Search Results - "BOTTI, G"

Immunoscore and Immunoprofiling in cancer: an update from the melanoma and immunotherapy bridge 2015 by Galon, J, Fox, B A, Bifulco, C B, Masucci, G, Rau, T, Botti, G, Marincola, F M, Ciliberto, G, Pages, F, Ascierto, P A, Capone, M

“…The fifth "Melanoma Bridge Meeting" took place in Naples, December 1-5th, 2015. The main topics discussed at this meeting were: Molecular and Immuno advances,…”
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Low doses of Bisphenol A have pro-inflammatory and pro-oxidant effects, stimulate lipid peroxidation and increase the cardiotoxicity of Doxorubicin in cardiomyoblasts by Quagliariello, V., Coppola, C., Mita, D.G., Piscopo, G., Iaffaioli, R.V., Botti, G., Maurea, N.

“…[Display omitted] •Bisphenol A increase the Doxorubicin-Induced cardiotoxicity.•Bisphenol A have pro-oxidative and pro-inflammatory effects in…”
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Clinical activity of FOLFIRI plus cetuximab according to extended gene mutation status by next-generation sequencing: findings from the CAPRI-GOIM trial by Ciardiello, F., Normanno, N., Maiello, E., Martinelli, E., Troiani, T., Pisconti, S., Giuliani, F., Barone, C., Cartenì, G., Rachiglio, A.M., Montesarchio, V., Tonini, G., Rizzi, D., Cinieri, S., Bordonaro, R., Febbraro, A., De Vita, F., Orditura, M., Fenizia, F., Lambiase, M., Rinaldi, A., Tatangelo, F., Botti, G., Colucci, G.

“…Treatment with antiepidermal growth factor receptor (anti-EGFR) monoclonal antibodies has been restricted to metastatic colorectal cancer (mCRC) patients with…”
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Cardiotoxicity and pro-inflammatory effects of the immune checkpoint inhibitor Pembrolizumab associated to Trastuzumab by Quagliariello, V., Passariello, M., Coppola, C., Rea, D., Barbieri, A., Scherillo, M., Monti, M.G., Iaffaioli, R.V., De Laurentiis, M., Ascierto, P.A., Botti, G., De Lorenzo, C., Maurea, N.

“…The immunotherapy has revolutionized the world of oncology in the last decades with considerable advantages in terms of overall survival in cancer patients…”
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Hydroxide-Induced Degradation of Olefin Metathesis Catalysts: A Challenge for Metathesis in Alkaline Media by Goudreault, Alexandre Y, Walden, Daniel M, Nascimento, Daniel L, Botti, Adrian G, Steinmann, Stephan N, Michel, Carine, Fogg, Deryn E

“…Hydroxide ion is shown to be a potent disruptor of Ru-catalyzed olefin metathesis, in a study of the Hoveyda catalyst HII. Addition of [N n Bu4]­[OH]…”
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Prospective Monitoring of Polyomavirus BK Replication and Impact of Pre‐Emptive Intervention in Pediatric Kidney Recipients by Ginevri, F., Azzi, A., Hirsch, H. H., Basso, S., Fontana, I., Cioni, M., Bodaghi, S., Salotti, V., Rinieri, A., Botti, G., Perfumo, F., Locatelli, F., Comoli, P.

“…Polyoma BK virus (BKV)‐associated nephropathy (PVAN) is a relevant cause of poor renal allograft survival. In a prospective analysis, we monitored BKV DNA in…”
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Heterogeneity of KRAS, NRAS, BRAF and PIK3CA mutations in metastatic colorectal cancer and potential effects on therapy in the CAPRI GOIM trial by Normanno, N., Rachiglio, A.M., Lambiase, M., Martinelli, E., Fenizia, F., Esposito, C., Roma, C., Troiani, T., Rizzi, D., Tatangelo, F., Botti, G., Maiello, E., Colucci, G., Ciardiello, F., Giuliani, F., Simone, G., Febbraro, A., Tommaselli, E., Cinieri, S., Criscuolo, M., Perrino, A., Rinaldi, A., Bordonaro, R., Manusia, M., Romito, S., Bufo, P., Cartenì, G., Biglietto, M., Nappi, O., Cardarelli, A., Montesarchio, E., Micheli, P., Nasti, G., Chicchinelli, N., Iannaccone, A., Russo, A., Cabibi, D., Giaccone, P., Barone, C., Rindi, G., Tonini, G., Onetti Muda, A., Perrone, G., Latiano, T., Graziano, P., Pisconti, S., Sebastio, A.

“…Evidence suggests that metastatic colorectal carcinoma (mCRC) has a high level of intratumor heterogeneity. We carried out a quantitative assessment of tumor…”
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The non-pathogenic Australian lagovirus RCV-A1 causes a prolonged infection and elicits partial cross-protection to rabbit haemorrhagic disease virus by Strive, T, Wright, J, Kovaliski, J, Botti, G, Capucci, L

“…Abstract Two caliciviruses occur in Australian wild rabbits: rabbit calicivirus Australia 1 (RCV-A1) and rabbit haemorrhagic disease virus (RHDV), which is…”
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Deregulation of HOX B13 expression in urinary bladder cancer progression by Marra, L, Cantile, M, Scognamiglio, G, Perdonà, S, La Mantia, E, Cerrone, M, Gigantino, V, Cillo, C, Caraglia, M, Pignata, S, Facchini, G, Botti, G, Chieffi, S, Chieffi, P, Franco, R

“…Urinary bladder cancer is a common malignancy in industrialized countries. More than 90% of bladder cancer originates in the transitional cells. Bladder…”
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CXCR4 and CXCR7 transduce through mTOR in human renal cancer cells by Ieranò, C, Santagata, S, Napolitano, M, Guardia, F, Grimaldi, A, Antignani, E, Botti, G, Consales, C, Riccio, A, Nanayakkara, M, Barone, M V, Caraglia, M, Scala, S

“…Treatment of metastatic renal cell carcinoma (mRCC) has improved significantly with the advent of agents targeting the mTOR pathway, such as temsirolimus and…”
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SARS-CoV-2 infection: NLRP3 inflammasome as plausible target to prevent cardiopulmonary complications? by Quagliariello, V, Bonelli, A, Caronna, A, Lombari, M C, Conforti, G, Libutti, M, Iaffaioli, R V, Berretta, M, Botti, G, Maurea, N

“…NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3) inflammasome has recently become an intriguing target of several chronic and viral diseases. Here, we…”
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BRAF and PIK3CA genes are somatically mutated in hepatocellular carcinoma among patients from South Italy by Colombino, M, Sperlongano, P, Izzo, F, Tatangelo, F, Botti, G, Lombardi, A, Accardo, M, Tarantino, L, Sordelli, I, Agresti, M, Abbruzzese, A, Caraglia, M, Palmieri, G

“…Poor data have been previously reported about the mutation rates in K-RAS , BRAF , and PIK3CA genes among patients with hepatocellular carcinoma (HCC). Here we…”
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Efficacy of two Ni-Ti systems and hand files for removing gutta-percha from root canals by Mollo, A., Botti, G., Prinicipi Goldoni, N., Randellini, E., Paragliola, R., Chazine, M., Ounsi, H. F., Grandini, S.

“…Mollo A, Botti G, Prinicipi Goldoni N, Randellini E, Paragliola R, Chazine M, Ounsi HF, Grandini S. Efficacy of two Ni‐Ti systems and hand files for removing…”
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Weekly docetaxel versus CMF as adjuvant chemotherapy for older women with early breast cancer: final results of the randomized phase III ELDA trial by Perrone, F., Nuzzo, F., Di Rella, F., Gravina, A., Iodice, G., Labonia, V., Landi, G., Pacilio, C., Rossi, E., De Laurentiis, M., D'Aiuto, M., Botti, G., Forestieri, V., Lauria, R., De Placido, S., Tinessa, V., Daniele, B., Gori, S., Colantuoni, G., Barni, S., Riccardi, F., De Maio, E., Montanino, A., Morabito, A., Daniele, G., Di Maio, M., Piccirillo, M.C., Signoriello, S., Gallo, C., de Matteis, A.

“…Evidence on adjuvant chemotherapy for elderly early breast cancer patients is poor, due to the low number of phase 3 trials. ELDA shows that weekly docetaxel…”
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The HOX genes network in uro-genital cancers: mechanisms and potential therapeutic implications by Cantile, M, Franco, R, Schiavo, G, Procino, A, Cindolo, L, Botti, G, Cillo, C

“…Genito-urinary malignancies (prostate, bladder, renal and testicular cancers) rank high among human tumors with an incidence that varies with age and organ…”
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Midface lift: our current approaches by Botti, G, Botti, C

“…In the last few years, surgery of the ageing face seems to have shifted from tissue uplifting and tightening to mere filling. We do not agree with this trend…”
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WNT pathway in oral cancer: Epigenetic inactivation of WNT-inhibitors by PANNONE, G, BUFO, P, CARAGLIA, M, PAPAGERAKIS, S, LO MUZIO, L, SANTORO, A, FRANCO, R, AQUINO, G, LONGO, F, BOTTI, G, SERPICO, R, CAFARELLI, B, ABBRUZZESE, A

“…Epigenetic DNA methylations plays an important role in oral carcinogenesis. The soluble frizzled receptor protein (SFRP) family together with WIF-1 and DKK-3…”
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Risk Differences Between Prediabetes And Diabetes According To Breast Cancer Molecular Subtypes by Crispo, A., Augustin, L.S.A., Grimaldi, M., Nocerino, F., Giudice, A., Cavalcanti, E., Di Bonito, M., Botti, G., De Laurentiis, M., Rinaldo, M., Esposito, E., Riccardi, G., Amore, A., Libra, M., Ciliberto, G., Jenkins, D.J.A., Montella, M.

“…Hyperglycemia and hyperinsulinemia may play a role in breast carcinogenesis and prediabetes and diabetes have been associated with increased breast cancer (BC)…”
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Phase I/II study of valproic acid (VPA) and short-course radiotherapy (SCRT) plus capecitabine (CAP) as preoperative treatment in low-moderate risk rectal cancer (V-shoRT-R3) by Budillon, A, Delrio, P, Pecori, B, Tatangelo, F, Di Gennaro, E, Romano, C, D'Angelo, V, Marone, P, Granata, C, Cavalacanti, E, De Stefano, A, Pace, U, Bianco, F, Petrillo, A, Lastoria, S, Botti, G, Muto, P, Perrone, F, Piccirillo, M C, Avallone, A

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TERT promoter and CTNNB1 gene mutations represent cancer signatures specific for hepatitis B and hepatitis C related hepatocellular carcinoma by Pezzuto, F, Izzo, F, Buonaguro, L, Annunziata, C, Tatangelo, F, Botti, G, Buonaguro, F.M, Tornesello, M.L

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