Search Results - "BOSKEY, A. L"

Aging and Bone by Boskey, A.L., Coleman, R.

“…Bones provide mechanical and protective function, while also serving as housing for marrow and a site for regulation of calcium ion homeostasis. The properties…”
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Spectroscopic markers of bone quality in alendronate-treated postmenopausal women by Boskey, A. L, Spevak, L, Weinstein, R. S

“…Summary Comparison of infrared spectroscopic images of sections from biopsies of placebo-treated post-menopausal women and women treated for 3 years with 10…”
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Comparison of mineral quality and quantity in iliac crest biopsies from high- and low-turnover osteoporosis : an FT-IR microspectroscopic investigation by BOSKEY, A. L, DICARLO, E, PASCHALIS, E, WEST, Paul, MENDELSOHN, Richard

“…Fourier-transform infrared microspectroscopy (FTIRM) allows analysis of mineral content, mineral crystal maturity and mineral composition at approximately…”
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Spectroscopic characterization of collagen cross-links in bone by Paschalis, E. P., Verdelis, K., Doty, S. B., Boskey, A. L., Mendelsohn, R., Yamauchi, M.

“…Collagen is the most abundant protein of the organic matrix in mineralizing tissues. One of its most critical properties is its cross-linking pattern. The…”
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Lathyrism-induced alterations in collagen cross-links influence the mechanical properties of bone material without affecting the mineral by Paschalis, E.P, Tatakis, D.N, Robins, S, Fratzl, P, Manjubala, I, Zoehrer, R, Gamsjaeger, S, Buchinger, B, Roschger, A, Phipps, R, Boskey, A.L, Dall'Ara, E, Varga, P, Zysset, P, Klaushofer, K, Roschger, P

“…Abstract In the present study a rat animal model of lathyrism was employed to decipher whether anatomically confined alterations in collagen cross-links are…”
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Importance of phosphorylation for osteopontin regulation of biomineralization by Gericke, A, Qin, C, Spevak, L, Fujimoto, Y, Butler, W T, Sørensen, E S, Boskey, A L

“…Previous in vitro and in vivo studies demonstrated that osteopontin (OPN) is an inhibitor of the formation and growth of hydroxyapatite (HA) and other…”
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Different Forms of DMP1 Play Distinct Roles in Mineralization by Gericke, A., Qin, C., Sun, Y., Redfern, R., Redfern, D., Fujimoto, Y., Taleb, H., Butler, W.T., Boskey, A.L.

“…Dentin matrix protein-1 (DMP1) is a major synthetic product of hypertrophic chondrocytes and osteocytes. Previous in vitro studies showed full-length DMP1…”
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MicroCT morphometry analysis of mouse cancellous bone: Intra- and inter-system reproducibility by Verdelis, K, Lukashova, L, Atti, E, Mayer-Kuckuk, P, Peterson, M.G.E, Tetradis, S, Boskey, A.L, van der Meulen, M.C.H

“…Abstract The agreement between measurements and the relative performance reproducibility among different microcomputed tomography (microCT) systems, especially…”
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The effect of lead on bone mineral properties from female adult C57/BL6 mice by Monir, A.U, Gundberg, C.M, Yagerman, S.E, van der Meulen, M.C.H, Budell, W.C, Boskey, A.L, Dowd, T.L

“…Abstract Lead toxicity is a significant problem in the U.S. with elevated blood lead levels being highest among very young children and older adults > 50 years…”
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Comparable outcomes in fracture reduction and bone properties with RANKL inhibition and alendronate treatment in a mouse model of osteogenesis imperfecta by Bargman, R., Posham, R., Boskey, A. L., DiCarlo, E., Raggio, C., Pleshko, N.

“…Summary We report a direct comparison of receptor activator of nuclear factor kappa B ligand (RANKL) inhibition (RANK-Fc) with bisphosphonate treatment…”
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Thermal and chemical modification of titanium–aluminum–vanadium implant materials: effects on surface properties, glycoprotein adsorption, and MG63 cell attachment by MacDonald, D.E, Rapuano, B.E, Deo, N, Stranick, M, Somasundaran, P, Boskey, A.L

“…The microstructure, chemical composition and wettability of thermally and chemically modified Ti–6Al–4 V alloy disks were characterized and correlated with the…”
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Maturational changes in dentin mineral properties by Verdelis, K, Lukashova, L, Wright, J.T, Mendelsohn, R, Peterson, M.G.E, Doty, S, Boskey, A.L

“…Abstract In this study the changes in properties of the maturing mantle and circumpulpal dentin were quantitatively analyzed. Sections from six fetal bovine…”
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Diffusion systems for evaluation of biomineralization by Silverman, L, Boskey, A L

“…A variety of in vitro study methods have been used to elucidate the roles of matrix molecules in biomineralization processes. Among these, gel…”
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Distribution of Collagen Cross‐Links in Normal Human Trabecular Bone by Paschalis, EP, Recker, R, Dicarlo, E, Doty, SB, Atti, E, Boskey, AL

“…Infrared imaging analysis of normal human iliac crest biopsy specimens shows a characteristic spatial variation in the nonreducible:reducible collagen…”
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Collagen and Bone Strength by Boskey, A. L., Wright, T. M., Blank, R. D.

“…The purpose of this commentary is to review additional documentation for that view while indicating the limitations of the present study. First, we briefly…”
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Osteopontin deficiency increases mineral content and mineral crystallinity in mouse bone by Boskey, A L, Spevak, L, Paschalis, E, Doty, S B, McKee, M D

“…Fourier transform infrared microspectroscopy (FTIRM) and infrared imaging (FTIRI) were used to characterize the mineral in bones of two different lines of…”
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A physical, chemical, and mechanical study of lumbar vertebrae from normal, ovariectomized, and nandrolone decanoate-treated cynomolgus monkeys ( macaca fascicularis) by Gadeleta, S.J, Boskey, A.L, Paschalis, E, Carlson, C, Menschik, F, Baldini, T, Peterson, M, Rimnac, C.M

“…Ovariectomized cynomolgus monkeys have previously been investigated as a nonhuman primate model of postmenopausal osteoporosis (Jerome et al., Bone Miner…”
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Fourier transform infrared microspectroscopic analysis of bones of osteocalcin-deficient mice provides insight into the function of osteocalcin by Boskey, A.L, Gadaleta, S, Gundberg, C, Doty, S.B, Ducy, P, Karsenty, G

“…Osteocalcin, the γ-carboxyglutamic acid-containing protein, which in most species is the predominant noncollagenous protein of bone and dentin, has been…”
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Complementary information on bone ultrastructure from scanning small angle X-ray scattering and Fourier-transform infrared microspectroscopy by Camacho, N.P, Rinnerthaler, S, Paschalis, E.P, Mendelsohn, R, Boskey, A.L, Fratzl, P

“…Scanning small angle X-ray scattering (scanning SAXS) and Fourier-transform infrared microspectroscopy (FT-IRM) have previously been utilized independently to…”
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Effect of Hormone Replacement Therapy on Bone Quality in Early Postmenopausal Women by Paschalis, Ep, Boskey, Al, Kassem, M, Eriksen, Ef

“…HRT is an effective prophylaxis against postmenopausal bone loss. Infrared imaging of paired iliac crest biopsies obtained at baseline and after 2 years of HRT…”
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