Search Results - "BOULOUX, P. M. G"

Modifying muscle mass – the endocrine perspective by Solomon, A M, Bouloux, P M G

“…This review describes the major hormonal factors that determine the balance between human skeletal muscle anabolism and catabolism in health and disease, with…”
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What is the optimal therapy for young males with hypogonadotropic hypogonadism? by Han, T. S., Bouloux, P. M. G.

“…Summary Hypogonadotropic hypogonadism (HH), consequent to congenital or acquired disorders of the hypothalamic–pituitary axis, presents as…”
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Nasally located ectopic ACTH-secreting pituitary adenoma (EAPA) causing Nelson’s syndrome: diagnostic challenges by Gurazada, K., Ihuoma, A., Galloway, M., Dorward, N., Wilhelm, T., Khoo, B., Bouloux, P. M. G.

“…Purpose We report the first case of an Ectopic adrenocorticotrophin (ACTH)-secreting pituitary adenoma (EAPA) located within the posterior nasal septum…”
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GnRH‐I and GnRH‐II have differential modulatory effects on human peripheral blood mononuclear cell proliferation and interleukin‐2 receptor γ‐chain mRNA expression in healthy males by Tanriverdi, F., Gonzalez‐Martinez, D., Hu, Y., Kelestimur, F., Bouloux, P. M. G.

“…Summary GnRH‐I and its receptor (GnRHR‐I) have previously been demonstrated and shown to be biologically active in the immune system, notably within peripheral…”
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Unilateral renal aplasia in X-linked Kallmann's syndrome by Kirk, J M, Grant, D B, Besser, G M, Shalet, S, Quinton, R, Smith, C S, White, M, Edwards, O, Bouloux, P M

“…Unilateral renal agenesis is an uncommon association with Kallmann's syndrome (KS) (hypogonadotrophic hypogonadism and olfactory defect). We have investigated…”
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The hypothalamic-pituitary-gonadal axis: immune function and autoimmunity by Tanriverdi, F, Silveira, LF, MacColl, GS, Bouloux, PM

“…GnRH and sex steroids play an important role in immune system modulation and development. GnRH and the GnRH receptor are produced locally by immune cells,…”
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Expression of gonadotropin-releasing hormone type-I (GnRH-I) and type-II (GnRH-II) in human peripheral blood mononuclear cells (PMBCs) and regulation of B-lymphoblastoid cell proliferation by GnRH-I and GnRH-II by Tanriverdi, F, Gonzalez-Martinez, D, Silveira, L F G, Hu, Y, Maccoll, G S, Travers, P, Bouloux, P M G

“…GnRH-I and its receptor (GnRHR-I) have previously been demonstrated and shown to be biologically active in the immune system, notably within T cells. Recently…”
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Deletion analysis maps ocular albinism proximal to the steroid sulphatase locus by Bouloux, P M, Kirk, J, Munroe, P, Duke, V, Meindl, A, Hilson, A, Grant, D, Carter, N, Betts, D, Meitinger, T

“…We describe a pedigree in which four male members are affected by a contiguous gene abnormality involving the short arm of the X chromosome (Xp22.32)…”
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Gonadal function and response to human chorionic and menopausal gonadotrophin therapy in male patients with idiopathic hypogonadotrophic hypogonadism by Kirk, J M, Savage, M O, Grant, D B, Bouloux, P M, Besser, G M

“…This study was designed to determine the response to therapy using human chorionic gonadotrophin (hCG) and human menopausal gonadotrophin (hMG) in males with…”
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Comparison of the clinical activity of mesulergine and pergolide in the treatment of hyperprolactinaemia by Grossman, A, Bouloux, P M, Loneragan, R, Rees, L H, Wass, J A, Besser, G M

“…The clinical activity of the new ergoline, mesulergine, was compared to pergolide in the treatment of hyperprolactinaemia. Mesulergine was given to 22 women…”
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Two cases of Wegener's granulomatosis involving the pituitary by Roberts, G A, Eren, E, Sinclair, H, Pelling, M, Burns, A, Bradford, R, Maurice-Williams, R, Black, C M, Finer, N, Bouloux, P M

“…We describe two patients with Wegener's granulomatosis involving the pituitary. The diagnosis of Wegener's granulomatosis was inferred from the histological…”
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Naloxone provokes catecholamine release in phaeochromocytomas and paragangliomas by Bouloux, P M, Grossman, A, Besser, G M

“…The effects of low- (2 mg) and high-dose (10 mg) intravenous naloxone administration on circulating plasma catecholamines in four patients with proven and two…”
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Evidence for the participation of endogenous opioids in the sympathoadrenal response to hypoglycaemia in man by Bouloux, P M, Grossman, A, Lytras, N, Besser, G M

“…The effects of the long acting met-enkephalin analogue D-Ala2-MePhe4-met-enkephalin-O-ol (DAMME) and the opiate antagonist naloxone on the plasma catecholamine…”
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Novel homozygous splice acceptor site GnRH receptor (GnRHR) mutation: Human GnRHR knockout by SILVEIRA, L. F. G, STEWART, P. M, THOMAS, M, CLARK, D. A, BOULOUX, P. M. G, MACCOLL, G. S

“…Mutations in the GnRH receptor (GnRHR) have been shown to be responsible for a significant number of autosomic recessive and, less commonly, sporadic cases of…”
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Genetic analysis of NR0B1 in congenital adrenal hypoplasia patients: identification of a rare regulatory variant resulting in congenital adrenal hypoplasia and hypogonadal hypogonadism without testicular carcinoma in situ by Walker, A P, Fowkes, R C, Saleh, F, Kim, S-H, Wilkinson, P, Cabrera-Sharp, V, Talmud, P J, Humphries, S E, Looijenga, L H J, Bouloux, P M G

“…There have been few testicular histology reports of adult patients with congenital adrenal hypoplasia/hypogonadal hypogonadism (AHC/HH), but Leydig cell…”
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Effects of dopamine and morphine on immunoreactive somatostatin and LH-releasing hormone secretion from hypothalamic fragments in vitro by Lengyel, A M, Grossman, A, Bouloux, P M, Rees, L H, Besser, G M

“…Dopamine and morphine modulate GH and LH release, probably at a hypothalamic locus. To investigate this in more detail, we studied the influence of these…”
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Kallmann's syndrome: is it always for life? by QUINTON, R, CHEOW, H. K, TYMMS, D. J, BOULOUX, P.-M. G, WU, F. C. W, JACOBS, H. S

“…OBJECTIVE Kallmann's syndrome (KS) is defined by the association of olfactory deficit with irreversible, congenital gonadotrophin deficiency (IHH). We present…”
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Identification of olfactory dysfunction in carriers of X-linked Kallmann's syndrome by Kirk, J M, Grant, D B, Savage, M O, Besser, G M, Bouloux, P M

“…The aim of the study was to test the hypothesis that clinically unaffected female carriers of X-linked Kallmann's syndrome have an olfactory defect. Assessment…”
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Sex and smell--an enigma resolved by Bouloux, P M, Munroe, P, Kirk, J, Besser, G M

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An in-situ isolated rat adrenal perfusion system for study of neurally mediated catecholamine secretion: effects of morphine, a Met-enkephalin analogue, and naloxone on catecholamine secretion by Bouloux, P M, Perrett, D, Sopwith, M, Besser, G M

“…An in-situ isolated rat adrenal perfusion technique has been devised to study the opioid control of neurally mediated adrenomedullary catecholamine release…”
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