Search Results - "BOYAKA, P. N"

Neutrophils negatively regulate induction of mucosal IgA responses after sublingual immunization by Jee, J, Bonnegarde-Bernard, A, Duverger, A, Iwakura, Y, Cormet-Boyaka, E, Martin, T L, Steiner, H E, Bachman, R C, Boyaka, P N

“…Induction of mucosal immunoglobulin-A (IgA) capable of providing a first line of defense against bacterial and viral pathogens remains a major goal of…”
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Medroxyprogesterone acetate and levonorgestrel increase genital mucosal permeability and enhance susceptibility to genital herpes simplex virus type 2 infection by Quispe Calla, N E, Vicetti Miguel, R D, Boyaka, P N, Hall-Stoodley, L, Kaur, B, Trout, W, Pavelko, S D, Cherpes, T L

“…Depot-medroxyprogesterone acetate (DMPA) is a hormonal contraceptive especially popular in areas with high prevalence of HIV and other sexually transmitted…”
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RANTES Potentiates Antigen-Specific Mucosal Immune Responses by Lillard, James W., Jr, Boyaka, Prosper N, Taub, Dennis D, McGhee, Jerry R

“…RANTES is produced by lymphoid and epithelial cells of the mucosa in response to various external stimuli and is chemotactic for lymphocytes. The role of…”
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Oral QS-21 Requires Early IL-4 Help for Induction of Mucosal and Systemic Immunity by Boyaka, Prosper N, Marinaro, Mariarosaria, Jackson, Raymond J, van Ginkel, Frederik W, Cormet-Boyaka, Estelle, Kirk, Kevin L, Kensil, Charlotte R, McGhee, Jerry R

“…The highly purified saponin derivative, QS-21, from the Quillaja saponaria Molina tree has been proved to be safe for parenteral administration and represents…”
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Aldehyde dehydrogenase-1a1 induces oncogene suppressor genes in B cell populations by Yasmeen, R., Meyers, J.M., Alvarez, C.E., Thomas, J.L., Bonnegarde-Bernard, A., Alder, H., Papenfuss, T.L., Benson, D.M., Boyaka, P.N., Ziouzenkova, O.

“…The deregulation of B cell differentiation has been shown to contribute to autoimmune disorders, hematological cancers, and aging. We provide evidence that the…”
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IKKβ in intestinal epithelial cells regulates allergen-specific IgA and allergic inflammation at distant mucosal sites by Bonnegarde-Bernard, A, Jee, J, Fial, M J, Aeffner, F, Cormet-Boyaka, E, Davis, I C, Lin, M, Tomé, D, Karin, M, Sun, Y, Boyaka, P N

“…Regulation of allergic responses by intestinal epithelial cells (IECs) remains poorly understood. Using a model of oral allergen sensitization in the presence…”
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Secretion of Sparfloxacin from the Human Intestinal Caco-2 Cell Line Is Altered by P-Glycoprotein Inhibitors by CORMET-BOYAKA, E, HUNEAU, J.-F, MORDRELLE, A, BOYAKA, P. N, CARBON, C, RUBINSTEIN, E, TOME, D

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Intraepithelial lymphocytes from villus tip and crypt portions of the murine small intestine show distinct characteristics by Kawabata, Shigetada, Boyaka, Prosper N., Coste, Michel, Fujihashi, Kohtaro, Yamamoto, Masafumi, McGhee, Jerry R., Kiyono, Hiroshi

“…Background & Aims: Intraepithelial lymphocytes (IELs) are located between epithelial cells that are thought to display unique features and functions at the…”
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Strategies for mucosal vaccine development by Boyaka, P N, Marinaro, M, Vancott, J L, Takahashi, I, Fujihashi, K, Yamamoto, M, van Ginkel, F W, Jackson, R J, Kiyono, H, McGhee, J R

“…Vaccines able to induce both secretory IgA for protection of mucosal surfaces and systemic immunity to pathogens invading the host are of great interest in the…”
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Effective Mucosal Immunity to Anthrax: Neutralizing Antibodies and Th Cell Responses Following Nasal Immunization with Protective Antigen by Boyaka, Prosper N, Tafaro, Angela, Fischer, Romy, Leppla, Stephen H, Fujihashi, Kohtaro, McGhee, Jerry R

“…Mucosal, but not parenteral, immunization induces immune responses in both systemic and secretory immune compartments. Thus, despite the reports that Abs to…”
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Salmonella-mediated mucosal cell-mediated immunity by Lillard, Jr, J W, Boyaka, P N, Singh, S, McGhee, J R

“…Oral immunization with the recombinant Salmonella typhimurium strain (BRD 847) expressing the C fragment of tetanus toxin (TT) induces brisk Ag-specific…”
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Mechanisms for Induction of Acquired Host Immunity by Neutrophil Peptide Defensins by Lillard, James W., Boyaka, Prosper N., Chertov, Oleg, Oppenheim, Joost J., McGhee, Jerry R.

“…Human neutrophil peptide (HNP) defensins were studied to determine their potential effects on adaptive mucosal immunity. Intranasal delivery of HNPs plus…”
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Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4 by Marinaro, M, Staats, HF, Hiroi, T, Jackson, RJ, Coste, M, Boyaka, PN, Okahashi, N, Yamamoto, M, Kiyono, H, Bluethmann, H

“…Despite pathophysiologic effects including diarrhea, cholera toxin (CT) is a potent mucosal immunogen and adjuvant. We investigated the influence of CT on T…”
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Human Nasopharyngeal-Associated Lymphoreticular Tissues : Functional Analysis of Subepithelial and Intraepithelial B and T Cells from Adenoids and Tonsils by Boyaka, Prosper N, Wright, Peter F, Marinaro, Mariarosaria, Kiyono, Hiroshi, Johnson, Joyce E, Gonzales, Ricardo A, Ikizler, Mine R, Werkhaven, Jay A, Jackson, Raymond J, Fujihashi, Kohtaro, Di Fabio, Simonetta, Staats, Herman F, McGhee, Jerry R

“…Subepithelial and intraepithelial lymphocytes of human adenoids and tonsils were characterized and directly compared to determine the potential contribution of…”
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IL-12 Is an Effective Adjuvant for Induction of Mucosal Immunity by Boyaka, Prosper N, Marinaro, Mariarosaria, Jackson, Raymond J, Menon, Satish, Kiyono, Hiroshi, Jirillo, Emilio, McGhee, Jerry R

“…We addressed the effects of two cytokines, IL-6 and IL-12, derived from APCs, for the development of mucosal IgA Ab responses following their nasal delivery…”
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Chimeras of Labile Toxin One and Cholera Toxin Retain Mucosal Adjuvanticity and Direct Th Cell Subsets Via Their B Subunit by Boyaka, Prosper N, Ohmura, Mari, Fujihashi, Kohtaro, Koga, Toshiya, Yamamoto, Masafumi, Kweon, Mi-Na, Takeda, Yoshifumi, Jackson, Raymond J, Kiyono, Hiroshi, Yuki, Yoshikazu, McGhee, Jerry R

“…Native cholera toxin (nCT) and the heat-labile toxin 1 (nLT) of enterotoxigenic Escherichia coli are AB5-type enterotoxins. Both nCT and nLT are effective…”
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Oral but not parenteral interleukin (IL)-12 redirects T helper 2 (Th2)-type responses to an oral vaccine without altering mucosal IgA responses by Marinaro, M, Boyaka, P N, Finkelman, F D, Kiyono, H, Jackson, R J, Jirillo, E, McGhee, J R

“…Our past studies have shown that the mucosal adjuvant cholera toxin (CT) induces T helper type 2 (Th2) responses with systemic IgG1, IgE and mucosal secretory…”
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Peanut-lupine antibody cross-reactivity is not associated to cross-allergenicity in peanut-sensitized mouse strains by Lifrani, Awatif, Dubarry, Michel, Rautureau, Michèle, Aattouri, Najat, Boyaka, Prosper N., Tomé, Daniel

“…Peanut hypersensitivity is one of the most common food allergies and one of the most common causes of death by food anaphylaxis in children and adults…”
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Use of Intranasal IL-12 to Target Predominantly Th1 Responses to Nasal and Th2 Responses to Oral Vaccines Given with Cholera Toxin by Marinaro, Mariarosaria, Boyaka, Prosper N, Jackson, Raymond J, Finkelman, Fred D, Kiyono, Hiroshi, Jirillo, Emilio, McGhee, Jerry R

“…We have investigated the effects of IL-12 and cholera toxin (CT) on the immune response to tetanus toxoid (TT) given by intranasal or oral routes. CT inhibited…”
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Syntaxin 1A is expressed in airway epithelial cells, where it modulates CFTR Cl(-) currents by Naren, A P, Di, A, Cormet-Boyaka, E, Boyaka, P N, McGhee, J R, Zhou, W, Akagawa, K, Fujiwara, T, Thome, U, Engelhardt, J F, Nelson, D J, Kirk, K L

“…The CFTR Cl(-) channel controls salt and water transport across epithelial tissues. Previously, we showed that CFTR-mediated Cl(-) currents in the Xenopus…”
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