Search Results - "BOTTOMS, M. A"

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  1. 1

    Oxidative alterations in the experimental glycation model of diabetes mellitus are due to protein-glucose adduct oxidation : some fundamental differences in proposed mechanisms of glucose oxidation and oxidant production by HUNT, J. V, BOTTOMS, M. A, MITCHINSON, M. J

    Published in Biochemical journal (15-04-1993)
    “…Modification of human serum albumin (HSA) with formaldehyde resulted in a loss of 75% of available lysine residues, but there was no change in histidine…”
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    Journal Article
  2. 2

    Glucose oxidation and low-density lipoprotein-induced macrophage ceroid accumulation : possible implications for diabetic atherosclerosis by HUNT, J. V, BOTTOMS, M. A, CLARE, K, SKAMARAUSKAS, J. T, MITCHINSON, M. J

    Published in Biochemical journal (15-05-1994)
    “…The exposure of proteins to high concentrations of glucose in vitro is widely considered a relevant model of the functional degeneration of tissue occurring in…”
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  3. 3

    Differing effects of probucol and vitamin E on the oxidation of lipoproteins, ceroid accumulation and protein uptake by macrophages by Hunt, J V, Bottoms, M A, Taylor, S E, Lyell, V, Mitchinson, M J

    Published in Free radical research (01-01-1994)
    “…Studies using 125I-low density lipoprotein (125I-LDL) show that probucol (10 microM) and alpha-tocopherol (100 microM) inhibit protein degradation in LDL…”
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    Journal Article
  4. 4

    Ascorbic acid oxidation: A potential cause of the elevated severity of atherosclerosis in diabetes mellitus? by Hunt, James V., Bottoms, Mark A., Mitchinson, Malcolm J.

    Published in FEBS letters (19-10-1992)
    “…The exposure of mouse peritoneal macrophages to cholesterol linoleate-containing, artificial lipoproteins can lead to intracellular ceroid accumulation. This…”
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  5. 5

    Flow cytometric measurement of ceroid accumulation in macrophages by Hunt, J V, Carpenter, K L, Bottoms, M A, Carter, N P, Marchant, C E, Mitchinson, M J

    Published in Atherosclerosis (25-01-1993)
    “…Flow cytometry has been examined as a method for quantitative measurement of the accumulation in macrophages of ceroid, an autofluorescent polymer composed of…”
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  6. 6

    Measurement of ceroid accumulation in macrophages by flow cytometry by Hunt, J. V., Bottoms, M. A., Skamarauskas, J., Carter, N. P., Mitchinson, M. J.

    Published in Cytometry (New York, N.Y.) (01-04-1994)
    “…The accumulation in macrophages of ceroid, an sutofluorescent polymer composed of oxidised protein and lipid, can be monitored seiniquantitatively by staining…”
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  7. 7

    Lipid oxidation, lipoprotein cell-association and ceroid accumulation in P388D1 macrophage-like cells by Marchant, C E, Bottoms, M A, Law, N, Mitchinson, M J, Hunt, J V

    Published in Biochimica et biophysica acta (08-12-1994)
    “…Flow cytometry can be used to quantify the accumulation of ceroid in macrophages, the result of cellular handling of certain lipoproteins. Using P388D1 cells,…”
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    Journal Article
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