Search Results - "BORTHWICK, Iain A."

Control of 5-aminolevulinate synthase in animals by May, B K, Borthwick, I A, Srivastava, G, Pirola, B A, Elliott, W H

“…The proposed mechanism by which hepatic ALV-synthase mitochondrial levels are regulated is outlined in Fig. 2. ALV-synthase catalyzes the first and…”
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Identification of regulatory sequences in the gene for 5-aminolevulinate synthase from rat by BRAIDOTTI, G, BORTHWICK, I. A, MAY, B. K

“…The housekeeping enzyme 5-aminolevulinate synthase (ALAS) regulates the supply of heme for respiratory cytochromes. Here we report on the isolation of a…”
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Nudeotide sequence of the chicken 5-aminolevulinate synthase gene by Maguire, Deborah J., Day, Adrienne R., Borthwick, Iain A., Srivastava, Gopesh, Wigley, Peter L., May, Brian K., Elliott, William H.

“…5-Aminolevul inate synthase, the first and rate-controlling enzyme of heme biosynthesis, is regulated in the liver by the end-product heme. To study this…”
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Hemin inhibits transfer of pre-delta-aminolevulinate synthase into chick embryo liver mitochondria by Srivastava, G, Borthwick, I A, Brooker, J D, Wallace, J C, May, B K, Elliott, W H

“…Pulse labelling studies in chick embryo livers show that hemin prevents the transfer of drug induced pre-delta-aminolevulinate synthase from the cytosol into…”
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Purification of rat liver mitochondrial delta-aminolaevulinate synthase by Srivastava, G, Borthwick, I A, Brooker, J D, May, B K, Elliott, W H

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Purification of hepatic mitochondrial 5-aminolevulinate synthase by Borthwick, I A, Srivastava, G, Pirola, B A, May, B K, Elliott, W H

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Complete nucleotide sequence of hepatic 5‐aminolaevulinate synthase precursor by BORTHWICK, Iain A., SRIVASTAVA, Gopesh, DAY, Adrienne R., PIROLA, Byron A., SNOSWELL, Mark A., MAY, Brian K., ELLIOTT, William H.

“…Chick embryo liver mitochondrial matrix protein, 5‐aminolaevulinate synthase, is synthesised initially as a larger cytosolic precursor. In this report we…”
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Evidence for a cytosolic precursor of chick embryo liver mitochondrial delta-aminolevulinate synthase by Srivastava, G, Borthwick, I A, Brooker, J D, May, B K, Elliott, W H

“…Following the recent demonstration [Borthwick, I.A., Srivastava, G., Brooker, J.D., May, B.K. and Elliott, W.H. (1982) Eur. J. Biochem. in press] that chick…”
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Evidence that 2‐allyl‐2‐isopropylacetamide, phenobarbital and 3,5‐diethoxycarbonyl‐1,4‐dihydrocollidine induce the same cytochrome P 450 mRNA in chick embryo liver by BROOKER, John D., SRIVASTAVA, Gopesh, BORTHWICK, Iain A., MAY, Brian K., ELLIOTT, William H.

“…The induction of cytochrome P 450 in chick embryo liver has been studied using three different porphyrinogenic drugs, 2‐allyl‐2‐isopropylacetamide,…”
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Evidence that 2-allyl-2-isopropylacetamide, phenobarbital and 3,5-diethoxycarbonyl-1,4-dihydrocollidine induce the same cytochrome P450 mRNA in chick embryo liver by Brooker, J.D, Srivastava, G, Borthwick, I.A, May, B.K, Elliott, W.H

“…The induction of cytochrome P450 in chick embryo liver has been studied using three different porphyrinogenic drugs, 2‐allyl‐2‐isopropylacetamide,…”
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Characterisation of cis-acting DNA sequences required for the expression of the chicken 5-aminolevulinate synthase gene in Xenopus oocytes by Loveridge, J A, Borthwick, I A, May, B K, Elliott, W H

“…In this paper, we have constructed deletion and deletion-insertion mutations of the chicken 5-aminolevulinate synthase 5' flanking region and examined the…”
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Purification of 5-aminolaevulinate synthase from liver mitochondria of chick embryo by Borthwick, A, Srivastava, G, Brooker, J.D, May, B.K, Elliott, W.H

“…5‐Aminolaevulinate synthase from chick‐embryo liver mitochondria has, for the first time, been purified to homogeneity in its native non‐degraded form by…”
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Electron microscopic studies on liver 5‐aminolaevulinate synthase by PIROLA, Byron A., MAYER, Frank, BORTHWICK, Iain A., SRIVASTAVA, Gopesh, MAY, Brian K., ELLIOTT, William H.

“…The structure of chick embryo liver 5‐aminolaevulinate synthase has been examined by electron microscopic studies using negative staining. From the different…”
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Molecular cloning of hepatic 5‐aminolevulinate synthase by BORTHWICK, Iain A., SRIVASTAVA, Gopesh, HOBBS, Andrew A., PIROLA, Byron A., BROOKER, John D., MAY, Brian K., ELLIOTT, William H.

“…Hepatic 5‐aminolevulinate synthase was induced in chick embryos by administration of the porphyrinogenic drugs 2‐allyl‐2‐isopropylacetamide and…”
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