Search Results - "BOVENZI, V"
-
1
DNA methylation of retinoic acid receptor beta in breast cancer and possible therapeutic role of 5-aza-2'-deoxycytidine
Published in Anti-cancer drugs (01-06-1999)“…The retinoic acid receptor beta (RARbeta), a putative tumor suppressor gene, has been reported to be poorly expressed in breast cancer. In this report using…”
Get more information
Journal Article -
2
Valproate Induces Replication-independent Active DNA Demethylation
Published in The Journal of biological chemistry (25-07-2003)“…In this report, we demonstrate that valproic acid (VPA), a drug that has been used for decades in the treatment of epilepsy and as a mood stabilizer, triggers…”
Get full text
Journal Article -
3
Retroviral transfer and long-term expression of human cytidine deaminase cDNA in hematopoietic cells following transplantation in mice
Published in Gene therapy (01-11-1998)“…The chemotherapeutic effectiveness of cytosine nucleoside analogues used in cancer therapy is limited by their dose-dependent myelosuppression. A way to…”
Get full text
Journal Article -
4
DNA methylation and cancer
Published in Journal of cellular physiology (01-05-2000)“…The methylation of DNA is an epigenetic modification that can play an important role in the control of gene expression in mammalian cells. The enzyme involved…”
Get full text
Journal Article -
5
Responsiveness of Adenylate Cyclase to Pituitary Gonadotropins and Evidence of a Hormone-Induced Desensitization in the Lizard Ovary
Published in General and comparative endocrinology (01-07-1997)“…Gonadotropins (FSH and LH) affect several mammalian gonadal functions. In particular, FSH stimulates oogonial proliferation and oocyte growth, while LH…”
Get full text
Journal Article -
6
Antineoplastic action of 5-aza-2'-deoxycytidine and histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor β and estrogen receptor α genes in breast carcinoma cells
Published in Cancer chemotherapy and pharmacology (01-07-2001)“…During tumorigenesis several cancer-related genes can be silenced by aberrant methylation. In many cases these silenced genes can be reactivated by exposure to…”
Get full text
Journal Article -
7
Quantitation of Inhibition of DNA Methylation of the Retinoic Acid Receptor Gene by 5-Aza-2'-deoxycytidine in Tumor Cells Using a Single-Nucleotide Primer Extension Assay
Published in Analytical biochemistry (01-05-2000)“…The expression of several cancer-related genes has been reported to be silenced by DNA methylation of their promoter region. 5-Aza-2'-deoxycytidine…”
Get full text
Journal Article -
8
Antisense MBD2 gene therapy inhibits tumorigenesis
Published in The journal of gene medicine (01-07-2002)“…Background Aberration in the pattern of DNA methylation is one of the hallmarks of cancer. We present data suggesting that dysregulation of MBD2, a recently…”
Get full text
Journal Article -
9
Quantitation of Inhibition of DNA Methylation of the Retinoic Acid Receptor β Gene by 5-Aza-2′-deoxycytidine in Tumor Cells Using a Single-Nucleotide Primer Extension Assay
Published in Analytical biochemistry (15-05-2000)“…The expression of several cancer-related genes has been reported to be silenced by DNA methylation of their promoter region. 5-Aza-2′-deoxycytidine…”
Get full text
Journal Article -
10
Resistance to cytosine arabinoside by retrovirally mediated gene transfer of human cytidine deaminase into murine fibroblast and hematopoietic cells
Published in Cancer gene therapy (01-09-1996)“…Dose-limiting hematopoietic toxicity produced by the cytosine nucleoside analogue cytosine arabinoside (ARA-C) is one of the major factors that limit its use…”
Get more information
Journal Article