Search Results - "BOUW, Rene"

Zilucoplan in patients with acute hypoxic respiratory failure due to COVID-19 (ZILU-COV): A structured summary of a study protocol for a randomised controlled trial by Declercq, Jozefien, Bosteels, Cedric, Van Damme, Karel, De Leeuw, Elisabeth, Maes, Bastiaan, Vandecauter, Ans, Vermeersch, Stefanie, Delporte, Anja, Demeyere, Bénédicte, Vuylsteke, Marnik, Lalla, Marianna, Smart, Trevor, Detalle, Laurent, Bouw, René, Streffer, Johannes, Degeeter, Thibo, Vergotte, Marie, Guisez, Tanguy, Van Braeckel, Eva, Van Der Straeten, Catherine, Lambrecht, Bart N

“…Zilucoplan (complement C5 inhibitor) has profound effects on inhibiting acute lung injury post COVID-19, and can promote lung repair mechanisms that lead to…”
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Time‐dependent clearance of mycophenolic acid in renal transplant recipients by Van Hest, Reinier M., Van Gelder, Teun, Bouw, René, Goggin, Timothy, Gordon, Robert, Mamelok, Richard D., Mathot, Ron A.

“…Aims Pharmacokinetic studies of the immunosuppressive compound mycophenolic acid (MPA) have shown a structural decrease in clearance (CL) over time after renal…”
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Mycophenolic Acid Exposure after Administration of Mycophenolate Mofetil in the Presence and Absence of Ciclosporin in Renal Transplant Recipients by Kuypers, Dirk R., Ekberg, Henrik, Grinyó, Josep, Nashan, Björn, Vincenti, Flavio, Snell, Paul, Mamelok, Richard D., Bouw, Rene M.

“…Background and objective: The pharmacokinetics of mycophenolic acid (MPA) are complex, with large interindividual variability over time. There are also well…”
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Pharmacokinetics, efficacy, and safety of mycophenolate mofetil in combination with standard‐dose or reduced‐dose tacrolimus in liver transplant recipients by Nashan, Björn, Saliba, Faouzi, Durand, Francois, Barcéna, Rafael, Herrero, Jose Ignacio, Mentha, Gilles, Neuhaus, Peter, Bowles, Matthew, Patch, David, Bernardos, Angel, Klempnauer, Jürgen, Bouw, René, Ives, Jane, Mamelok, Richard, McKay, Diane, Truman, Matt, Marotta, Paul

“…The pharmacokinetics of mycophenolate mofetil (MMF) in liver transplant recipients may change because of pharmacokinetic interactions with coadministered…”
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Methodological aspects of the use of a calibrator in in vivo microdialysis-further development of the retrodialysis method by BOUW, M. R, HAMMARLUND-UDENAES, M

“…To investigate the performance of two alternative retrodialysis recovery methods and to describe the influence of different recoveries on the reliability in…”
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Clinical pharmacokinetic and pharmacodynamic profile of midazolam nasal spray by Bouw, M. René, Chung, Steve S., Gidal, Barry, King, Aliceson, Tomasovic, Jerry, Wheless, James W., Van Ess, Peter J.

“…•Nasally administered midazolam is rapidly, consistently, and extensively absorbed.•Alertness and psychomotor functionality return to baseline by ∼240 min post…”
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Concentrations of Gemifloxacin at the Target Site in Healthy Volunteers after a Single Oral Dose by ISLINGER, Florian, BOUW, Rene, STAHL, Mathias, LACKNER, Edith, ZELENY, Petra, BRUNNER, Martin, MÜLLER, Markus, EICHLER, Hans Georg, JOUKHADAR, Christian

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Phase I study assessing the safety, tolerability, and pharmacokinetics of avibactam and ceftazidime–avibactam in healthy Japanese volunteers by Tominaga, Nobumitsu, Edeki, Timi, Li, James, Learoyd, Maria, Bouw, M. René, Das, Shampa

“…Abstract Avibactam is a novel non-β-lactam β-lactamase inhibitor that has been shown to restore the in vitro activity of ceftazidime against pathogens…”
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Design of a patient‐ and investigator‐blind, randomized, placebo‐controlled study to evaluate efficacy, safety, and tolerability of bepranemab, UCB0107, in prodromal to mild Alzheimer’s disease: The TOGETHER Study, AH0003 by Barton, Matthew E, Byrnes, William, Mesa, Irene Rebollo, Bloemers, Jos, Maguire, Ralph Paul, Bouw, Rene, Tesseur, Ina, Ewen, Colin, Scheltens, Philip

“…Background Bepranemab is a recombinant, humanized, full‐length immunoglobulin G4 monoclonal antibody that binds to a central tau epitope (amino acids 235–250)…”
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Pharmacokinetic-pharmacodynamic modelling of morphine transport across the blood-brain barrier as a cause of the antinociceptive effect delay in rats: A microdialysis study by BOUW, M. René, GARDMARK, Marie, HAMMARLUND-UDENAES, Margareta

“…To quantify the contribution of distributional processes across the blood-brain barrier (BBB) to the delay in antinociceptive effect of morphine in rats…”
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Pharmacokinetics, safety, and efficacy of mycophenolate mofetil in combination with sirolimus or ciclosporin in renal transplant patients by Pescovitz, Mark D., Vincenti, Flavio, Hart, Marquis, Melton, Larry, Whelchel, John, Mulgaonkar, Shamkant, McKay, Diane, Leung, Mimi, Calleja, Elizabeth, Bouw, M. René

“…Aims To compare the pharmacokinetics of mycophenolic acid (MPA) and its metabolite (MPAG) when mycophenolate mofetil (MMF) is administered in combination with…”
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Safety and pharmacokinetics of daclizumab in pediatric renal transplant recipients by Pescovitz, Mark D., Knechtle, Stuart, Alexander, Steven R., Colombani, Paul, Nevins, Tom, Nieforth, Keith, Bouw, M. René

“…:  This study examined the safety and pharmacokinetics/pharmacodynamics of daclizumab in combination with mycophenolate mofetil (or azathioprine),…”
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Pharmacodynamics of oral ganciclovir and valganciclovir in solid organ transplant recipients by WILTSHIRE, Hugh, PAYA, Carlos V, ZUIDEVELD, Klaas P, PESCOVITZ, Mark D, HUMAR, Atul, DOMINGUEZ, Edward, WASHBURN, Kenneth, BLUMBERG, Emily, ALEXANDER, Barbara, FREEMAN, Richard, HEATON, Nigel

“…A randomized, double-blind study was conducted to evaluate the pharmacokinetics of ganciclovir following oral administration of ganciclovir or valganciclovir…”
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Pharmacokinetics of mycophenolate mofetil in stable pediatric liver transplant recipients receiving mycophenolate mofetil and cyclosporine by Lobritto, Steven J., Rosenthal, Philip, Bouw, Rene, Leung, Mimi, Snell, Paul, Mamelok, Richard D.

“…There are few pharmacokinetic data for mycophenolate mofetil (MMF) when used in combination with cyclosporine (CsA) in pediatric liver transplant recipients…”
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Development of a Predictive Limited Sampling Strategy for Estimation of Mycophenolic Acid Area Under the Concentration Time Curve in Patients Receiving Concomitant Sirolimus or Cyclosporine by FIGURSKI, Michal J, NAWROCKI, Artur, PESCOVITZ, Mark D, BOUW, Rene, SHAW, Leslie M

“…Limited sampling strategies for estimation of the area under the concentration time curve (AUC) for mycophenolic acid (MPA) co-administered with sirolimus…”
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Blood‐brain barrier transport and brain distribution of morphine‐6‐glucuronide in relation to the antinociceptive effect in rats – pharmacokinetic/pharmacodynamic modelling by Bouw, M René, Xie, Rujia, Tunblad, Karin, Hammarlund‐Udenaes, Margareta

“…The objective of this study was to investigate the contribution of the blood‐brain barrier (BBB) transport to the delay in antinociceptive effect of…”
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Mycophenolic acid exposure after administration of mycophenolate mofetil in the presence and absence of cyclosporin in renal transplant recipients by Kuypers, Dirk R, Ekberg, Henrik, Grinyó, Josep, Nashan, Björn, Vincenti, Flavio, Snell, Paul, Mamelok, Richard D, Bouw, Rene M

“…The pharmacokinetics of mycophenolic acid (MPA) are complex, with large interindividual variability over time. There are also well documented interactions with…”
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Modelling of the blood‐brain barrier transport of morphine‐3‐glucuronide studied using microdialysis in the rat: involvement of probenecid‐sensitive transport by Xie, Rujia, Bouw, M René, Hammarlund‐Udenaes, Margareta

“…The objective of this study was to investigate the impact of probenecid on the blood‐brain barrier (BBB) transport of morphine‐3‐glucuronide (M3G). Two groups…”
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Room C, 10/17/2000 9: 00 AM - 11: 00 AM (PS) Morphine Pharmacokinetics in Human Brain Varies with the Degree of Tissue Injury in Patients with Severe Brain Trauma by Ederoth, Per, Tunblad, Karin, Bouw, Rene, Lundberg, Johan, Nordstrom, Carl-Henrik

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Assessment of type I error rates for the statistical sub-model in NONMEM by WÄHLBY, Ulrika, BOUW, M. Rene, JONSSON, E. Niclas, KARLSSON, Mats O

“…The aim of this study was to assess the type I error rate when applying the likelihood ratio (LR) test, for components of the statistical sub-model in NONMEM…”
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