Search Results - "BOSSERHOFF, Anja K"

Loss of Gene Information: Discrepancies between RNA Sequencing, cDNA Microarray, and qRT-PCR by Rachinger, Nicole, Fischer, Stefan, Böhme, Ines, Linck-Paulus, Lisa, Kuphal, Silke, Kappelmann-Fenzl, Melanie, Bosserhoff, Anja K.

“…Molecular analyses of normal and diseased cells give insight into changes in gene expression and help in understanding the background of pathophysiological…”
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When Mechanical Stress Matters: Generation of Polyploid Giant Cancer Cells in Tumor‐Like Microcapsules by Antonelli, Yasmin, Krüger, René, Buehler, Adrian, Monavari, Mahshid, Fuentes‐Chandía, Miguel, Colombo, Federico, Palmisano, Ralf, Boßerhoff, Anja K., Kappelmann‐Fenzl, Melanie, Schödel, Johannes, Boccaccini, Aldo R., Selhuber‐Unkel, Christine, Letort, Gaelle, Leal‐Egaña, Aldo

“…Biofabrication techniques enable the performance of bioinspired three‐dimensional (3D) matrices resembling primary tumors. To validate their reliability,…”
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GLUT1 Expression Is Increased in Hepatocellular Carcinoma and Promotes Tumorigenesis by Amann, Thomas, Maegdefrau, Ulrike, Hartmann, Arndt, Agaimy, Abbas, Marienhagen, Jörg, Weiss, Thomas S, Stoeltzing, Oliver, Warnecke, Christina, Schölmerich, Jürgen, Oefner, Peter J, Kreutz, Marina, Bosserhoff, Anja K, Hellerbrand, Claus

“…Accelerated glycolysis is one of the biochemical characteristics of cancer cells. The glucose transporter isoform 1 ( GLUT1 ) gene encodes a key rate-limiting…”
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CYLD controls c-MYC expression through the JNK-dependent signaling pathway in hepatocellular carcinoma by Pannem, Rajeswara Rao, Dorn, Christoph, Ahlqvist, Kristofer, Bosserhoff, Anja K, Hellerbrand, Claus, Massoumi, Ramin

“…Posttranslational modification of different proteins via direct ubiquitin attachment is vital for mediating various cellular processes. Cylindromatosis (CYLD),…”
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Characterization of two different alginate-based bioinks and the influence of melanoma growth within by Schipka, Raphael, Heltmann-Meyer, Stefanie, Schneidereit, Dominik, Friedrich, Oliver, Röder, Jonas, Boccaccini, Aldo R., Schrüfer, Stefan, Schubert, Dirk W., Horch, Raymund E., Bosserhoff, Anja K., Arkudas, Andreas, Kengelbach-Weigand, Annika, Schmid, Rafael

“…Extrusion-based bioprinting is an established method in biofabrication. Suitable bioinks have fundamentally different compositions and characteristics, which…”
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Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma by Massoumi, Ramin, Kuphal, Silke, Hellerbrand, Claus, Haas, Bodo, Wild, Peter, Spruss, Thilo, Pfeifer, Alexander, Fässler, Reinhard, Bosserhoff, Anja K

“…High malignancy and early metastasis are hallmarks of melanoma. Here, we report that the transcription factor Snail1 inhibits expression of the tumor…”
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Impact of LIF (leukemia inhibitory factor) expression in malignant melanoma by Kuphal, Silke, Wallner, Susanne, Bosserhoff, Anja K.

“…Leukemia inhibitory factor (LIF) signaling regulates cellular processes to maintain the self-renewal and pluripotency of embryonic stem (ES) cells. Independent…”
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Novel bioimaging techniques of metals by laser ablation inductively coupled plasma mass spectrometry for diagnosis of fibrotic and cirrhotic liver disorders by M-M, Pornwilard, Weiskirchen, Ralf, Gassler, Nikolaus, Bosserhoff, Anja K, Becker, J Sabine

“…Hereditary disorders associated with metal overload or unwanted toxic accumulation of heavy metals can lead to morbidity and mortality. Patients with…”
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Amphiregulin Regulates Melanocytic Senescence by Pommer, Michaela, Kuphal, Silke, Bosserhoff, Anja K

“…Oncogene-induced senescence (OIS) is a decisive process to suppress tumor development, but the molecular details of OIS are still under investigation. Using an…”
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Tumor Cells Develop Defined Cellular Phenotypes After 3D-Bioprinting in Different Bioinks by Schmidt, Sonja K, Schmid, Rafael, Arkudas, Andreas, Kengelbach-Weigand, Annika, Bosserhoff, Anja K

“…Malignant melanoma is often used as a model tumor for the establishment of novel therapies. It is known that two-dimensional (2D) culture methods are not…”
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Fibrosing connective tissue disorders of the skin: Molecular similarities and distinctions by Canady, Johanna, Karrer, Sigrid, Fleck, Martin, Bosserhoff, Anja K

“…Abstract A variety of fibrosing connective tissue disorders of the skin have been described. They all share a characteristic activation of fibroblasts…”
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Pirin is a prognostic marker of human melanoma that dampens the proliferation of malignant cells by downregulating JARID1B/KDM5B expression by Penas, Cristina, Arroyo-Berdugo, Yoana, Apraiz, Aintzane, Rasero, Javier, Muñoa-Hoyos, Iraia, Andollo, Noelia, Cancho-Galán, Goikoane, Izu, Rosa, Gardeazabal, Jesús, Ezkurra, Pilar A., Subiran, Nerea, Alvarez-Dominguez, Carmen, Alonso, Santos, Bosserhoff, Anja K., Asumendi, Aintzane, Boyano, María D.

“…Originally considered to act as a transcriptional co-factor, Pirin has recently been reported to play a role in tumorigenesis and the malignant progression of…”
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Identification of novel targets of miR-622 in hepatocellular carcinoma reveals common regulation of cooperating genes and outlines the oncogenic role of zinc finger CCHC-type containing 11 by Gaza, Anne, Fritz, Valerie, Malek, Lara, Wormser, Laura, Treiber, Nora, Danner, Johannes, Kremer, Andreas E., Thasler, Wolfgang E., Siebler, Jürgen, Meister, Gunter, Neurath, Markus F., Hellerbrand, Claus, Bosserhoff, Anja K., Dietrich, Peter

“…The poor prognosis of advanced hepatocellular carcinoma (HCC) is driven by diverse features including dysregulated microRNAs inducing drug resistance and…”
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Multifrequency Investigation of Single- and Double-Stranded DNA with Scalable Metamaterial-Based THz Biosensors by Weisenstein, Christian, Richter, Merle, Wigger, Anna Katharina, Bosserhoff, Anja K., Haring Bolívar, Peter

“…Due to the occurrence of THz-excited vibrational modes in biomacromolecules, the THz frequency range has been identified as particularly suitable for…”
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HDAC2 Is Involved in the Regulation of BRN3A in Melanocytes and Melanoma by Heppt, Markus V, Wessely, Anja, Hornig, Eva, Kammerbauer, Claudia, Graf, Saskia A, Besch, Robert, French, Lars E, Matthies, Alexander, Kuphal, Silke, Kappelmann-Fenzl, Melanie, Bosserhoff, Anja K, Berking, Carola

“…The neural crest transcription factor BRN3A is essential for the proliferation and survival of melanoma cells. It is frequently expressed in melanoma but not…”
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Immunometabolic Determinants of Chemoradiotherapy Response and Survival in Head and Neck Squamous Cell Carcinoma by Krupar, Rosemarie, Hautmann, Matthias G., Pathak, Ravi R., Varier, Indu, McLaren, Cassandra, Gaag, Doris, Hellerbrand, Claus, Evert, Matthias, Laban, Simon, Idel, Christian, Sandulache, Vlad, Perner, Sven, Bosserhoff, Anja K., Sikora, Andrew G.

“…Tumor immune microenvironment and tumor metabolism are major determinants of chemoradiotherapy response. The interdependency and prognostic significance of…”
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The transcription factor activating enhancer‐binding protein epsilon (AP–2ε) regulates the core promoter of type II collagen (COL2A1) by Niebler, Stephan, Bosserhoff, Anja K.

“…The transcription factor activating enhancer‐binding protein epsilon (AP–2ε) was recently shown to be expressed during late chondrocyte differentiation,…”
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Dissimilar Appearances Are Deceptive-Common microRNAs and Therapeutic Strategies in Liver Cancer and Melanoma by Linck-Paulus, Lisa, Hellerbrand, Claus, Bosserhoff, Anja K, Dietrich, Peter

“…In this review, we summarize the current knowledge on miRNAs as therapeutic targets in two cancer types that were frequently described to be driven by…”
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Sox9 regulates melanocytic fate decision of adult hair follicle stem cells by Stüfchen, Isabel, Beyer, Felix, Staebler, Sebastian, Fischer, Stefan, Kappelmann, Melanie, Beckervordersandforth, Ruth, Bosserhoff, Anja K.

“…The bulge of hair follicles harbors Nestin+ (neural crest like) stem cells, which exhibit the potential to generate various cell types including melanocytes…”
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Encapsulation of Rat Bone Marrow Derived Mesenchymal Stem Cells in Alginate Dialdehyde/Gelatin Microbeads with and without Nanoscaled Bioactive Glass for In Vivo Bone Tissue Engineering by Rottensteiner-Brandl, Ulrike, Detsch, Rainer, Sarker, Bapi, Lingens, Lara, Köhn, Katrin, Kneser, Ulrich, Bosserhoff, Anja K, Horch, Raymund E, Boccaccini, Aldo R, Arkudas, Andreas

“…Alginate dialdehyde (ADA), gelatin, and nano-scaled bioactive glass (nBG) particles are being currently investigated for their potential use as…”
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