Search Results - "BOT, Pieter"

Interferon-β Signaling Is Enhanced in Patients With Insufficient Coronary Collateral Artery Development and Inhibits Arteriogenesis in Mice by Schirmer, Stephan H, Fledderus, Joost O, Bot, Pieter T.G, Moerland, Perry D, Hoefer, Imo E, Baan, Jan, Henriques, José P.S, van der Schaaf, René J, Vis, Marije M, Horrevoets, Anton J.G, Piek, Jan J, van Royen, Niels

“…Stimulation of collateral artery growth in patients has been hitherto unsuccessful, despite promising experimental approaches. Circulating monocytes are…”
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MRI of the “tiger” by Gho, Johannes, Bot, Pieter, Halbmeijer, Rick, Gürlek, Cihal, Hirsch, Alexander

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Increased Expression of the Transforming Growth Factor-β Signaling Pathway, Endoglin, and Early Growth Response-1 in Stable Plaques by Bot, Pieter T.G, Hoefer, Imo E, Sluijter, Joost P.G, van Vliet, Patrick, Smits, Anke M, Lebrin, Franck, Moll, Frans, de Vries, Jean-Paul, Doevendans, Pieter, Piek, Jan J, Pasterkamp, Gerard, Goumans, Marie-José

“…BACKGROUND AND PURPOSE—Unstable atherosclerotic plaques are characterized by increased macrophages and reduced smooth muscle cells (SMCs) and collagen content…”
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Hyaluronic acid: targeting immune modulatory components of the extracellular matrix in atherosclerosis by Bot, Pieter T, Hoefer, Imo E, Piek, Jan J, Pasterkamp, Gerard

“…Atherosclerosis is a chronic inflammatory disease of the vessel wall. Although it has become common knowledge that hyaluronic acid (HA), an important component…”
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A Late Complication in a Surgically Corrected ALCAPA Patient by Visser, Pascal C., Keijzers, Mitran, Delewi, Ronak, Lobatto, Mark E., Bot, Pieter T.

“…Late complications in surgically corrected ALCAPA patients are rare. We describe an interesting case of a patient with a thrombosed giant right coronary artery…”
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Forkhead box protein P1 as a downstream target of transforming growth factor-β induces collagen synthesis and correlates with a more stable plaque phenotype by Bot, Pieter T, Grundmann, Sebastian, Goumans, Marie-José, de Kleijn, Dominique, Moll, Frans, de Boer, Onno, van der Wal, Allard C, van Soest, Alex, de Vries, Jean-Paul, van Royen, Niels, Piek, Jan J, Pasterkamp, Gerard, Hoefer, Imo E

“…Abstract Objective Atherosclerosis is an inflammatory disease, modulated by plaque stabilizing and de-stabilizing cell populations such as infiltrating…”
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Hyaluronic acid metabolism is increased in unstable plaques by Bot, Pieter T., Pasterkamp, Gerard, Goumans, Marie-José, Strijder, Chaylendra, Moll, Frans L., De Vries, Jean-Paul, Pals, Steven T., De Kleijn, Dominique P., Piek, Jan J., Hoefer, Imo E.

“…Eur J Clin Invest 2010; 40 (9): 818–827 Background  Hyaluronic acid is expressed in atherosclerotic lesions, but its exact role in atherosclerotic disease…”
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Distinct CD44 splice variants differentially affect collateral artery growth by Bot, Pieter T, Grundmann, Sebastian, van Royen, Niels, Joosten, Sander P J, Schirmer, Stephan H, de Kleijn, Dominique P V, Pals, Steven T, Pasterkamp, Gerard, Piek, Jan J, Hoefer, Imo E

“…Lack of the adhesion molecule CD44 reduces collateral artery growth (arteriogenesis) in a murine hindlimb model. CD44 function is influenced by expression of…”
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Arteriogenesis requires toll-like receptor 2 and 4 expression in bone-marrow derived cells by de Groot, Daphne, Hoefer, Imo E, Grundmann, Sebastian, Schoneveld, Arjan, Haverslag, René T, van Keulen, J. Karlijn, Bot, Pieter T, Timmers, Leo, Piek, Jan J, Pasterkamp, Gerard, de Kleijn, Dominique P.V

“…Abstract Adaptive collateral growth (arteriogenesis) is an important protective mechanism against ischemic injury in patients with cardiovascular disease…”
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CASE-FB-08 - MRI of the “tiger” by Gho, Johannes, Bot, Pieter, Halbmeijer, Rick, Gürlek, Cihal, Hirsch, Alexander

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Uncertainties in the Bidirectional Biodiesel Supply Chain by Bot, Pieter, van Donk, Dirk Pieter, Pennink, Bartjan, Simatupang, Togar M.

“…For remote areas, small-scale local biodiesel production is particularly attractive if producers and consumers are the same. Such supply chains are labeled as…”
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Blocking Interferon β Stimulates Vascular Smooth Muscle Cell Proliferation and Arteriogenesis by Schirmer, Stephan H., Bot, Pieter T., Fledderus, Joost O., van der Laan, A.M., Volger, Oscar L., Laufs, Ulrich, Böhm, Michael, de Vries, Carlie J.M., Horrevoets, Anton J.G., Piek, Jan J., Hoefer, Imo E., van Royen, Niels

“…Increased interferon (IFN)-β signaling in patients with insufficient coronary collateralization and an inhibitory effect of IFNβ on collateral artery growth in…”
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A pilot study on stimulation of arteriogenesis using subcutaneous application of granulocyte-macrophage colony-stimulating factor as a new treatment for peripheral vascular disease by VAN ROYEN, Niels, SCHIRMER, Stephan H, BIEMOND, Bart J, TIJSSEN, J. G, BODE, Christoph, SCHAPER, Wolfgang, OSKAM, Jacques, LEGEMATE, Dink A, PIEK, Jan J, BUSCHMANN, Ivo, ATASEVER, Bektas, BEHRENS, Casper Y. H, UBBINK, Dirk, BUSCHMANN, Eva E, VOSKUIL, Michiel, BOT, Pieter, HOEFER, Imo, SCHLINGEMANN, Reinier O

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START Trial: a pilot study on STimulation of ARTeriogenesis using subcutaneous application of granulocyte-macrophage colony-stimulating factor as a new treatment for peripheral vascular disease by van Royen, Niels, Schirmer, Stephan H, Atasever, Bektas, Behrens, Casper Y H, Ubbink, Dirk, Buschmann, Eva E, Voskuil, Michiel, Bot, Pieter, Hoefer, Imo, Schlingemann, Reinier O, Biemond, Bart J, Tijssen, J G, Bode, Christoph, Schaper, Wolfgang, Oskam, Jacques, Legemate, Dink A, Piek, Jan J, Buschmann, Ivo

“…Granulocyte-macrophage colony-stimulating factor (GM-CSF) was recently shown to increase collateral flow index in patients with coronary artery disease…”
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Blocking Interferon b Stimulates Vascular Smooth Muscle Cell Proliferation and Arteriogenesis by Schirmer, Stephan H, Bot, Pieter T, Fledderus, Joost O, van der Laan, AM, Volger, Oscar L, Laufs, Ulrich, Boehm, Michael, de Vries, Carlie JM, Horrevoets, Anton JG, Piek, Jan J, Hoefer, Imo E, van Royen, Niels

“…Increased interferon (IFN)-b signaling in patients with insufficient coronary collateralization and an inhibitory effect of IFNb on collateral artery growth in…”
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Abstract 303: Arteriogenesis Requires Leukocytic Co-Signaling of TLR2 and TLR4 by Hoefer, Imo, Schoneveld, Arjan, Grundmann, Sebastian, van Keulen, Karlijn, Bot, Pieter, Timmers, Leo, Pasterkamp, Gerard, de Kleijn, Dominique

“…Abstract only Background: Collateral artery growth (arteriogenesis) is promoted by the accumulation of leukocytes in the perivascular tissue. Ligand binding to…”
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Blocking interferon {beta} stimulates vascular smooth muscle cell proliferation and arteriogenesis by Schirmer, Stephan H, Bot, Pieter T, Fledderus, Joost O, van der Laan, A M, Volger, Oscar L, Laufs, Ulrich, Böhm, Michael, de Vries, Carlie J M, Horrevoets, Anton J G, Piek, Jan J, Hoefer, Imo E, van Royen, Niels

“…Increased interferon (IFN)-β signaling in patients with insufficient coronary collateralization and an inhibitory effect of IFNβ on collateral artery growth in…”
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Congenital thrombocytopenia in adults by van Zweeden, Annette, Bot, Pieter, Smets, Yves, Terpstra, Wim

“…Thrombocytopenia in adult patients is usually acquired. Important causes are medication, pregnancy, infections and auto-immune disorders. Here we present 2…”
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