Search Results - "BOTTI, Joëlle"
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Novel function of PiT1/SLC20A1 in LPS-related inflammation and wound healing
Published in Scientific reports (12-02-2019)“…PiT1/SLC20A1 is an inorganic phosphate transporter with additional functions including the regulation of TNFα-induced apoptosis, erythropoiesis, cell…”
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Autophagy: A Druggable Process
Published in Annual review of pharmacology and toxicology (06-01-2017)“…Macroautophagy (hereafter called autophagy) is a vacuolar, lysosomal pathway for catabolism of intracellular material that is conserved among eukaryotic cells…”
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3
Fine-tuning autophagy: from transcriptional to posttranslational regulation
Published in American Journal of Physiology: Cell Physiology (01-09-2016)“…Macroautophagy (hereafter called autophagy) is a vacuolar lysosomal pathway for degradation of intracellular material in eukaryotic cells. Autophagy plays…”
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4
Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy
Published in Proceedings of the National Academy of Sciences - PNAS (16-02-2016)“…Autophagy is an essential component of innate immunity, enabling the detection and elimination of intracellular pathogens. Legionella pneumophila, an…”
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Regulation of Autophagy by Sphingosine Kinase 1 and Its Role in Cell Survival during Nutrient Starvation
Published in The Journal of biological chemistry (31-03-2006)“…The sphingolipid ceramide induces macroautophagy (here called autophagy) and cell death with autophagic features in cancer cells. Here we show that…”
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Autophagy Signaling and the Cogwheels of Cancer
Published in Autophagy (01-04-2006)“…The downregulation of macroautophagy observed in cancer cells is associated with tumor progression. The regulation of macroautophagy by signaling pathways…”
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7
A SNX1-SNX2-VAPB partnership regulates endosomal membrane rewiring in response to nutritional stress
Published in Life science alliance (01-03-2023)“…Nutrient deprivation ("starvation") is a major catabolic stress faced by mammalian cells in both pathological and physiological situations. Starvation induces…”
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The primary cilium protein folliculin is part of the autophagy signaling pathway to regulate epithelial cell size in response to fluid flow
Published in Cell Stress (25-02-2019)“…Autophagy is a conserved molecular pathway directly involved in the degradation and recycling of intracellular components. Autophagy is associated with a…”
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Monitoring lipophagy in kidney epithelial cells in response to shear stress
Published in Methods in cell biology (2021)Get full text
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10
Is Autophagy the Key Mechanism by Which the Sphingolipid Rheostat Controls the Cell Fate Decision?
Published in Autophagy (01-01-2007)“…Sphingolipids are major constituents of biological membrane and some of them behave as second messengers involved in the cell fate decision. Ceramide and…”
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11
Autophagy modulates cell migration and β1 integrin membrane recycling
Published in Cell cycle (Georgetown, Tex.) (15-10-2013)“…Cell migration is dependent on a series of integrated cellular events including the membrane recycling of the extracellular matrix receptor integrins. In this…”
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Regulation of autophagy by extracellular matrix glycoproteins in HeLa cells
Published in Autophagy (01-01-2011)“…Macroautophagy is a major lysosomal degradation pathway for cellular components in eukaryotic cells. Baseline macroautophagy is important for quality control…”
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13
Sphingolipids in macroautophagy
Published in Methods in molecular biology (Clifton, N.J.) (2008)“…Sphingolipids are constituents of biological membranes. Ceramide and sphingosine 1-phosphate (S1P) also act as second messengers and are part of a rheostat…”
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14
Evolving views in prion glycosylation: functional and pathological implications
Published in Biochimie (01-01-2003)“…Prion diseases form a group of neurodegenerative disorders with the unique feature of being transmissible. These diseases involve a pathogenic protein, called…”
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15
Modification of the N‐linked oligosaccharides in cell surface glycoproteins during chick embryo development
Published in European journal of biochemistry (01-06-1985)“…Important differences in asparagine‐linked glycopeptides were observed in in vitro cultured fibroblasts derived from chick embryo at different stages of…”
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Defect of N-glycosylation is not directly related to congenital disorder of glycosylation Ia fibroblast sensitivity to staurosporine-induced cell death
Published in Pediatric research (01-08-2005)“…Congenital disorder of glycosylation Ia (CDGIa) is an autosomal recessive disease that is caused by mutations in the gene PMM2 encoding phosphomannomutase, an…”
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Autophagy and cancer stem cells or tumor-initiating cells in human breast cancer
Published in Frontiers in pharmacology (2014)“…Abstract only…”
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18
Two laminin receptors with N -acetylglucosamine-binding specificity
Published in Biochimie (01-01-2003)“…Two glycoproteins, the first, CBP70 which has lectin properties, and the second, cbg72 which is a laminin-1 receptor, have been previously described. We…”
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Concanavalin A-induced impairment of fibroblast spreading on laminin but not on fibronectin
Published in Journal of cellular physiology (01-09-1988)“…The effect of concanavalin A (Con A) on the adhesion of 8-day-old chick embryo fibroblasts (CEFs) to fibronectin (FN) and laminin (LM) was studied. Con A was…”
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Modification of the N-linked oligosaccharides in cell surface glycoproteins during chick embryo development. A using lectin affinity and a high resolution chromatography study
Published in European journal of biochemistry (01-01-1985)“…Important differences in asparagine-linked glycopeptides were observed in vitro cultured fibroblasts derived from chick embryo at different stages of…”
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