Search Results - "BOWDON, B. J"
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Metabolism of carbovir, a potent inhibitor of human immunodeficiency virus type 1, and its effects on cellular metabolism
Published in Antimicrobial Agents and Chemotherapy (01-05-1993)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Safety factors involved in the extraction of biologically active proteins from human immunodeficiency virus
Published in Journal of virological methods (1998)“…The disruption of the viral coat of human immunodeficiency virus by Triton X-100, a nonionic detergent, is a time-dependent process which requires incubation…”
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3'-Azido-3'-deoxythymidine-induced reduction in the ability of uninfected CD4-expressing cells to participate in syncytium formation
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1992)“…A cocultivation assay system consisting of uninfected human T cells and cells chronically infected with human immunodeficiency virus type 1 has been used to…”
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Evaluation of anti-AIDS drugs in conventional mice implanted with a permeable membrane device containing human T cells infected with HIV
Published in Antiviral research (01-07-1997)“…We now report the confirmation of the work of Hollingshead et al. (1995) on development of a cell based hollow fiber (HF) system for evaluating potential…”
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A rational approach in the search for potent inhibitors against HIV proteinase
Published in The FASEB journal (01-08-1991)“…Synthetic peptides described as dog renin inhibitors were found to effectively inhibit the aspartyl protease of human immunodeficiency virus (HIV). The…”
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Biological and biochemical anti-HIV activity of the benzothiadiazine class of nonnucleoside reverse transcriptase inhibitors
Published in Antiviral research (01-09-1994)“…A series of benzothiadiazine derivatives were screened against the human immunodeficiency virus (HIV) and certain structure-activity relationships were defined…”
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Comparison of 1,2-dihydropyrido[3,4-b]pyrazines (1-deaza-7,8-dihydropteridines) with several other inhibitors of mitosis
Published in Cancer research (Chicago, Ill.) (15-03-1987)“…Several properties of four 1-deaza-7,8-dihydropteridines were compared with those of each other and with those of colchicine, nocodazole, podophyllotoxin, and…”
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Biological effects and structure-activity relationships of 1,2-dihydropyrido[3,4-b]pyrazines
Published in Cancer research (Chicago, Ill.) (01-08-1983)“…The effects of a number of 1,2-dihydropyrido[3,4-b]pyrazines (1-deaza-7,8-dihydropteridines) upon the proliferation and the mitotic index of cultured L1210…”
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DNA damage in cultured L1210 cells by 2-haloethyl esters of (methylsulfonyl)methanesulfonic acid
Published in Cancer research (Chicago, Ill.) (01-12-1986)“…The effects of the 2-chloroethyl, 2-bromoethyl, and 2-fluoroethyl esters of (methylsulfonyl)methanesulfonic acid upon the DNA of cultured L1210 cells have been…”
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Chemical properties and biological effects of 2-haloethyl sulfonates
Published in Biochemical pharmacology (01-10-1984)“…Data for the alkylating activities, DNA cross-linking activities, and proliferation-inhibitory activities toward cultured L1210 cells for twenty-four…”
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Identification of Analogues of Nicotinamide Adenine Dinucleotide among the Metabolites of 2,6-Diaminopurine in Mammalian Cells
Published in The Journal of biological chemistry (10-03-1966)“…Experimental evidence indicates that an analogue of nicotinamide adenine dinucleotide in which the adenine moiety is replaced by 2,6-diaminopurine is formed…”
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Interrelationships of some chemical, physicochemical, and biological activities of several 1-(2-haloethyl)-1-nitrosoureas
Published in Cancer research (Chicago, Ill.) (01-01-1974)Get full text
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Biological and biochemical effects of N-(2-chloroethyl)-N'-(trans-4-methylcyclohexyl)-N-nitrosourea on two transplantable murine colon tumors
Published in Cancer research (Chicago, Ill.) (01-12-1983)“…Other investigators have reported that transplantable murine colon Tumor 26 is more sensitive than transplantable colon Tumor 38 to treatment with…”
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Inhibition of mitosis and anticancer activity against experimental neoplasms by ethyl 5-amino-1,2-dihydro-3-[(N-methylanilino)methyl]-pyrido[3,4-b]pyrazin-7-ylcarbamate (NSC 181928)
Published in Cancer research (Chicago, Ill.) (01-03-1982)“…Ethyl 5-amino-1,2-dihydro-3-[N-methylanilino)methyl]pyrido[3,4-b]pyrazin-7-ylcarbamate (NSC 181928) is reported to be active against several experimental…”
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Comparison of the properties of metabolites of CCNU
Published in Biochemical pharmacology (15-12-1977)Get more information
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Comparison of the effects of cysteine upon the decomposition of nitrosoureas and of 1-methyl-3-nitro-1-nitrosoguanidine
Published in Biochemical pharmacology (15-01-1972)Get more information
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Effects of 1,3-bis(2-chloroethyl)-1-nitrosourea and related compounds upon the synthesis of DNA by cell-free systems
Published in Cancer research (Chicago, Ill.) (01-01-1968)Get full text
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Some effects of 1, 3-bis(2-chloroethyl)-1-nitrosourea upon the synthesis of protein and nucleic acids in vivo and in vitro
Published in Cancer research (Chicago, Ill.) (01-11-1965)Get full text
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Studies with 2,5-piperazinedione, 3,6-bis(5-chloro-2-piperidyl)-,dihydrochloride. I. Cell kinetic and biologic effects in cultured L1210, human epidermoid No. 2, and adenocarcinoma 755 cells
Published in Cancer treatment reports (01-09-1976)“…Experimental results obtained with cultured L1210, human epidermoid No. 2, and Adenocarcinoma 755 cells are consistent in showing that inhibition of…”
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