Search Results - "BOURBOULOUX, E"
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Prognostic impact of syndecan-1 expression in invasive ductal breast carcinomas
Published in British journal of cancer (17-06-2008)“…Carcinoma cells lack syndecan-1 expression when they are transiting from an epithelial to a less-differentiated mesenchymal phenotype (epithelial–mesenchymal…”
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Safety and pharmacokinetics of paclitaxel and the oral mTOR inhibitor everolimus in advanced solid tumours
Published in British journal of cancer (27-01-2009)“…Everolimus displays antiproliferative effects on cancer cells, yields antiangiogenic activity in established tumours, and shows synergistic activity with…”
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Evaluation of the safety of C-1311 (SYMADEX) administered in a phase 1 dose escalation trial as a weekly infusion for 3 consecutive weeks in patients with advanced solid tumours
Published in European journal of cancer (1990) (01-03-2010)“…Abstract Purpose C-1311 is a member of the novel imidazoacridinone family of anticancer agents. This phase 1 trial was designed to investigate the safety,…”
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Brown fat in breast cancer patients: analysis of serial (18)F-FDG PET/CT scans
Published in European journal of nuclear medicine and molecular imaging (01-07-2006)“…It has recently been suggested that FDG accumulation in the brown adipose tissue varies as a function of age, sex and outdoor temperature. The aim of this…”
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Vinflunine: a new active drug for second-line treatment of advanced breast cancer. Results of a phase II and pharmacokinetic study in patients progressing after first-line anthracycline taxane-based chemotherapy
Published in British journal of cancer (06-11-2006)“…To evaluate the single agent activity, pharmacokinetics and tolerability of the novel tubulin targeted agent vinflunine (VFL) (320 mg m(-2) q 21 days) as…”
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A phase I study of vinflunine in combination with capecitabine in patients with metastatic breast cancer previously treated with anthracyclines and taxanes
Published in Cancer chemotherapy and pharmacology (01-04-2012)“…Purpose A phase I study was performed to determine the maximal tolerated dose (MTD), recommended dose (RD), safety and efficacy of vinflunine when combined…”
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A rare gynecological case of paraneoplastic cerebellar degeneration discovered by FDG-PET
Published in Gynecologic oncology (01-05-2007)“…Abstract Background. PET/CT may be particularly useful to detect the primary cancer in paraneoplastic cerebellar degeneration (PCD) with anti-Yo which is most…”
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Lapatinib in metastatic breast cancer
Published in Women's health (London, England) (01-11-2009)“…Lapatinib is an oral, small-molecule, dual kinase inhibitor that targets both HER2 and the EGF receptor. Lapatinib was approved in June 2008 in Europe for the…”
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Phase i dose-escalation study of a novel antitumor agent, SR271425, administered intravenously in split doses (dl-d2-d3) in patients with refractory solid tumors
Published in Cancer chemotherapy and pharmacology (01-04-2007)“…SR271425 is a novel DNA-binding cytotoxic agent with a broad spectrum of antitumor activity in preclinical models,across a variety of the schedule of…”
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Brown fat in breast cancer patients: analysis of serial 18F-FDG PET/CT scans
Published in European journal of nuclear medicine and molecular imaging (01-07-2006)“…It has recently been suggested that FDG accumulation in the brown adipose tissue varies as a function of age, sex and outdoor temperature. The aim of this…”
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A personalized adjuvant treatment for women over 70 presenting with a luminal breast cancer? ASTER 70s or an ongoing phase III trial with parallel cohort by the UNICANCER GERICO and UCBG groups for an ongoing question
Published in Journal of geriatric oncology (01-10-2012)Get full text
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6 months versus 12 months of adjuvant trastuzumab in early breast cancer (PHARE): final analysis of a multicentre, open-label, phase 3 randomised trial
Published in The Lancet (British edition) (29-06-2019)“…In 2013, the interim analysis of the Protocol for Herceptin as Adjuvant therapy with Reduced Exposure (PHARE) trial could not show that 6 months of adjuvant…”
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Efficacy and Safety of First-line Single-Agent Carboplatin vs Carboplatin Plus Paclitaxel for Vulnerable Older Adult Women With Ovarian Cancer: A GINECO/GCIG Randomized Clinical Trial
Published in JAMA oncology (01-06-2021)“…Single-agent carboplatin is often proposed instead of a conventional carboplatin-paclitaxel doublet in vulnerable older patients with ovarian cancer. Such an…”
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