research-intensive universities in the United States, eligible faculty must generally excel in research, teaching and service in order to receive tenure. To…”
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Use of an augmented reality sand table for satellite remote sensing education
Published in Journal of geography in higher education (08-08-2023)“…This experiment utilized advanced visualization technology for the delivery of an introductory remote sensing lesson in an undergraduate geography course…”
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Human UDP-galactose 4′-epimerase (GALE) is required for cell-surface glycome structure and function
Published in The Journal of biological chemistry (31-01-2020)“…Glycan biosynthesis relies on nucleotide sugars (NSs), abundant metabolites that serve as monosaccharide donors for glycosyltransferases. In vivo,…”
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Directing Traffic: Regulation of COPI Transport by Post-translational Modifications
Published in Frontiers in cell and developmental biology (11-09-2019)“…The coat protein complex I (COPI) is an essential, highly conserved pathway that traffics proteins and lipids between the endoplasmic reticulum (ER) and the…”
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Formative evaluation of an emergency department clinical decision support system for agitation symptoms: a study protocol
Published in BMJ open (19-02-2024)“…IntroductionThe burden of mental health-related visits to emergency departments (EDs) is growing, and agitation episodes are prevalent with such visits. Best…”
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13
Chemical Method for Labeling Lysine Methyltransferase Substrates
Published in Chembiochem : a European journal of chemical biology (24-01-2011)“…Several protein lysine methyltransferases (PKMTs) modify histones to regulate chromatin-dependent cellular processes, such as transcription, DNA replication…”
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14
B.A.D. (Black Abstraction Dreaming): A Conversation with Kevin Jerome Everson
Published in Black camera : the newsletter of the Black Film Center/Archives (01-10-2016)Get full text
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Export Control: Post-transcriptional Regulation of the COPII Trafficking Pathway
Published in Frontiers in cell and developmental biology (12-01-2021)“…The coat protein complex II (COPII) mediates forward trafficking of protein and lipid cargoes from the endoplasmic reticulum. COPII is an ancient and essential…”
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Design of instructions for evacuating disabled adults
Published in Applied ergonomics (01-01-2017)“…We investigated how the design of instructions can affect performance in preparing emergency stair travel devices for the evacuation of disable individuals. We…”
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Scientific Societies Advancing STEM Workforce Diversity: Lessons and Outcomes from the Minorities Affairs Committee of the American Society for Cell Biology
Published in Journal of microbiology & biology education (2020)“…Promoting diversity and inclusiveness in the STEM academic workforce remains a key challenge and national priority. Scientific societies can play a significant…”
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genome-wide RNAi screen reveals multiple regulators of caspase activation
Published in The Journal of cell biology (19-11-2007)“…Apoptosis is an evolutionally conserved cellular suicide mechanism that can be activated in response to a variety of stressful stimuli. Increasing evidence…”
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Cell surface glycoproteomic analysis of prostate cancer-derived PC-3 cells
Published in Bioorganic & medicinal chemistry letters (01-09-2011)“…Most clinically approved biomarkers of cancer are glycoproteins, and those residing on the cell surface are of particular interest in biotherapeutics. We…”
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A Novel Glycoproteomics Workflow Reveals Dynamic O-GlcNAcylation of COPγ1 as a Candidate Regulator of Protein Trafficking
Published in Frontiers in endocrinology (Lausanne) (15-10-2018)“…O-linked β-N-acetylglucosamine (O-GlcNAc) is an abundant and essential intracellular form of protein glycosylation in animals and plants. In humans,…”
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