Search Results - "BOULOUMIE, Anne"
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Unexpected trafficking of immune cells within the adipose tissue during the onset of obesity
Published in Biochemical and biophysical research communications (10-07-2009)“…The primary inflammatory events occurring in the adipose tissue (AT) during high fat diet (HFD)-induced obesity are poorly defined. The present study was…”
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Identification of adipose tissue dendritic cells correlated with obesity-associated insulin-resistance and inducing Th17 responses in mice and patients
Published in Diabetes (New York, N.Y.) (01-09-2012)“…T-cell regulation in adipose tissue provides a link between inflammation and insulin resistance. Because of alterations in adipose tissue T-cell composition in…”
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Interplay Between Human Adipocytes and T Lymphocytes in Obesity: CCL20 as an Adipochemokine and T Lymphocytes as Lipogenic Modulators
Published in Arteriosclerosis, thrombosis, and vascular biology (01-10-2009)“…OBJECTIVE—Adipose tissue (AT) plays a major role in the low-grade inflammatory state associated with obesity. The aim of the present study was to characterize…”
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Adipose Tissue Endothelial Cells From Obese Human Subjects: Differences Among Depots in Angiogenic, Metabolic, and Inflammatory Gene Expression and Cellular Senescence
Published in Diabetes (New York, N.Y.) (01-11-2010)“…Regional differences among adipose depots in capacities for fatty acid storage, susceptibility to hypoxia, and inflammation likely contribute to complications…”
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Metagenome and metabolism: the tissue microbiota hypothesis
Published in Diabetes, obesity & metabolism (01-09-2013)“…Over the last decade, the research community has revealed the role of a new organ: the intestinal microbiota. It is considered as a symbiont that is part of…”
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Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota
Published in Gut (01-04-2012)“…The gut microbiota, which is considered a causal factor in metabolic diseases as shown best in animals, is under the dual influence of the host genome and…”
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The visceral adipose tissue bacterial microbiota provides a signature of obesity based on inferred metagenomic functions
Published in International Journal of Obesity (01-10-2023)“…Background Metabolic inflammation mediated obesity requires bacterial molecules to trigger immune and adipose cells leading to inflammation and adipose depot…”
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Immune Cell Toll-like Receptor 4 Mediates the Development of Obesity- and Endotoxemia-Associated Adipose Tissue Fibrosis
Published in Cell reports (Cambridge) (22-05-2014)“…Adipose tissue fibrosis development blocks adipocyte hypertrophy and favors ectopic lipid accumulation. Here, we show that adipose tissue fibrosis is…”
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Divergent immunometabolic changes in adipose tissue and skeletal muscle with ageing in healthy humans
Published in The Journal of physiology (01-02-2022)“…Key points Ageing is associated with increased systemic inflammation and metabolic dysfunction that contributes to the development of age‐associated diseases…”
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CD36 Is a Marker of Human Adipocyte Progenitors with Pronounced Adipogenic and Triglyceride Accumulation Potential
Published in Stem cells (Dayton, Ohio) (01-07-2017)“…White adipose tissue (WAT) expands in part through adipogenesis, a process involving fat cell generation and fatty acid (FA) storage into triglycerides (TGs)…”
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The Impact of Long-term Physical Inactivity on Adipose Tissue Immunometabolism
Published in The journal of clinical endocrinology and metabolism (01-01-2022)“…Adipose tissue and physical inactivity both influence metabolic health and systemic inflammation, but how adipose tissue responds to chronic physical…”
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Periprostatic Adipose Tissue Displays a Chronic Hypoxic State that Limits Its Expandability
Published in The American journal of pathology (01-06-2022)“…White adipose tissue accumulates at various sites throughout the body, some adipose tissue depots exist near organs whose function they influence in a…”
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Endothelial DLL4 Is an Adipose Depot–Specific Fasting Sensor Regulating Fatty Acid Fluxes
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2023)“…Adaptation of fat depots to change in fuel availability is critical for metabolic flexibility and cardiometabolic health. The mechanisms responsible for fat…”
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TGFbeta family members are key mediators in the induction of myofibroblast phenotype of human adipose tissue progenitor cells by macrophages
Published in PloS one (15-02-2012)“…The present study was undertaken to characterize the remodeling phenotype of human adipose tissue (AT) macrophages (ATM) and to analyze their paracrine effects…”
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Human Multipotent Adipose‐Derived Stem Cells Differentiate into Functional Brown Adipocytes
Published in Stem cells (Dayton, Ohio) (01-11-2009)“…In contrast to the earlier contention, adult humans have been shown recently to possess active brown adipose tissue with a potential of being of metabolic…”
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Human White and Brite Adipogenesis is Supported by MSCA1 and is Impaired by Immune Cells
Published in Stem cells (Dayton, Ohio) (01-04-2015)“…Obesity‐associated inflammation contributes to the development of metabolic diseases. Although brite adipocytes have been shown to ameliorate metabolic…”
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Native Adipose Stromal Cells Egress from Adipose Tissue In Vivo: Evidence During Lymph Node Activation
Published in Stem cells (Dayton, Ohio) (01-07-2013)“…Adipose tissue (AT) has become accepted as a source of multipotent progenitor cells, the adipose stromal cells (ASCs). In this regard, considerable work has…”
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Leptin, the Product of Ob Gene, Promotes Angiogenesis
Published in Circulation research (16-11-1998)“…The adipocyte-derived cytokine leptin is thought to play a key role in the control of satiety and energy expenditure. Because adipogenesis and angiogenesis are…”
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Adipocytes Secrete Leukotrienes: Contribution to Obesity-Associated Inflammation and Insulin Resistance in Mice
Published in Diabetes (New York, N.Y.) (01-09-2012)“…Leukotrienes (LTs) are potent proinflammatory mediators, and many important aspects of innate and adaptive immune responses are regulated by LTs. Key members…”
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Chemotaxis and Differentiation of Human Adipose Tissue CD34+/CD31− Progenitor Cells: Role of Stromal Derived Factor‐1 Released by Adipose Tissue Capillary Endothelial Cells
Published in Stem cells (Dayton, Ohio) (01-09-2007)“…The native CD34+/CD31− cell population present in the stroma‐vascular fraction of human adipose tissue (hAT) displays progenitor cell properties since they…”
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