Search Results - "BOSMA, M. J"

The Scid Mouse Mutant: Definition, Characterization, and Potential Uses by Bosma, M J, Carroll, A M

“…Mice homozygous for the scid mutation (scid mice) are severely deficient in functional B and T lymphocytes. The mutation appears to impair the recombination of…”
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White matter, cognition and psychotic-like experiences in UK Biobank by Bosma, M J, Cox, S R, Ziermans, T, Buchanan, C R, Shen, X, Tucker-Drob, E M, Adams, M J, Whalley, H C, Lawrie, S M

“…Psychotic-like experiences (PLEs) are risk factors for the development of psychiatric conditions like schizophrenia, particularly if associated with distress…”
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Euthanasia, Physician-Assisted Suicide, and Other Medical Practices Involving the End of Life in the Netherlands, 1990–1995 by van der Maas, Paul J, van der Wal, Gerrit, Haverkate, Ilinka, de Graaff, Carmen L.M, Kester, John G.C, Onwuteaka-Philipsen, Bregje D, van der Heide, Agnes, Bosma, Jacqueline M, Willems, Dick L

“…In the Netherlands, euthanasia and physician-assisted suicide have been practiced with increasing openness, although technically they remain illegal. In…”
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V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes by Roth, D B, Menetski, J P, Nakajima, P B, Bosma, M J, Gellert, M

“…Lymphoid cells from scid mice initiate V(D)J recombination normally but have a severely reduced ability to join coding segments. Thymocytes from scid mice…”
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Evaluation of the Notification Procedure for Physician-Assisted Death in the Netherlands by van der Maas, Paul J, van der Wal, Gerrit, Haverkate, Ilinka, de Graaff, Carmen L.M, Kester, John G.C, Onwuteaka-Philipsen, Bregje D, van der Heide, Agnes, Bosma, Jacqueline M, Willems, Dick L, Kostense, Piet J

“…Medical decisions are normally made in the privacy of the doctor–patient relationship. 1 Decisions that involve physician-assisted death, however, require at…”
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Evidence of functional lymphocytes in some (leaky) scid mice by BOSMA, G. C, FRIED, M, CUSTER, R. P, CARROLL, A, GIBSON, D. M, BOSMA, M. J

“…Although the majority of severe combined immune deficiency (scid) mice lack functional lymphocytes, some (2-23%) appear to develop a limited number of B and T…”
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Severe combined immunodeficiency (SCID) in the mouse. Pathology, reconstitution, neoplasms by Custer, RP, Bosma, GC, Bosma, MJ

“…Histologic findings in mice with severe combined immunodeficiency (SCID) were remarkably uniform, consisting of lymphopenia, a rudimentary thymic medulla…”
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Natural killer (NK) cells are present in mice with severe combined immunodeficiency (scid) by Dorshkind, K, Pollack, SB, Bosma, MJ, Phillips, RA

“…Spleen cells from C.B- 17 scid mice with severe combined immunodeficiency disease exhibit natural killer cell (NK) activity against YAC lymphoma targets in a…”
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Reserved procedures in dutch hospitals: knowledge, experiences and views of physicians and nurses by de Bie, J, Cuperus-Bosma, J.M, Gevers, J.K.M, van der Wal, G

“…The Individual Health Care Professions Act came into force in The Netherlands in 1997, introducing a mixed system for the regulation of the practice of…”
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V(D)J recombination in mouse thymocytes: double-strand breaks near T cell receptor delta rearrangement signals by Roth, D B, Nakajima, P B, Menetski, J P, Bosma, M J, Gellert, M

“…In the murine T cell receptor delta locus, V(D)J recombination events frequently involve the D2 and J1 elements. Here we report the presence of double-strand…”
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The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination by Lieber, M R, Hesse, J E, Lewis, S, Bosma, G C, Rosenberg, N, Mizuuchi, K, Bosma, M J, Gellert, M

“…Pre-B and pre-T cell lines from mutant mice with severe combined immune deficiency (scid mice) were transfected with plasmids that contained recombination…”
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The disciplinary code for nurses and its contribution to the quality of nursing care in the Netherlands by Hout, F.A.G., Cuperus-Bosma, J.M., Hubben, J.H., van der Wal, G.

“…Aim: To obtain insight into the contribution of the disciplinary code for nurses to monitoring the quality of nursing care in the Netherlands. Methods:…”
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Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency by Schuler, W, Weiler, I J, Schuler, A, Phillips, R A, Rosenberg, N, Mak, T W, Kearney, J F, Perry, R P, Bosma, M J

“…A process unique to lymphocyte differentiation is the rearrangement of genes encoding antigen-specific receptors on B and T cells. A mouse mutant (C.B-17scid)…”
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Risky procedures by nurses in hospitals: problems and (contemplated) refusals of orders by physicians, and views of physicians and nurses. A questionnaire survey by de Bie, J., Cuperus-Bosma, J.M., van der Jagt, M.A.B., Gevers, J.K.M., van der Wal, G

“…Occurrence of problems with, refusals of orders and contemplated refusals of orders for risky procedures by nurses in Dutch hospitals and views on the safety…”
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A T cell-independent mechanism of macrophage activation by interferon- gamma by Bancroft, GJ, Schreiber, RD, Bosma, GC, Bosma, MJ, Unanue, ER

“…A primary interest in immunity to intracellular pathogenic microorganisms and tumors is to understand the mechanisms by which macrophages are activated for…”
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Risky procedures by nurses in hospitals: problems and (contemplated) refusals of orders by physicians, and views of physicians and nurses by de Bie, J., Cuperus-Bosma, J.M., van der Jagt, M.A.B., Gevers, J.K.M., van der Wal, G.

“…Occurrence of problems with, refusals of orders and contemplated refusals of orders for risky procedures by nurses in Dutch hospitals and views on the safety…”
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Functional status of cells from lymphoid and myeloid tissues in mice with severe combined immunodeficiency disease by Dorshkind, K, Keller, GM, Phillips, RA, Miller, RG, Bosma, GC, O'Toole, M, Bosma, MJ

“…Cells from mice with severe combined immunodeficiency disease (SCID) were tested in assays that measure myeloid and lymphoid function. Results showed that…”
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The mouse mutation severe combined immune deficiency (scid) is on chromosome 16 by BOSMA, G. C, DAVISSON, M. T, RUETSCH, N. R, SWEET, H. O, SHULTZ, L. D, BOSMA, M. J

“…To ascertain the chromosomal location of scid , different mouse linkage testing stocks that express one or more marker genes of known chromosomal location were…”
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Regulation of macrophage Ia expression in mice with severe combined immunodeficiency: induction of Ia expression by a T cell-independent mechanism by Bancroft, GJ, Bosma, MJ, Bosma, GC, Unanue, ER

“…We have studied the expression of Ia molecules by macrophages from mice with severe combined immunodeficiency (CB-17 scid) that lack demonstrable T cell and B…”
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Transplantable Progenitors of Natural Killer Cells are Distinct from Those of T and B Lymphocytes by Hackett, John, Bosma, Gayle C., Bosma, Melvin J., Bennett, Michael, Kumar, Vinay

“…We have utilized a mouse mutant (C.B-17 scid) that lacks functional T and B lymphocytes to examine the relationship among transplantable progenitors of natural…”
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