Search Results - "BOWTON, David L"
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Diagnosis and treatment of ventilator-associated pneumonia
Published in Chest (01-08-2006)“…Ventilator-associated pneumonia (VAP) is the most common nosocomial infection in the ICU. Patients who acquire VAP have higher mortality rates and longer ICU…”
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Cuff Pressure Control: Are the Claims Inflated?
Published in Critical care medicine (01-10-2022)Get full text
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Ventilatory Management of the Noninjured Lung
Published in Clinics in chest medicine (01-12-2016)“…This article reviews aspects of mechanical ventilation in patients without lung injury, patients in the perioperative period, and those with neurologic injury…”
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Using local microbiologic data to develop institution-specific guidelines for the treatment of hospital-acquired pneumonia
Published in Chest (01-09-2006)“…While current guidelines recommend consideration of local microbiologic data when selecting empiric treatment for hospital-acquired pneumonia (HAP), few…”
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Predictors of successful extubation in neurosurgical patients
Published in American journal of respiratory and critical care medicine (01-03-2001)“…A respiratory therapist-driven weaning protocol incorporating daily screens, spontaneous breathing trials (SBT), and prompts to caregivers has been associated…”
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Effect on the Duration of Mechanical Ventilation of Identifying Patients Capable of Breathing Spontaneously
Published in The New England journal of medicine (19-12-1996)“…For over two decades, physicians have attempted to define the best methods of discontinuing mechanical ventilation in patients recovering from respiratory…”
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Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness
Published in The New England journal of medicine (27-12-2018)“…In a multicenter trial in 566 patients with critical illness who had delirium, the use of haloperidol or ziprasidone, as compared with placebo, had no…”
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Large scale implementation of a respiratory therapist-driven protocol for ventilator weaning
Published in American journal of respiratory and critical care medicine (01-02-1999)“…We prospectively investigated the large-scale implementation of a respiratory-therapist-driven protocol (TDP) that included 117 respiratory care practitioners…”
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Potential mucosal injury related to continuous aspiration of subglottic secretion device
Published in Anesthesiology (Philadelphia) (01-10-2007)Get full text
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Surfactant phospholipid changes after antigen challenge: a role for phosphatidylglycerol in dysfunction
Published in American journal of physiology. Lung cellular and molecular physiology (01-04-2005)“…In asthma, inflammation-mediated surfactant dysfunction contributes to increased airway resistance, but the mechanisms for dysfunction are not understood. To…”
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Nosocomial pneumonia risk and stress ulcer prophylaxis: a comparison of pantoprazole vs ranitidine in cardiothoracic surgery patients
Published in Chest (01-08-2009)“…Stress ulcer prophylaxis (SUP) using ranitidine, a histamine H2 receptor antagonist, has been associated with an increased risk of ventilator-associated…”
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Long-term outcomes after treatment of delirium during critical illness with antipsychotics (MIND-USA): a randomised, placebo-controlled, phase 3 trial
Published in The lancet respiratory medicine (01-08-2024)“…Delirium is common during critical illness and is associated with long-term cognitive impairment and disability. Antipsychotics are frequently used to treat…”
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Resolution of ventilator-associated pneumonia: Is my patient getting better?
Published in Critical care medicine (01-01-2010)Get full text
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The impact of hospital-wide use of a tapered-cuff endotracheal tube on the incidence of ventilator-associated pneumonia
Published in Respiratory care (01-10-2013)“…Aspiration of colonized oropharyngeal secretions is a major factor in the pathogenesis of ventilator-associated pneumonia (VAP). A tapered-cuff endotracheal…”
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Cell-Specific Expression of Group X and Group V Secretory Phospholipases A2 in Human Lung Airway Epithelial Cells
Published in American journal of respiratory cell and molecular biology (01-07-2000)“…Secretory phospholipase A(2) (sPLA(2)) enzymes contribute to inflammatory injury in human lungs by several mechanisms, including eicosanoid production and…”
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Education of physicians-in-training can decrease the risk for vascular catheter infection
Published in Annals of internal medicine (18-04-2000)“…Procedure instruction for physicians-in-training is usually nonstandardized. The authors observed that during insertion of central venous catheters (CVCs), few…”
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Regulation of Arachidonate Remodeling Enzymes Impacts Eosinophil Survival during Allergic Asthma
Published in American journal of respiratory cell and molecular biology (01-09-2009)“…Although the role of arachidonic acid (AA) metabolism to eicosanoids has been well established in allergy and asthma, recent studies in neoplastic cells have…”
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Variability in central venous pressure measurements and the potential impact on fluid management
Published in Shock (Augusta, Ga.) (01-03-2010)“…In the intensive care unit (ICU) of our tertiary care university medical center, central venous pressure (CVP) measurements derived from bedside monitors…”
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Delirium—The cost of inattention
Published in Critical care medicine (01-04-2004)Get full text
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Community-associated organisms in the intensive care unit—Dangerous or just passing through?
Published in Critical care medicine (01-07-2005)Get full text
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